id | TP53 | VariantID | Class | ConseqType | AA | AAcoord | sift_sort | SIFT | polyphen_sort | polyphen_class | PolyPhen | cadd_sort | cadd_class | CADD |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | id | Variant ID | Class | Conseq. Type | AA | AA coord | sift_sort | SIFT | polyphen_sort | polyphen_class | PolyPhen | cadd_sort | cadd_class | CADD |
2 | TP53 | rs1567535890 | SNP | missense variant | H/Y | 342 | 292 | benign | 0.291 | 2001 | likely benign | 2 | ||
3 | TP53 | rs764432741 | SNP | missense variant | S/P | 341 | 251 | benign | 0.25 | 1 | likely benign | 0 | ||
4 | TP53 | rs1378564917 | SNP | missense variant | G/E | 340 | 970 | probably damaging | 0.969 | 2001 | likely benign | 2 | ||
5 | TP53 | rs753947213 | SNP | missense variant | G/R | 340 | 980 | probably damaging | 0.979 | 4001 | likely benign | 4 | ||
6 | TP53 | rs554512119 | SNP | missense variant | G/R | 339 | 1 | benign | 0 | 1 | likely benign | 0 | ||
7 | TP53 | rs554512119 | SNP | missense variant | G/S | 339 | 1 | benign | 0 | 1 | likely benign | 0 | ||
8 | TP53 | rs144366923 | SNP | missense variant | R/T | 337 | 1 | 0 | 96 | benign | 0.095 | 1001 | likely benign | 1 |
9 | TP53 | rs1483708811 | SNP | missense variant | P/L | 335 | 131 | 0.13 | 1 | benign | 0 | 5001 | likely benign | 5 |
10 | TP53 | rs1486846348 | SNP | missense variant | T/I | 333 | 71 | 0.07 | 106 | benign | 0.105 | 2001 | likely benign | 2 |
11 | TP53 | rs868721462 | SNP | missense variant | T/A | 333 | 161 | 0.16 | 13 | benign | 0.012 | 6001 | likely benign | 6 |
12 | TP53 | rs1207613599 | SNP | missense variant | K/R | 332 | 31 | 0.03 | 1 | benign | 0 | 3001 | likely benign | 3 |
13 | TP53 | rs11575996 | SNP | missense variant | Q/H | 331 | 11 | 0.01 | 252 | benign | 0.251 | 33001 | likely deleterious | 33 |
14 | TP53 | rs1064795056 | SNP | missense variant | Q/R | 331 | 41 | 0.04 | 787 | possibly damaging | 0.786 | 24001 | likely benign | 24 |
15 | TP53 | rs969930693 | SNP | missense variant | T/I | 329 | 31 | 0.03 | 323 | benign | 0.322 | 21001 | likely benign | 21 |
16 | TP53 | rs1000256867 | SNP | missense variant | E/D | 326 | 111 | 0.11 | 423 | benign | 0.422 | 21001 | likely benign | 21 |
17 | TP53 | rs1000256867 | SNP | missense variant | E/D | 326 | 111 | 0.11 | 423 | benign | 0.422 | 21001 | likely benign | 21 |
18 | TP53 | rs121912659 | SNP | missense variant | G/V | 325 | 171 | 0.17 | 256 | benign | 0.255 | 18001 | likely benign | 18 |
19 | TP53 | rs121912659 | SNP | missense variant | G/E | 325 | 1001 | 1 | 4 | benign | 0.003 | 8001 | likely benign | 8 |
20 | TP53 | rs863224500 | SNP | missense variant | G/R | 325 | 331 | 0.33 | 19 | benign | 0.018 | 23001 | likely benign | 23 |
21 | TP53 | rs1177881399 | SNP | missense variant | D/G | 324 | 1 | 0 | 891 | possibly damaging | 0.89 | 32001 | likely deleterious | 32 |
22 | TP53 | rs1064794810 | SNP | missense variant | D/Y | 324 | 1 | 0 | 986 | probably damaging | 0.985 | 26001 | likely benign | 26 |
23 | TP53 | rs1064794810 | SNP | missense variant | D/H | 324 | 1 | 0 | 971 | probably damaging | 0.97 | 25001 | likely benign | 25 |
24 | TP53 | rs1064794810 | SNP | missense variant | D/N | 324 | 51 | 0.05 | 300 | benign | 0.299 | 23001 | likely benign | 23 |
25 | TP53 | rs1432281680 | SNP | missense variant | L/V | 323 | 511 | 0.51 | 50 | benign | 0.049 | 12001 | likely benign | 12 |
26 | TP53 | rs863224687 | SNP | missense variant | P/S | 322 | 351 | 0.35 | 38 | benign | 0.037 | 17001 | likely benign | 17 |
27 | TP53 | rs863224687 | SNP | missense variant | P/T | 322 | 81 | 0.08 | 30 | benign | 0.029 | 17001 | likely benign | 17 |
28 | TP53 | rs1555524975 | SNP | missense variant | P/L | 318 | 11 | 0.01 | 463 | possibly damaging | 0.462 | 19001 | likely benign | 19 |
29 | TP53 | rs1060501199 | SNP | missense variant | Q/H | 317 | 101 | 0.1 | 606 | possibly damaging | 0.605 | 14001 | likely benign | 14 |
30 | TP53 | rs1159579789 | SNP | missense variant | Q/R | 317 | 441 | 0.44 | 143 | benign | 0.142 | 9001 | likely benign | 9 |
31 | TP53 | rs764735889 | SNP | missense variant | Q/K | 317 | 1001 | 1 | 8 | benign | 0.007 | 9001 | likely benign | 9 |
32 | TP53 | rs1555524979 | SNP | missense variant | P/L | 316 | 41 | 0.04 | 251 | benign | 0.25 | 22001 | likely benign | 22 |
33 | TP53 | rs772773208 | SNP | missense variant | P/T | 316 | 411 | 0.41 | 21 | benign | 0.02 | 19001 | likely benign | 19 |
34 | TP53 | rs762620193 | SNP | missense variant | S/T | 315 | 171 | 0.17 | 21 | benign | 0.02 | 16001 | likely benign | 16 |
35 | TP53 | rs751440465 | SNP | missense variant | S/F | 314 | 111 | 0.11 | 112 | benign | 0.111 | 22001 | likely benign | 22 |
36 | TP53 | rs1367492395 | SNP | missense variant | S/R | 313 | 41 | 0.04 | 569 | possibly damaging | 0.568 | 18001 | likely benign | 18 |
37 | TP53 | rs145151284 | SNP | missense variant | T/S | 312 | 261 | 0.26 | 20 | benign | 0.019 | 13001 | likely benign | 13 |
38 | TP53 | rs56184981 | SNP | missense variant | N/S | 311 | 1001 | 1 | 2 | benign | 0.001 | 1 | likely benign | 0 |
39 | TP53 | rs56184981 | SNP | missense variant | N/T | 311 | 811 | 0.81 | 1 | benign | 0 | 1 | likely benign | 0 |
40 | TP53 | rs1555525007 | SNP | missense variant | N/H | 311 | 161 | 0.16 | 8 | benign | 0.007 | 4001 | likely benign | 4 |
41 | TP53 | rs876660829 | SNP | missense variant | N/K | 310 | 601 | 0.6 | 1 | benign | 0 | 1 | likely benign | 0 |
42 | TP53 | rs876660829 | SNP | missense variant | N/K | 310 | 601 | 0.6 | 1 | benign | 0 | 1 | likely benign | 0 |
43 | TP53 | rs1555525012 | SNP | missense variant | P/S | 309 | 361 | 0.36 | 51 | benign | 0.05 | 17001 | likely benign | 17 |
44 | TP53 | rs1457582183 | SNP | missense variant | A/V | 307 | 81 | 0.08 | 107 | benign | 0.106 | 10001 | likely benign | 10 |
45 | TP53 | rs1457582183 | SNP | missense variant | A/G | 307 | 241 | 0.24 | 163 | benign | 0.162 | 10001 | likely benign | 10 |
46 | TP53 | rs1048095040 | SNP | missense variant | R/Q | 306 | 41 | 0.04 | 612 | possibly damaging | 0.611 | 22001 | likely benign | 22 |
47 | TP53 | rs587782654 | SNP | missense variant | T/A | 304 | 351 | 0.35 | 12 | benign | 0.011 | 14001 | likely benign | 14 |
48 | TP53 | rs876658714 | SNP | missense variant | S/N | 303 | 121 | 0.12 | 30 | benign | 0.029 | 15001 | likely benign | 15 |
49 | TP53 | rs587782391 | SNP | missense variant | S/G | 303 | 271 | 0.27 | 18 | benign | 0.017 | 20001 | likely benign | 20 |
50 | TP53 | rs1060501202 | SNP | missense variant | G/E | 302 | 151 | 0.15 | 153 | benign | 0.152 | 15001 | likely benign | 15 |
51 | TP53 | rs863224686 | SNP | missense variant | G/R | 302 | 131 | 0.13 | 42 | benign | 0.041 | 10001 | likely benign | 10 |
52 | TP53 | rs1555525067 | SNP | missense variant | P/L | 301 | 41 | 0.04 | 13 | benign | 0.012 | 12001 | likely benign | 12 |
53 | TP53 | rs909643864 | SNP | missense variant | P/L | 300 | 11 | 0.01 | 382 | benign | 0.381 | 20001 | likely benign | 20 |
54 | TP53 | rs201744589 | SNP | missense variant | E/Q | 298 | 141 | 0.14 | 39 | benign | 0.038 | 1 | likely benign | 0 |
55 | TP53 | rs201744589 | SNP | missense variant | E/K | 298 | 231 | 0.23 | 8 | benign | 0.007 | 1001 | likely benign | 1 |
56 | TP53 | rs876659477 | SNP | missense variant | H/R | 297 | 211 | 0.21 | 1 | benign | 0 | 4001 | likely benign | 4 |
57 | TP53 | rs483352696 | SNP | missense variant | H/R | 296 | 531 | 0.53 | 1 | benign | 0 | 1001 | likely benign | 1 |
58 | TP53 | rs672601296 | SNP | missense variant | H/Y | 296 | 41 | 0.04 | 16 | benign | 0.015 | 3001 | likely benign | 3 |
59 | TP53 | rs751713111 | SNP | missense variant | P/L | 295 | 201 | 0.2 | 8 | benign | 0.007 | 11001 | likely benign | 11 |
60 | TP53 | rs751713111 | SNP | missense variant | P/R | 295 | 151 | 0.15 | 21 | benign | 0.02 | 10001 | likely benign | 10 |
61 | TP53 | rs1131691006 | SNP | missense variant | P/S | 295 | 411 | 0.41 | 2 | benign | 0.001 | 1 | likely benign | 0 |
62 | TP53 | rs1305324490 | SNP | missense variant | E/D | 294 | 181 | 0.18 | 57 | benign | 0.056 | 3001 | likely benign | 3 |
63 | TP53 | rs587780076 | SNP | missense variant | G/W | 293 | 161 | 0.16 | 30 | benign | 0.029 | 18001 | likely benign | 18 |
64 | TP53 | rs587780076 | SNP | missense variant | G/R | 293 | 461 | 0.46 | 486 | possibly damaging | 0.485 | 15001 | likely benign | 15 |
65 | TP53 | rs121912663 | SNP | missense variant | K/I | 292 | 1 | 0 | 744 | possibly damaging | 0.743 | 23001 | likely benign | 23 |
66 | TP53 | rs121912663 | SNP | missense variant | K/R | 292 | 161 | 0.16 | 32 | benign | 0.031 | 21001 | likely benign | 21 |
67 | TP53 | rs372613518 | SNP | missense variant | K/N | 291 | 71 | 0.07 | 146 | benign | 0.145 | 18001 | likely benign | 18 |
68 | TP53 | rs781490101 | SNP | missense variant | K/R | 291 | 11 | 0.01 | 158 | benign | 0.157 | 25001 | likely benign | 25 |
69 | TP53 | rs1555525126 | SNP | missense variant | K/E | 291 | 191 | 0.19 | 696 | possibly damaging | 0.695 | 24001 | likely benign | 24 |
70 | TP53 | rs1060501205 | substitution | missense variant | RK/RQ | 290 | - | - | ||||||
71 | TP53 | rs55819519 | SNP | missense variant | R/L | 290 | 61 | 0.06 | 16 | benign | 0.015 | 3001 | likely benign | 3 |
72 | TP53 | rs55819519 | SNP | missense variant | R/P | 290 | 11 | 0.01 | 864 | possibly damaging | 0.863 | 13001 | likely benign | 13 |
73 | TP53 | rs55819519 | SNP | missense variant | R/H | 290 | 351 | 0.35 | 6 | benign | 0.005 | 1001 | likely benign | 1 |
74 | TP53 | rs770374782 | SNP | missense variant | R/C | 290 | 1 | 0 | 878 | possibly damaging | 0.877 | 26001 | likely benign | 26 |
75 | TP53 | rs770374782 | SNP | missense variant | R/G | 290 | 51 | 0.05 | 647 | possibly damaging | 0.646 | 22001 | likely benign | 22 |
76 | TP53 | rs1555525154 | SNP | missense variant | L/V | 289 | 41 | 0.04 | 1 | benign | 0 | 12001 | likely benign | 12 |
77 | TP53 | rs748891343 | SNP | missense variant | E/D | 287 | 651 | 0.65 | 28 | benign | 0.027 | 4001 | likely benign | 4 |
78 | TP53 | rs587782006 | SNP | missense variant | E/K | 287 | 21 | 0.02 | 224 | benign | 0.223 | 23001 | likely benign | 23 |
79 | TP53 | rs1057519985 | SNP | missense variant | E/V | 286 | 1 | 0 | 710 | possibly damaging | 0.709 | 32001 | likely deleterious | 32 |
80 | TP53 | rs1057519985 | SNP | missense variant | E/G | 286 | 1 | 0 | 991 | probably damaging | 0.99 | 32001 | likely deleterious | 32 |
81 | TP53 | rs1057519985 | SNP | missense variant | E/A | 286 | 1 | 0 | 985 | probably damaging | 0.984 | 31001 | likely deleterious | 31 |
82 | TP53 | rs786201059 | SNP | missense variant | E/Q | 286 | 1 | 0 | 984 | probably damaging | 0.983 | 27001 | likely benign | 27 |
83 | TP53 | rs786201059 | SNP | missense variant | E/K | 286 | 1 | 0 | 978 | probably damaging | 0.977 | 29001 | likely benign | 29 |
84 | TP53 | rs121912667 | SNP | missense variant | E/V | 285 | 1 | 0 | 984 | probably damaging | 0.983 | 29001 | likely benign | 29 |
85 | TP53 | rs112431538 | SNP | missense variant | E/K | 285 | 1 | 0 | 958 | probably damaging | 0.957 | 28001 | likely benign | 28 |
86 | TP53 | rs863224685 | SNP | missense variant | T/I | 284 | 21 | 0.02 | 364 | benign | 0.363 | 26001 | likely benign | 26 |
87 | TP53 | rs1204379654 | SNP | missense variant | T/S | 284 | 161 | 0.16 | 77 | benign | 0.076 | 23001 | likely benign | 23 |
88 | TP53 | rs1204379654 | SNP | missense variant | T/P | 284 | 1 | 0 | 930 | probably damaging | 0.929 | 26001 | likely benign | 26 |
89 | TP53 | rs371409680 | SNP | missense variant | R/P | 283 | 1 | 0 | 952 | probably damaging | 0.951 | 27001 | likely benign | 27 |
90 | TP53 | rs371409680 | SNP | missense variant | R/H | 283 | 41 | 0.04 | 103 | benign | 0.102 | 26001 | likely benign | 26 |
91 | TP53 | rs149633775 | SNP | missense variant | R/C | 283 | 51 | 0.05 | 128 | benign | 0.127 | 23001 | likely benign | 23 |
92 | TP53 | rs149633775 | SNP | missense variant | R/G | 283 | 21 | 0.02 | 136 | benign | 0.135 | 24001 | likely benign | 24 |
93 | TP53 | rs149633775 | SNP | missense variant | R/S | 283 | 41 | 0.04 | 451 | possibly damaging | 0.45 | 22001 | likely benign | 22 |
94 | TP53 | rs730882008 | SNP | missense variant | R/L | 282 | 1 | 0 | 710 | possibly damaging | 0.709 | 28001 | likely benign | 28 |
95 | TP53 | rs730882008 | SNP | missense variant | R/P | 282 | 1 | 0 | 997 | probably damaging | 0.996 | 29001 | likely benign | 29 |
96 | TP53 | rs730882008 | SNP | missense variant | R/Q | 282 | 1 | 0 | 963 | probably damaging | 0.962 | 28001 | likely benign | 28 |
97 | TP53 | rs28934574 | SNP | missense variant | R/W | 282 | 1 | 0 | 1000 | probably damaging | 0.999 | 31001 | likely deleterious | 31 |
98 | TP53 | rs28934574 | SNP | missense variant | R/G | 282 | 21 | 0.02 | 631 | possibly damaging | 0.63 | 27001 | likely benign | 27 |
99 | TP53 | rs1057519984 | SNP | missense variant | D/E | 281 | 1 | 0 | 516 | possibly damaging | 0.515 | 24001 | likely benign | 24 |
100 | TP53 | rs1057519984 | SNP | missense variant | D/E | 281 | 1 | 0 | 516 | possibly damaging | 0.515 | 24001 | likely benign | 24 |
101 | TP53 | rs587781525 | SNP | missense variant | D/V | 281 | 1 | 0 | 978 | probably damaging | 0.977 | 29001 | likely benign | 29 |
102 | TP53 | rs587781525 | SNP | missense variant | D/G | 281 | 11 | 0.01 | 995 | probably damaging | 0.994 | 31001 | likely deleterious | 31 |
103 | TP53 | rs587781525 | SNP | missense variant | D/A | 281 | 1 | 0 | 983 | probably damaging | 0.982 | 31001 | likely deleterious | 31 |
104 | TP53 | rs764146326 | SNP | missense variant | D/Y | 281 | 1 | 0 | 994 | probably damaging | 0.993 | 28001 | likely benign | 28 |
105 | TP53 | rs764146326 | SNP | missense variant | D/H | 281 | 51 | 0.05 | 603 | possibly damaging | 0.602 | 24001 | likely benign | 24 |
106 | TP53 | rs764146326 | SNP | missense variant | D/N | 281 | 11 | 0.01 | 976 | probably damaging | 0.975 | 28001 | likely benign | 28 |
107 | TP53 | rs1567547687 | SNP | missense variant | R/S | 280 | 21 | 0.02 | 762 | possibly damaging | 0.761 | 24001 | likely benign | 24 |
108 | TP53 | rs121912660 | SNP | missense variant | R/I | 280 | 1 | 0 | 980 | probably damaging | 0.979 | 30001 | likely deleterious | 30 |
109 | TP53 | rs121912660 | SNP | missense variant | R/T | 280 | 1 | 0 | 967 | probably damaging | 0.966 | 28001 | likely benign | 28 |
110 | TP53 | rs121912660 | SNP | missense variant | R/K | 280 | 31 | 0.03 | 589 | possibly damaging | 0.588 | 27001 | likely benign | 27 |
111 | TP53 | rs753660142 | SNP | missense variant | R/G | 280 | 1 | 0 | 967 | probably damaging | 0.966 | 28001 | likely benign | 28 |
112 | TP53 | rs1064793881 | SNP | missense variant | G/E | 279 | 1 | 0 | 1001 | probably damaging | 1 | 25001 | likely benign | 25 |
113 | TP53 | rs1555525248 | SNP | missense variant | G/R | 279 | 21 | 0.02 | 1000 | probably damaging | 0.999 | 33001 | likely deleterious | 33 |
114 | TP53 | rs876659802 | SNP | missense variant | P/L | 278 | 21 | 0.02 | 997 | probably damaging | 0.996 | 32001 | likely deleterious | 32 |
115 | TP53 | rs876659802 | SNP | missense variant | P/R | 278 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
116 | TP53 | rs876659802 | SNP | missense variant | P/H | 278 | 1 | 0 | 1000 | probably damaging | 0.999 | 29001 | likely benign | 29 |
117 | TP53 | rs17849781 | SNP | missense variant | P/S | 278 | 21 | 0.02 | 965 | probably damaging | 0.964 | 28001 | likely benign | 28 |
118 | TP53 | rs17849781 | SNP | missense variant | P/A | 278 | 1 | 0 | 975 | probably damaging | 0.974 | 27001 | likely benign | 27 |
119 | TP53 | rs17849781 | SNP | missense variant | P/T | 278 | 1 | 0 | 995 | probably damaging | 0.994 | 28001 | likely benign | 28 |
120 | TP53 | rs763098116 | SNP | missense variant | C/F | 277 | 1 | 0 | 978 | probably damaging | 0.977 | 27001 | likely benign | 27 |
121 | TP53 | rs763098116 | SNP | missense variant | C/Y | 277 | 1 | 0 | 978 | probably damaging | 0.977 | 26001 | likely benign | 26 |
122 | TP53 | rs1064795369 | SNP | missense variant | C/G | 277 | 21 | 0.02 | 983 | probably damaging | 0.982 | 28001 | likely benign | 28 |
123 | TP53 | rs1064795369 | SNP | missense variant | C/R | 277 | 1 | 0 | 992 | probably damaging | 0.991 | 31001 | likely deleterious | 31 |
124 | TP53 | rs786202082 | SNP | missense variant | A/G | 276 | 1 | 0 | 912 | probably damaging | 0.911 | 29001 | likely benign | 29 |
125 | TP53 | rs786202082 | SNP | missense variant | A/D | 276 | 1 | 0 | 970 | probably damaging | 0.969 | 29001 | likely benign | 29 |
126 | TP53 | rs1131691029 | SNP | missense variant | A/P | 276 | 21 | 0.02 | 988 | probably damaging | 0.987 | 27001 | likely benign | 27 |
127 | TP53 | rs1555525279 | SNP | missense variant | C/W | 275 | 1 | 0 | 1000 | probably damaging | 0.999 | 29001 | likely benign | 29 |
128 | TP53 | rs863224451 | SNP | missense variant | C/F | 275 | 1 | 0 | 992 | probably damaging | 0.991 | 27001 | likely benign | 27 |
129 | TP53 | rs863224451 | SNP | missense variant | C/S | 275 | 1 | 0 | 990 | probably damaging | 0.989 | 29001 | likely benign | 29 |
130 | TP53 | rs863224451 | SNP | missense variant | C/Y | 275 | 1 | 0 | 998 | probably damaging | 0.997 | 27001 | likely benign | 27 |
131 | TP53 | rs1057519983 | SNP | missense variant | C/R | 275 | 1 | 0 | 998 | probably damaging | 0.997 | 31001 | likely deleterious | 31 |
132 | TP53 | rs1057520006 | SNP | missense variant | V/G | 274 | 1 | 0 | 999 | probably damaging | 0.998 | 27001 | likely benign | 27 |
133 | TP53 | rs1057520006 | SNP | missense variant | V/A | 274 | 1 | 0 | 885 | possibly damaging | 0.884 | 27001 | likely benign | 27 |
134 | TP53 | rs1057520006 | SNP | missense variant | V/D | 274 | 1 | 0 | 997 | probably damaging | 0.996 | 28001 | likely benign | 28 |
135 | TP53 | rs1057520005 | SNP | missense variant | V/F | 274 | 41 | 0.04 | 315 | benign | 0.314 | 21001 | likely benign | 21 |
136 | TP53 | rs1057520005 | SNP | missense variant | V/L | 274 | 41 | 0.04 | 59 | benign | 0.058 | 16001 | likely benign | 16 |
137 | TP53 | rs28934576 | SNP | missense variant | R/L | 273 | 1 | 0 | 936 | probably damaging | 0.935 | 28001 | likely benign | 28 |
138 | TP53 | rs28934576 | SNP | missense variant | R/P | 273 | 1 | 0 | 995 | probably damaging | 0.994 | 28001 | likely benign | 28 |
139 | TP53 | rs28934576 | SNP | missense variant | R/H | 273 | 91 | 0.09 | 304 | benign | 0.303 | 24001 | likely benign | 24 |
140 | TP53 | rs121913343 | SNP | missense variant | R/C | 273 | 1 | 0 | 994 | probably damaging | 0.993 | 31001 | likely deleterious | 31 |
141 | TP53 | rs121913343 | SNP | missense variant | R/G | 273 | 1 | 0 | 971 | probably damaging | 0.97 | 28001 | likely benign | 28 |
142 | TP53 | rs121913343 | SNP | missense variant | R/S | 273 | 1 | 0 | 846 | possibly damaging | 0.845 | 27001 | likely benign | 27 |
143 | TP53 | rs876660333 | SNP | missense variant | V/G | 272 | 221 | 0.22 | 1000 | probably damaging | 0.999 | 25001 | likely benign | 25 |
144 | TP53 | rs876660333 | SNP | missense variant | V/A | 272 | 231 | 0.23 | 987 | probably damaging | 0.986 | 25001 | likely benign | 25 |
145 | TP53 | rs876660333 | SNP | missense variant | V/E | 272 | 11 | 0.01 | 1000 | probably damaging | 0.999 | 25001 | likely benign | 25 |
146 | TP53 | rs121912657 | SNP | missense variant | V/L | 272 | 11 | 0.01 | 869 | possibly damaging | 0.868 | 26001 | likely benign | 26 |
147 | TP53 | rs121912657 | SNP | missense variant | V/L | 272 | 11 | 0.01 | 869 | possibly damaging | 0.868 | 26001 | likely benign | 26 |
148 | TP53 | rs121912657 | SNP | missense variant | V/M | 272 | 1 | 0 | 997 | probably damaging | 0.996 | 26001 | likely benign | 26 |
149 | TP53 | rs1555525303 | substitution | missense variant | EV/DM | 271 | - | - | ||||||
150 | TP53 | rs1567548090 | substitution | missense variant | E/L | 271 | 1 | 0 | 1000 | probably damaging | 0.999 | - | ||
151 | TP53 | rs1060501191 | SNP | missense variant | E/K | 271 | 1 | 0 | 987 | probably damaging | 0.986 | 29001 | likely benign | 29 |
152 | TP53 | rs1057519987 | SNP | missense variant | F/L | 270 | 61 | 0.06 | 921 | probably damaging | 0.92 | 31001 | likely deleterious | 31 |
153 | TP53 | rs1057519986 | SNP | missense variant | F/C | 270 | 1 | 0 | 1000 | probably damaging | 0.999 | 31001 | likely deleterious | 31 |
154 | TP53 | rs1057519986 | SNP | missense variant | F/S | 270 | 1 | 0 | 1000 | probably damaging | 0.999 | 32001 | likely deleterious | 32 |
155 | TP53 | rs1057519988 | SNP | missense variant | F/V | 270 | 21 | 0.02 | 978 | probably damaging | 0.977 | 29001 | likely benign | 29 |
156 | TP53 | rs1057519988 | SNP | missense variant | F/L | 270 | 61 | 0.06 | 921 | probably damaging | 0.92 | 31001 | likely deleterious | 31 |
157 | TP53 | rs1057519988 | SNP | missense variant | F/I | 270 | 1 | 0 | 747 | possibly damaging | 0.746 | 29001 | likely benign | 29 |
158 | TP53 | rs587780075 | SNP | missense variant | R/P | 267 | 1 | 0 | 997 | probably damaging | 0.996 | 32001 | likely deleterious | 32 |
159 | TP53 | rs587780075 | SNP | missense variant | R/Q | 267 | 1 | 0 | 966 | probably damaging | 0.965 | 32001 | likely deleterious | 32 |
160 | TP53 | rs55832599 | SNP | missense variant | R/W | 267 | 41 | 0.04 | 646 | possibly damaging | 0.645 | 26001 | likely benign | 26 |
161 | TP53 | rs193920774 | SNP | missense variant | G/V | 266 | 1 | 0 | 982 | probably damaging | 0.981 | 29001 | likely benign | 29 |
162 | TP53 | rs193920774 | SNP | missense variant | G/E | 266 | 1 | 0 | 864 | possibly damaging | 0.863 | 28001 | likely benign | 28 |
163 | TP53 | rs1057519990 | SNP | missense variant | G/R | 266 | 21 | 0.02 | 774 | possibly damaging | 0.773 | 29001 | likely benign | 29 |
164 | TP53 | rs1057519990 | SNP | missense variant | G/R | 266 | 21 | 0.02 | 774 | possibly damaging | 0.773 | 29001 | likely benign | 29 |
165 | TP53 | rs879253942 | SNP | missense variant | L/P | 265 | 1 | 0 | 999 | probably damaging | 0.998 | 32001 | likely deleterious | 32 |
166 | TP53 | rs1555525353 | SNP | missense variant | L/P | 264 | 101 | 0.1 | 150 | benign | 0.149 | 23001 | likely benign | 23 |
167 | TP53 | rs770598448 | SNP | missense variant | N/K | 263 | 331 | 0.33 | 6 | benign | 0.005 | 1 | likely benign | 0 |
168 | TP53 | rs72661119 | SNP | missense variant | N/D | 263 | 231 | 0.23 | 7 | benign | 0.006 | 21001 | likely benign | 21 |
169 | TP53 | rs72661119 | SNP | missense variant | N/H | 263 | 131 | 0.13 | 22 | benign | 0.021 | 21001 | likely benign | 21 |
170 | TP53 | rs1131691025 | SNP | missense variant | G/V | 262 | 1 | 0 | 978 | probably damaging | 0.977 | 26001 | likely benign | 26 |
171 | TP53 | rs200579969 | SNP | missense variant | G/C | 262 | 1 | 0 | 997 | probably damaging | 0.996 | 32001 | likely deleterious | 32 |
172 | TP53 | rs200579969 | SNP | missense variant | G/S | 262 | 1 | 0 | 684 | possibly damaging | 0.683 | 33001 | likely deleterious | 33 |
173 | TP53 | rs786203396 | SNP | missense variant | S/T | 261 | 21 | 0.02 | 36 | benign | 0.035 | 25001 | likely benign | 25 |
174 | TP53 | rs876658916 | SNP | missense variant | S/Y | 260 | 11 | 0.01 | 587 | possibly damaging | 0.586 | 24001 | likely benign | 24 |
175 | TP53 | rs745425759 | SNP | missense variant | D/V | 259 | 51 | 0.05 | 635 | possibly damaging | 0.634 | 25001 | likely benign | 25 |
176 | TP53 | rs745425759 | SNP | missense variant | D/G | 259 | 141 | 0.14 | 38 | benign | 0.037 | 22001 | likely benign | 22 |
177 | TP53 | rs1567548929 | SNP | missense variant | D/Y | 259 | 21 | 0.02 | 155 | benign | 0.154 | 23001 | likely benign | 23 |
178 | TP53 | rs1060501201 | SNP | missense variant | E/G | 258 | 1 | 0 | 1000 | probably damaging | 0.999 | 29001 | likely benign | 29 |
179 | TP53 | rs1060501201 | SNP | missense variant | E/A | 258 | 1 | 0 | 1000 | probably damaging | 0.999 | 28001 | likely benign | 28 |
180 | TP53 | rs121912652 | SNP | missense variant | E/K | 258 | 1 | 0 | 998 | probably damaging | 0.997 | 27001 | likely benign | 27 |
181 | TP53 | rs28934577 | SNP | missense variant | L/R | 257 | 1 | 0 | 1000 | probably damaging | 0.999 | 27001 | likely benign | 27 |
182 | TP53 | rs28934577 | SNP | missense variant | L/P | 257 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
183 | TP53 | rs28934577 | SNP | missense variant | L/Q | 257 | 1 | 0 | 1000 | probably damaging | 0.999 | 27001 | likely benign | 27 |
184 | TP53 | rs587781433 | SNP | missense variant | T/A | 256 | 1 | 0 | 877 | possibly damaging | 0.876 | 24001 | likely benign | 24 |
185 | TP53 | rs587781433 | SNP | missense variant | T/P | 256 | 21 | 0.02 | 721 | possibly damaging | 0.72 | 25001 | likely benign | 25 |
186 | TP53 | rs876659675 | SNP | missense variant | I/S | 255 | 1 | 0 | 996 | probably damaging | 0.995 | 27001 | likely benign | 27 |
187 | TP53 | rs876659675 | SNP | missense variant | I/T | 255 | 1 | 0 | 994 | probably damaging | 0.993 | 25001 | likely benign | 25 |
188 | TP53 | rs876659675 | SNP | missense variant | I/N | 255 | 1 | 0 | 999 | probably damaging | 0.998 | 27001 | likely benign | 27 |
189 | TP53 | rs1057519995 | SNP | missense variant | I/F | 255 | 101 | 0.1 | 986 | probably damaging | 0.985 | 24001 | likely benign | 24 |
190 | TP53 | rs1330865474 | SNP | missense variant | I/S | 254 | 1 | 0 | 1001 | probably damaging | 1 | 26001 | likely benign | 26 |
191 | TP53 | rs746601313 | SNP | missense variant | I/V | 254 | 11 | 0.01 | 770 | possibly damaging | 0.769 | 24001 | likely benign | 24 |
192 | TP53 | rs1555525465 | SNP | missense variant | T/N | 253 | 1 | 0 | 986 | probably damaging | 0.985 | 23001 | likely benign | 23 |
193 | TP53 | rs121912653 | SNP | missense variant | L/P | 252 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
194 | TP53 | rs878854074 | SNP | missense variant | I/M | 251 | 1 | 0 | 997 | probably damaging | 0.996 | 24001 | likely benign | 24 |
195 | TP53 | rs730882027 | SNP | missense variant | I/S | 251 | 1 | 0 | 996 | probably damaging | 0.995 | 28001 | likely benign | 28 |
196 | TP53 | rs730882027 | SNP | missense variant | I/T | 251 | 31 | 0.03 | 997 | probably damaging | 0.996 | 27001 | likely benign | 27 |
197 | TP53 | rs730882027 | SNP | missense variant | I/N | 251 | 21 | 0.02 | 999 | probably damaging | 0.998 | 27001 | likely benign | 27 |
198 | TP53 | rs730882007 | SNP | missense variant | I/L | 251 | 1 | 0 | 928 | probably damaging | 0.927 | 26001 | likely benign | 26 |
199 | TP53 | rs1064794311 | SNP | missense variant | P/L | 250 | 21 | 0.02 | 919 | probably damaging | 0.918 | 28001 | likely benign | 28 |
200 | TP53 | rs28934571 | SNP | missense variant | R/S | 249 | 1 | 0 | 987 | probably damaging | 0.986 | 22001 | likely benign | 22 |
201 | TP53 | rs28934571 | SNP | missense variant | R/S | 249 | 1 | 0 | 987 | probably damaging | 0.986 | 22001 | likely benign | 22 |
202 | TP53 | rs587782329 | SNP | missense variant | R/M | 249 | 1 | 0 | 793 | possibly damaging | 0.792 | 32001 | likely deleterious | 32 |
203 | TP53 | rs587782329 | SNP | missense variant | R/T | 249 | 1 | 0 | 987 | probably damaging | 0.986 | 32001 | likely deleterious | 32 |
204 | TP53 | rs587782329 | SNP | missense variant | R/K | 249 | 31 | 0.03 | 867 | possibly damaging | 0.866 | 32001 | likely deleterious | 32 |
205 | TP53 | rs587782082 | SNP | missense variant | R/W | 249 | 11 | 0.01 | 750 | possibly damaging | 0.749 | 23001 | likely benign | 23 |
206 | TP53 | rs587782082 | SNP | missense variant | R/G | 249 | 1 | 0 | 991 | probably damaging | 0.99 | 23001 | likely benign | 23 |
207 | TP53 | rs11540652 | SNP | missense variant | R/L | 248 | 1 | 0 | 951 | probably damaging | 0.95 | 29001 | likely benign | 29 |
208 | TP53 | rs11540652 | SNP | missense variant | R/P | 248 | 1 | 0 | 992 | probably damaging | 0.991 | 32001 | likely deleterious | 32 |
209 | TP53 | rs11540652 | SNP | missense variant | R/Q | 248 | 21 | 0.02 | 334 | benign | 0.333 | 29001 | likely benign | 29 |
210 | TP53 | rs121912651 | SNP | missense variant | R/W | 248 | 1 | 0 | 997 | probably damaging | 0.996 | 28001 | likely benign | 28 |
211 | TP53 | rs121912651 | SNP | missense variant | R/G | 248 | 21 | 0.02 | 515 | possibly damaging | 0.514 | 27001 | likely benign | 27 |
212 | TP53 | rs1555525498 | substitution | missense variant | NR/NW | 247 | - | - | ||||||
213 | TP53 | rs786201762 | SNP | missense variant | N/I | 247 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
214 | TP53 | rs786201762 | SNP | missense variant | N/S | 247 | 1 | 0 | 999 | probably damaging | 0.998 | 26001 | likely benign | 26 |
215 | TP53 | rs1452189221 | SNP | missense variant | N/D | 247 | 1 | 0 | 1000 | probably damaging | 0.999 | 28001 | likely benign | 28 |
216 | TP53 | rs1019340046 | SNP | missense variant | M/I | 246 | 11 | 0.01 | 913 | probably damaging | 0.912 | 26001 | likely benign | 26 |
217 | TP53 | rs587780074 | SNP | missense variant | M/R | 246 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
218 | TP53 | rs587780074 | SNP | missense variant | M/T | 246 | 1 | 0 | 1001 | probably damaging | 1 | 26001 | likely benign | 26 |
219 | TP53 | rs587780074 | SNP | missense variant | M/K | 246 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
220 | TP53 | rs483352695 | SNP | missense variant | M/L | 246 | 111 | 0.11 | 947 | probably damaging | 0.946 | 26001 | likely benign | 26 |
221 | TP53 | rs483352695 | SNP | missense variant | M/V | 246 | 1 | 0 | 965 | probably damaging | 0.964 | 25001 | likely benign | 25 |
222 | TP53 | rs483352695 | SNP | missense variant | M/L | 246 | 111 | 0.11 | 947 | probably damaging | 0.946 | 26001 | likely benign | 26 |
223 | TP53 | rs121912656 | SNP | missense variant | G/V | 245 | 1 | 0 | 1000 | probably damaging | 0.999 | 26001 | likely benign | 26 |
224 | TP53 | rs121912656 | SNP | missense variant | G/A | 245 | 1 | 0 | 996 | probably damaging | 0.995 | 25001 | likely benign | 25 |
225 | TP53 | rs121912656 | SNP | missense variant | G/D | 245 | 1 | 0 | 1000 | probably damaging | 0.999 | 26001 | likely benign | 26 |
226 | TP53 | rs28934575 | SNP | missense variant | G/C | 245 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
227 | TP53 | rs28934575 | SNP | missense variant | G/R | 245 | 1 | 0 | 990 | probably damaging | 0.989 | 27001 | likely benign | 27 |
228 | TP53 | rs28934575 | SNP | missense variant | G/S | 245 | 1 | 0 | 1000 | probably damaging | 0.999 | 27001 | likely benign | 27 |
229 | TP53 | rs985033810 | SNP | missense variant | G/V | 244 | 1 | 0 | 1000 | probably damaging | 0.999 | 26001 | likely benign | 26 |
230 | TP53 | rs985033810 | SNP | missense variant | G/A | 244 | 1 | 0 | 993 | probably damaging | 0.992 | 25001 | likely benign | 25 |
231 | TP53 | rs985033810 | SNP | missense variant | G/D | 244 | 21 | 0.02 | 934 | probably damaging | 0.933 | 26001 | likely benign | 26 |
232 | TP53 | rs1057519989 | SNP | missense variant | G/C | 244 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
233 | TP53 | rs1057519989 | SNP | missense variant | G/R | 244 | 1 | 0 | 1000 | probably damaging | 0.999 | 27001 | likely benign | 27 |
234 | TP53 | rs1057519989 | SNP | missense variant | G/S | 244 | 1 | 0 | 999 | probably damaging | 0.998 | 27001 | likely benign | 27 |
235 | TP53 | rs730882006 | SNP | missense variant | M/T | 243 | 1 | 0 | 979 | probably damaging | 0.978 | 26001 | likely benign | 26 |
236 | TP53 | rs786203117 | SNP | missense variant | M/L | 243 | 41 | 0.04 | 136 | benign | 0.135 | 25001 | likely benign | 25 |
237 | TP53 | rs786203117 | SNP | missense variant | M/V | 243 | 391 | 0.39 | 747 | possibly damaging | 0.746 | 24001 | likely benign | 24 |
238 | TP53 | rs786203117 | SNP | missense variant | M/L | 243 | 41 | 0.04 | 136 | benign | 0.135 | 25001 | likely benign | 25 |
239 | TP53 | rs375874539 | SNP | missense variant | C/W | 242 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
240 | TP53 | rs121912655 | SNP | missense variant | C/F | 242 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
241 | TP53 | rs121912655 | SNP | missense variant | C/S | 242 | 21 | 0.02 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
242 | TP53 | rs121912655 | SNP | missense variant | C/Y | 242 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
243 | TP53 | rs1057519982 | SNP | missense variant | C/G | 242 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
244 | TP53 | rs1057519982 | SNP | missense variant | C/R | 242 | 1 | 0 | 1001 | probably damaging | 1 | 31001 | likely deleterious | 31 |
245 | TP53 | rs1057519982 | SNP | missense variant | C/S | 242 | 21 | 0.02 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
246 | TP53 | rs28934573 | SNP | missense variant | S/F | 241 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
247 | TP53 | rs28934573 | SNP | missense variant | S/C | 241 | 1 | 0 | 1001 | probably damaging | 1 | 26001 | likely benign | 26 |
248 | TP53 | rs28934573 | SNP | missense variant | S/Y | 241 | 1 | 0 | 1001 | probably damaging | 1 | 26001 | likely benign | 26 |
249 | TP53 | rs1057520002 | SNP | missense variant | S/A | 241 | 1 | 0 | 1000 | probably damaging | 0.999 | 26001 | likely benign | 26 |
250 | TP53 | rs1057520002 | SNP | missense variant | S/P | 241 | 21 | 0.02 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
251 | TP53 | rs764342812 | SNP | missense variant | S/R | 240 | 1 | 0 | 1001 | probably damaging | 1 | 26001 | likely benign | 26 |
252 | TP53 | rs1567549584 | SNP | missense variant | S/G | 240 | 21 | 0.02 | 1001 | probably damaging | 1 | 26001 | likely benign | 26 |
253 | TP53 | rs1057522275 | SNP | missense variant | N/K | 239 | 1 | 0 | 999 | probably damaging | 0.998 | 24001 | likely benign | 24 |
254 | TP53 | rs1057519999 | SNP | missense variant | N/S | 239 | 31 | 0.03 | 786 | possibly damaging | 0.785 | 26001 | likely benign | 26 |
255 | TP53 | rs1057519999 | SNP | missense variant | N/T | 239 | 1 | 0 | 990 | probably damaging | 0.989 | 27001 | likely benign | 27 |
256 | TP53 | rs876660807 | SNP | missense variant | N/D | 239 | 11 | 0.01 | 992 | probably damaging | 0.991 | 28001 | likely benign | 28 |
257 | TP53 | rs193920789 | SNP | missense variant | C/W | 238 | 1 | 0 | 1001 | probably damaging | 1 | 24001 | likely benign | 24 |
258 | TP53 | rs730882005 | SNP | missense variant | C/F | 238 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
259 | TP53 | rs730882005 | SNP | missense variant | C/S | 238 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
260 | TP53 | rs730882005 | SNP | missense variant | C/Y | 238 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
261 | TP53 | rs1057519981 | SNP | missense variant | C/G | 238 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
262 | TP53 | rs1057519981 | SNP | missense variant | C/R | 238 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
263 | TP53 | rs1057519981 | SNP | missense variant | C/S | 238 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
264 | TP53 | rs587782664 | SNP | missense variant | M/I | 237 | 1 | 0 | 661 | possibly damaging | 0.66 | 26001 | likely benign | 26 |
265 | TP53 | rs587782664 | SNP | missense variant | M/I | 237 | 1 | 0 | 661 | possibly damaging | 0.66 | 26001 | likely benign | 26 |
266 | TP53 | rs587782664 | SNP | missense variant | M/I | 237 | 1 | 0 | 661 | possibly damaging | 0.66 | 26001 | likely benign | 26 |
267 | TP53 | rs765848205 | SNP | missense variant | M/R | 237 | 1 | 0 | 987 | probably damaging | 0.986 | 32001 | likely deleterious | 32 |
268 | TP53 | rs765848205 | SNP | missense variant | M/T | 237 | 21 | 0.02 | 814 | possibly damaging | 0.813 | 26001 | likely benign | 26 |
269 | TP53 | rs765848205 | SNP | missense variant | M/K | 237 | 1 | 0 | 980 | probably damaging | 0.979 | 28001 | likely benign | 28 |
270 | TP53 | rs730882004 | SNP | missense variant | M/V | 237 | 1 | 0 | 835 | possibly damaging | 0.834 | 25001 | likely benign | 25 |
271 | TP53 | rs730882026 | SNP | missense variant | Y/C | 236 | 1 | 0 | 987 | probably damaging | 0.986 | 24001 | likely benign | 24 |
272 | TP53 | rs730882026 | SNP | missense variant | Y/S | 236 | 1 | 0 | 997 | probably damaging | 0.996 | 25001 | likely benign | 25 |
273 | TP53 | rs587782289 | SNP | missense variant | Y/D | 236 | 1 | 0 | 999 | probably damaging | 0.998 | 29001 | likely benign | 29 |
274 | TP53 | rs587782289 | SNP | missense variant | Y/H | 236 | 1 | 0 | 987 | probably damaging | 0.986 | 32001 | likely deleterious | 32 |
275 | TP53 | rs587782289 | SNP | missense variant | Y/N | 236 | 1 | 0 | 999 | probably damaging | 0.998 | 29001 | likely benign | 29 |
276 | TP53 | rs144340710 | SNP | missense variant | N/I | 235 | 1 | 0 | 999 | probably damaging | 0.998 | 27001 | likely benign | 27 |
277 | TP53 | rs144340710 | SNP | missense variant | N/S | 235 | 181 | 0.18 | 517 | possibly damaging | 0.516 | 22001 | likely benign | 22 |
278 | TP53 | rs786204145 | SNP | missense variant | N/Y | 235 | 1 | 0 | 999 | probably damaging | 0.998 | 29001 | likely benign | 29 |
279 | TP53 | rs587780073 | SNP | missense variant | Y/C | 234 | 1 | 0 | 993 | probably damaging | 0.992 | 26001 | likely benign | 26 |
280 | TP53 | rs587780073 | SNP | missense variant | Y/S | 234 | 1 | 0 | 961 | probably damaging | 0.96 | 25001 | likely benign | 25 |
281 | TP53 | rs864622237 | SNP | missense variant | Y/D | 234 | 21 | 0.02 | 961 | probably damaging | 0.96 | 24001 | likely benign | 24 |
282 | TP53 | rs864622237 | SNP | missense variant | Y/H | 234 | 1 | 0 | 990 | probably damaging | 0.989 | 27001 | likely benign | 27 |
283 | TP53 | rs864622237 | SNP | missense variant | Y/N | 234 | 1 | 0 | 985 | probably damaging | 0.984 | 27001 | likely benign | 27 |
284 | TP53 | rs879254233 | SNP | missense variant | H/R | 233 | 21 | 0.02 | 59 | benign | 0.058 | 25001 | likely benign | 25 |
285 | TP53 | rs587781589 | SNP | missense variant | I/S | 232 | 1 | 0 | 911 | probably damaging | 0.91 | 31001 | likely deleterious | 31 |
286 | TP53 | rs587781589 | SNP | missense variant | I/T | 232 | 1 | 0 | 482 | possibly damaging | 0.481 | 29001 | likely benign | 29 |
287 | TP53 | rs1555525562 | SNP | missense variant | I/L | 232 | 31 | 0.03 | 90 | benign | 0.089 | 20001 | likely benign | 20 |
288 | TP53 | rs1555525564 | SNP | missense variant | T/I | 231 | 21 | 0.02 | 974 | probably damaging | 0.973 | 29001 | likely benign | 29 |
289 | TP53 | rs1064793603 | SNP | missense variant | C/S | 229 | 381 | 0.38 | 47 | benign | 0.046 | 22001 | likely benign | 22 |
290 | TP53 | rs1064793603 | SNP | missense variant | C/Y | 229 | 1001 | 1 | 66 | benign | 0.065 | 17001 | likely benign | 17 |
291 | TP53 | rs1064794312 | SNP | missense variant | C/R | 229 | 291 | 0.29 | 921 | probably damaging | 0.92 | 24001 | likely benign | 24 |
292 | TP53 | rs970212462 | SNP | missense variant | G/V | 226 | 1 | 0 | 608 | possibly damaging | 0.607 | 24001 | likely benign | 24 |
293 | TP53 | rs746504075 | SNP | missense variant | V/L | 225 | 231 | 0.23 | 28 | benign | 0.027 | 22001 | likely benign | 22 |
294 | TP53 | rs746504075 | SNP | missense variant | V/I | 225 | 31 | 0.03 | 16 | benign | 0.015 | 20001 | likely benign | 20 |
295 | TP53 | rs267605076 | SNP | missense variant | E/D | 224 | 21 | 0.02 | 26 | benign | 0.025 | 33001 | likely deleterious | 33 |
296 | TP53 | rs1131691028 | SNP | missense variant | E/A | 224 | 1 | 0 | 853 | possibly damaging | 0.852 | 35001 | likely deleterious | 35 |
297 | TP53 | rs1555525707 | SNP | missense variant | E/K | 224 | 1 | 0 | 596 | possibly damaging | 0.595 | 28001 | likely benign | 28 |
298 | TP53 | rs138983188 | SNP | missense variant | P/L | 223 | 41 | 0.04 | 846 | possibly damaging | 0.845 | 25001 | likely benign | 25 |
299 | TP53 | rs138983188 | SNP | missense variant | P/H | 223 | 21 | 0.02 | 997 | probably damaging | 0.996 | 27001 | likely benign | 27 |
300 | TP53 | rs146340390 | SNP | missense variant | P/L | 222 | 91 | 0.09 | 22 | benign | 0.021 | 18001 | likely benign | 18 |
301 | TP53 | rs1060501203 | SNP | missense variant | P/S | 222 | 111 | 0.11 | 15 | benign | 0.014 | 16001 | likely benign | 16 |
302 | TP53 | rs1567551121 | SNP | missense variant | E/A | 221 | 11 | 0.01 | 475 | possibly damaging | 0.474 | 27001 | likely benign | 27 |
303 | TP53 | rs786201592 | SNP | missense variant | E/K | 221 | 1 | 0 | 254 | benign | 0.253 | 28001 | likely benign | 28 |
304 | TP53 | rs121912666 | SNP | missense variant | Y/C | 220 | 1 | 0 | 997 | probably damaging | 0.996 | 32001 | likely deleterious | 32 |
305 | TP53 | rs121912666 | SNP | missense variant | Y/S | 220 | 1 | 0 | 838 | possibly damaging | 0.837 | 29001 | likely benign | 29 |
306 | TP53 | rs530941076 | SNP | missense variant | Y/D | 220 | 1 | 0 | 993 | probably damaging | 0.992 | 31001 | likely deleterious | 31 |
307 | TP53 | rs530941076 | SNP | missense variant | Y/H | 220 | 1 | 0 | 997 | probably damaging | 0.996 | 31001 | likely deleterious | 31 |
308 | TP53 | rs530941076 | SNP | missense variant | Y/N | 220 | 1 | 0 | 993 | probably damaging | 0.992 | 31001 | likely deleterious | 31 |
309 | TP53 | rs1420675064 | SNP | missense variant | P/L | 219 | 11 | 0.01 | 993 | probably damaging | 0.992 | 31001 | likely deleterious | 31 |
310 | TP53 | rs879253894 | SNP | missense variant | P/S | 219 | 21 | 0.02 | 718 | possibly damaging | 0.717 | 28001 | likely benign | 28 |
311 | TP53 | rs1555525743 | SNP | missense variant | V/G | 218 | 1 | 0 | 996 | probably damaging | 0.995 | 32001 | likely deleterious | 32 |
312 | TP53 | rs878854072 | SNP | missense variant | V/M | 218 | 1 | 0 | 990 | probably damaging | 0.989 | 25001 | likely benign | 25 |
313 | TP53 | rs35163653 | SNP | missense variant | V/M | 217 | 201 | 0.2 | 388 | benign | 0.387 | 23001 | likely benign | 23 |
314 | TP53 | rs1057520004 | SNP | missense variant | V/G | 216 | 1 | 0 | 999 | probably damaging | 0.998 | 32001 | likely deleterious | 32 |
315 | TP53 | rs1057520004 | SNP | missense variant | V/E | 216 | 1 | 0 | 999 | probably damaging | 0.998 | 31001 | likely deleterious | 31 |
316 | TP53 | rs730882025 | SNP | missense variant | V/L | 216 | 1 | 0 | 942 | probably damaging | 0.941 | 25001 | likely benign | 25 |
317 | TP53 | rs730882025 | SNP | missense variant | V/L | 216 | 1 | 0 | 942 | probably damaging | 0.941 | 25001 | likely benign | 25 |
318 | TP53 | rs730882025 | SNP | missense variant | V/M | 216 | 1 | 0 | 999 | probably damaging | 0.998 | 26001 | likely benign | 26 |
319 | TP53 | rs1057520001 | SNP | missense variant | S/R | 215 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
320 | TP53 | rs587782177 | SNP | missense variant | S/I | 215 | 1 | 0 | 1001 | probably damaging | 1 | 25001 | likely benign | 25 |
321 | TP53 | rs587782177 | SNP | missense variant | S/T | 215 | 1 | 0 | 991 | probably damaging | 0.99 | 24001 | likely benign | 24 |
322 | TP53 | rs587782177 | SNP | missense variant | S/N | 215 | 1 | 0 | 996 | probably damaging | 0.995 | 25001 | likely benign | 25 |
323 | TP53 | rs886039484 | SNP | missense variant | S/G | 215 | 11 | 0.01 | 998 | probably damaging | 0.997 | 26001 | likely benign | 26 |
324 | TP53 | rs886039484 | SNP | missense variant | S/R | 215 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
325 | TP53 | rs587781386 | SNP | missense variant | H/Q | 214 | 1001 | 1 | 286 | benign | 0.285 | 1 | likely benign | 0 |
326 | TP53 | rs1057519992 | SNP | missense variant | H/L | 214 | 11 | 0.01 | 959 | probably damaging | 0.958 | 27001 | likely benign | 27 |
327 | TP53 | rs1057519992 | SNP | missense variant | H/R | 214 | 41 | 0.04 | 942 | probably damaging | 0.941 | 26001 | likely benign | 26 |
328 | TP53 | rs1057519992 | SNP | missense variant | H/P | 214 | 11 | 0.01 | 993 | probably damaging | 0.992 | 27001 | likely benign | 27 |
329 | TP53 | rs876658466 | SNP | missense variant | H/N | 214 | 11 | 0.01 | 972 | probably damaging | 0.971 | 28001 | likely benign | 28 |
330 | TP53 | rs587778720 | SNP | missense variant | R/L | 213 | 1 | 0 | 969 | probably damaging | 0.968 | 29001 | likely benign | 29 |
331 | TP53 | rs587778720 | SNP | missense variant | R/P | 213 | 1 | 0 | 998 | probably damaging | 0.997 | 29001 | likely benign | 29 |
332 | TP53 | rs587778720 | SNP | missense variant | R/Q | 213 | 1 | 0 | 789 | possibly damaging | 0.788 | 29001 | likely benign | 29 |
333 | TP53 | rs397516436 | SNP | missense variant | R/G | 213 | 21 | 0.02 | 987 | probably damaging | 0.986 | 24001 | likely benign | 24 |
334 | TP53 | rs1064795766 | SNP | missense variant | F/I | 212 | 391 | 0.39 | 183 | benign | 0.182 | 16001 | likely benign | 16 |
335 | TP53 | rs1060501198 | SNP | missense variant | T/A | 211 | 1 | 0 | 517 | possibly damaging | 0.516 | 26001 | likely benign | 26 |
336 | TP53 | rs1060501198 | SNP | missense variant | T/P | 211 | 1 | 0 | 952 | probably damaging | 0.951 | 28001 | likely benign | 28 |
337 | TP53 | rs1060501200 | SNP | missense variant | N/Y | 210 | 1001 | 1 | 587 | possibly damaging | 0.586 | 17001 | likely benign | 17 |
338 | TP53 | rs1429743956 | SNP | missense variant | R/G | 209 | 371 | 0.37 | 4 | benign | 0.003 | 17001 | likely benign | 17 |
339 | TP53 | rs1464727668 | SNP | missense variant | D/V | 208 | 11 | 0.01 | 993 | probably damaging | 0.992 | 29001 | likely benign | 29 |
340 | TP53 | rs1464727668 | SNP | missense variant | D/G | 208 | 21 | 0.02 | 980 | probably damaging | 0.979 | 29001 | likely benign | 29 |
341 | TP53 | rs923100890 | SNP | missense variant | D/N | 207 | 21 | 0.02 | 30 | benign | 0.029 | 22001 | likely benign | 22 |
342 | TP53 | rs1555525804 | SNP | missense variant | L/S | 206 | 81 | 0.08 | 27 | benign | 0.026 | 16001 | likely benign | 16 |
343 | TP53 | rs1057520007 | SNP | missense variant | Y/F | 205 | 1 | 0 | 904 | possibly damaging | 0.903 | 26001 | likely benign | 26 |
344 | TP53 | rs1057520007 | SNP | missense variant | Y/C | 205 | 1 | 0 | 990 | probably damaging | 0.989 | 29001 | likely benign | 29 |
345 | TP53 | rs1057520007 | SNP | missense variant | Y/S | 205 | 1 | 0 | 602 | possibly damaging | 0.601 | 27001 | likely benign | 27 |
346 | TP53 | rs1057520008 | SNP | missense variant | Y/D | 205 | 1 | 0 | 957 | probably damaging | 0.956 | 28001 | likely benign | 28 |
347 | TP53 | rs1057520008 | SNP | missense variant | Y/H | 205 | 11 | 0.01 | 465 | possibly damaging | 0.464 | 26001 | likely benign | 26 |
348 | TP53 | rs1057520008 | SNP | missense variant | Y/N | 205 | 1 | 0 | 957 | probably damaging | 0.956 | 27001 | likely benign | 27 |
349 | TP53 | rs1260903787 | SNP | missense variant | E/G | 204 | 11 | 0.01 | 268 | benign | 0.267 | 25001 | likely benign | 25 |
350 | TP53 | rs730882003 | SNP | missense variant | V/L | 203 | 41 | 0.04 | 1 | benign | 0 | 19001 | likely benign | 19 |
351 | TP53 | rs730882003 | SNP | missense variant | V/L | 203 | 41 | 0.04 | 1 | benign | 0 | 19001 | likely benign | 19 |
352 | TP53 | rs730882003 | SNP | missense variant | V/M | 203 | 1 | 0 | 375 | benign | 0.374 | 21001 | likely benign | 21 |
353 | TP53 | rs587778719 | SNP | missense variant | R/L | 202 | 811 | 0.81 | 16 | benign | 0.015 | 4001 | likely benign | 4 |
354 | TP53 | rs587778719 | SNP | missense variant | R/H | 202 | 661 | 0.66 | 4 | benign | 0.003 | 3001 | likely benign | 3 |
355 | TP53 | rs587780072 | SNP | missense variant | R/C | 202 | 111 | 0.11 | 29 | benign | 0.028 | 22001 | likely benign | 22 |
356 | TP53 | rs587780072 | SNP | missense variant | R/G | 202 | 161 | 0.16 | 31 | benign | 0.03 | 23001 | likely benign | 23 |
357 | TP53 | rs730882024 | SNP | missense variant | L/F | 201 | 701 | 0.7 | 34 | benign | 0.033 | 7001 | likely benign | 7 |
358 | TP53 | rs1555525857 | SNP | missense variant | G/V | 199 | 1 | 0 | 977 | probably damaging | 0.976 | 27001 | likely benign | 27 |
359 | TP53 | rs1555525857 | SNP | missense variant | G/E | 199 | 31 | 0.03 | 663 | possibly damaging | 0.662 | 26001 | likely benign | 26 |
360 | TP53 | rs1567551903 | SNP | missense variant | V/E | 197 | 1 | 0 | 997 | probably damaging | 0.996 | 29001 | likely benign | 29 |
361 | TP53 | rs786204041 | SNP | missense variant | V/L | 197 | 31 | 0.03 | 829 | possibly damaging | 0.828 | 24001 | likely benign | 24 |
362 | TP53 | rs786204041 | SNP | missense variant | V/L | 197 | 31 | 0.03 | 829 | possibly damaging | 0.828 | 24001 | likely benign | 24 |
363 | TP53 | rs786204041 | SNP | missense variant | V/M | 197 | 31 | 0.03 | 935 | probably damaging | 0.934 | 24001 | likely benign | 24 |
364 | TP53 | rs483352697 | SNP | missense variant | R/L | 196 | 1 | 0 | 978 | probably damaging | 0.977 | 30001 | likely deleterious | 30 |
365 | TP53 | rs483352697 | SNP | missense variant | R/P | 196 | 1 | 0 | 997 | probably damaging | 0.996 | 29001 | likely benign | 29 |
366 | TP53 | rs483352697 | SNP | missense variant | R/Q | 196 | 61 | 0.06 | 525 | possibly damaging | 0.524 | 25001 | likely benign | 25 |
367 | TP53 | rs397516435 | SNP | missense variant | R/G | 196 | 1 | 0 | 993 | probably damaging | 0.992 | 27001 | likely benign | 27 |
368 | TP53 | rs1057519994 | SNP | missense variant | I/M | 195 | 21 | 0.02 | 911 | probably damaging | 0.91 | 25001 | likely benign | 25 |
369 | TP53 | rs760043106 | SNP | missense variant | I/S | 195 | 1 | 0 | 992 | probably damaging | 0.991 | 29001 | likely benign | 29 |
370 | TP53 | rs760043106 | SNP | missense variant | I/T | 195 | 1 | 0 | 938 | probably damaging | 0.937 | 27001 | likely benign | 27 |
371 | TP53 | rs760043106 | SNP | missense variant | I/N | 195 | 1 | 0 | 997 | probably damaging | 0.996 | 29001 | likely benign | 29 |
372 | TP53 | rs942158624 | SNP | missense variant | I/F | 195 | 1 | 0 | 986 | probably damaging | 0.985 | 27001 | likely benign | 27 |
373 | TP53 | rs1057519998 | SNP | missense variant | L/R | 194 | 1 | 0 | 1001 | probably damaging | 1 | 30001 | likely deleterious | 30 |
374 | TP53 | rs1057519998 | SNP | missense variant | L/P | 194 | 1 | 0 | 1001 | probably damaging | 1 | 31001 | likely deleterious | 31 |
375 | TP53 | rs1057519998 | SNP | missense variant | L/H | 194 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
376 | TP53 | rs587780071 | SNP | missense variant | L/F | 194 | 51 | 0.05 | 973 | probably damaging | 0.972 | 28001 | likely benign | 28 |
377 | TP53 | rs786201838 | SNP | missense variant | H/L | 193 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
378 | TP53 | rs786201838 | SNP | missense variant | H/R | 193 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
379 | TP53 | rs786201838 | SNP | missense variant | H/P | 193 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
380 | TP53 | rs876658468 | SNP | missense variant | H/Y | 193 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
381 | TP53 | rs876658468 | SNP | missense variant | H/D | 193 | 1 | 0 | 1001 | probably damaging | 1 | 32001 | likely deleterious | 32 |
382 | TP53 | rs876658468 | SNP | missense variant | H/N | 193 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
383 | TP53 | rs730882002 | SNP | missense variant | Q/R | 192 | 61 | 0.06 | 73 | benign | 0.072 | 24001 | likely benign | 24 |
384 | TP53 | rs587778718 | SNP | missense variant | P/L | 191 | 1 | 0 | 950 | probably damaging | 0.949 | 29001 | likely benign | 29 |
385 | TP53 | rs587778718 | SNP | missense variant | P/R | 191 | 221 | 0.22 | 967 | probably damaging | 0.966 | 23001 | likely benign | 23 |
386 | TP53 | rs587778718 | SNP | missense variant | P/H | 191 | 1 | 0 | 979 | probably damaging | 0.978 | 28001 | likely benign | 28 |
387 | TP53 | rs868590738 | SNP | missense variant | P/S | 191 | 41 | 0.04 | 228 | benign | 0.227 | 23001 | likely benign | 23 |
388 | TP53 | rs876660825 | SNP | missense variant | P/L | 190 | 51 | 0.05 | 862 | possibly damaging | 0.861 | 27001 | likely benign | 27 |
389 | TP53 | rs876660825 | SNP | missense variant | P/R | 190 | 31 | 0.03 | 998 | probably damaging | 0.997 | 28001 | likely benign | 28 |
390 | TP53 | rs876660254 | SNP | missense variant | P/T | 190 | 11 | 0.01 | 988 | probably damaging | 0.987 | 26001 | likely benign | 26 |
391 | TP53 | rs121912665 | SNP | missense variant | A/V | 189 | 31 | 0.03 | 771 | possibly damaging | 0.77 | 26001 | likely benign | 26 |
392 | TP53 | rs1555525921 | SNP | missense variant | A/S | 189 | 51 | 0.05 | 971 | probably damaging | 0.97 | 27001 | likely benign | 27 |
393 | TP53 | rs1199893366 | SNP | missense variant | L/P | 188 | 191 | 0.19 | 206 | benign | 0.205 | 22001 | likely benign | 22 |
394 | TP53 | rs1064795841 | SNP | missense variant | G/D | 187 | 91 | 0.09 | 224 | benign | 0.223 | 9001 | likely benign | 9 |
395 | TP53 | rs776167460 | SNP | missense variant | G/S | 187 | 141 | 0.14 | 334 | benign | 0.333 | 23001 | likely benign | 23 |
396 | TP53 | rs375275361 | SNP | missense variant | D/E | 186 | 211 | 0.21 | 322 | benign | 0.321 | 13001 | likely benign | 13 |
397 | TP53 | rs1060501206 | SNP | missense variant | D/N | 186 | 101 | 0.1 | 447 | possibly damaging | 0.446 | 22001 | likely benign | 22 |
398 | TP53 | rs150607408 | SNP | missense variant | S/N | 185 | 921 | 0.92 | 2 | benign | 0.001 | 2001 | likely benign | 2 |
399 | TP53 | rs1060501209 | SNP | missense variant | D/G | 184 | 41 | 0.04 | 221 | benign | 0.22 | 23001 | likely benign | 23 |
400 | TP53 | rs72661117 | SNP | missense variant | D/N | 184 | 271 | 0.27 | 180 | benign | 0.179 | 16001 | likely benign | 16 |
401 | TP53 | rs1555525970 | SNP | missense variant | S/L | 183 | 121 | 0.12 | 264 | benign | 0.263 | 21001 | likely benign | 21 |
402 | TP53 | rs1064796257 | SNP | missense variant | C/W | 182 | 31 | 0.03 | 884 | possibly damaging | 0.883 | 23001 | likely benign | 23 |
403 | TP53 | rs397514495 | SNP | missense variant | R/L | 181 | 341 | 0.34 | 869 | possibly damaging | 0.868 | 24001 | likely benign | 24 |
404 | TP53 | rs397514495 | SNP | missense variant | R/H | 181 | 81 | 0.08 | 969 | probably damaging | 0.968 | 25001 | likely benign | 25 |
405 | TP53 | rs587782596 | SNP | missense variant | R/C | 181 | 131 | 0.13 | 308 | benign | 0.307 | 24001 | likely benign | 24 |
406 | TP53 | rs587782596 | SNP | missense variant | R/S | 181 | 351 | 0.35 | 978 | probably damaging | 0.977 | 23001 | likely benign | 23 |
407 | TP53 | rs879253911 | SNP | missense variant | E/K | 180 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
408 | TP53 | rs876660821 | SNP | missense variant | H/Q | 179 | 1 | 0 | 843 | possibly damaging | 0.842 | 12001 | likely benign | 12 |
409 | TP53 | rs876660821 | SNP | missense variant | H/Q | 179 | 1 | 0 | 843 | possibly damaging | 0.842 | 12001 | likely benign | 12 |
410 | TP53 | rs1057519991 | SNP | missense variant | H/L | 179 | 71 | 0.07 | 496 | possibly damaging | 0.495 | 22001 | likely benign | 22 |
411 | TP53 | rs1057519991 | SNP | missense variant | H/R | 179 | 1 | 0 | 983 | probably damaging | 0.982 | 24001 | likely benign | 24 |
412 | TP53 | rs1057519991 | SNP | missense variant | H/P | 179 | 1 | 0 | 998 | probably damaging | 0.997 | 24001 | likely benign | 24 |
413 | TP53 | rs587780070 | SNP | missense variant | H/Y | 179 | 1 | 0 | 995 | probably damaging | 0.994 | 27001 | likely benign | 27 |
414 | TP53 | rs587780070 | SNP | missense variant | H/D | 179 | 1 | 0 | 995 | probably damaging | 0.994 | 27001 | likely benign | 27 |
415 | TP53 | rs587780070 | SNP | missense variant | H/N | 179 | 1 | 0 | 995 | probably damaging | 0.994 | 26001 | likely benign | 26 |
416 | TP53 | rs1555526001 | SNP | missense variant | H/Q | 178 | 1 | 0 | 1000 | probably damaging | 0.999 | 24001 | likely benign | 24 |
417 | TP53 | rs1555526004 | SNP | missense variant | H/P | 178 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
418 | TP53 | rs1064795203 | SNP | missense variant | H/D | 178 | 1 | 0 | 1001 | probably damaging | 1 | 25001 | likely benign | 25 |
419 | TP53 | rs1064795203 | SNP | missense variant | H/N | 178 | 411 | 0.41 | 1001 | probably damaging | 1 | 25001 | likely benign | 25 |
420 | TP53 | rs751477326 | SNP | missense variant | P/L | 177 | 1 | 0 | 989 | probably damaging | 0.988 | 29001 | likely benign | 29 |
421 | TP53 | rs751477326 | SNP | missense variant | P/R | 177 | 21 | 0.02 | 803 | possibly damaging | 0.802 | 27001 | likely benign | 27 |
422 | TP53 | rs147002414 | SNP | missense variant | P/S | 177 | 1 | 0 | 947 | probably damaging | 0.946 | 27001 | likely benign | 27 |
423 | TP53 | rs147002414 | SNP | missense variant | P/T | 177 | 1 | 0 | 972 | probably damaging | 0.971 | 26001 | likely benign | 26 |
424 | TP53 | rs1057519980 | SNP | missense variant | C/W | 176 | 1 | 0 | 1001 | probably damaging | 1 | 22001 | likely benign | 22 |
425 | TP53 | rs1567552847 | substitution | missense variant | C/R | 176 | 1 | 0 | 1000 | probably damaging | 0.999 | 29001 | likely benign | 29 |
426 | TP53 | rs786202962 | SNP | missense variant | C/F | 176 | 1 | 0 | 997 | probably damaging | 0.996 | 27001 | likely benign | 27 |
427 | TP53 | rs786202962 | SNP | missense variant | C/Y | 176 | 1 | 0 | 996 | probably damaging | 0.995 | 27001 | likely benign | 27 |
428 | TP53 | rs967461896 | SNP | missense variant | C/G | 176 | 1 | 0 | 999 | probably damaging | 0.998 | 29001 | likely benign | 29 |
429 | TP53 | rs967461896 | SNP | missense variant | C/R | 176 | 1 | 0 | 1000 | probably damaging | 0.999 | 29001 | likely benign | 29 |
430 | TP53 | rs967461896 | SNP | missense variant | C/S | 176 | 1 | 0 | 933 | probably damaging | 0.932 | 27001 | likely benign | 27 |
431 | TP53 | rs28934578 | SNP | missense variant | R/L | 175 | 1 | 0 | 707 | possibly damaging | 0.706 | 28001 | likely benign | 28 |
432 | TP53 | rs28934578 | SNP | missense variant | R/H | 175 | 81 | 0.08 | 110 | benign | 0.109 | 23001 | likely benign | 23 |
433 | TP53 | rs138729528 | SNP | missense variant | R/C | 175 | 1 | 0 | 296 | benign | 0.295 | 32001 | likely deleterious | 32 |
434 | TP53 | rs138729528 | SNP | missense variant | R/G | 175 | 1 | 0 | 965 | probably damaging | 0.964 | 32001 | likely deleterious | 32 |
435 | TP53 | rs1064796681 | SNP | missense variant | R/K | 174 | 841 | 0.84 | 20 | benign | 0.019 | 14001 | likely benign | 14 |
436 | TP53 | rs864622115 | SNP | missense variant | R/G | 174 | 1 | 0 | 825 | possibly damaging | 0.824 | 24001 | likely benign | 24 |
437 | TP53 | rs1057519747 | SNP | missense variant | V/G | 173 | 1 | 0 | 1000 | probably damaging | 0.999 | 28001 | likely benign | 28 |
438 | TP53 | rs1057519747 | SNP | missense variant | V/A | 173 | 1 | 0 | 997 | probably damaging | 0.996 | 25001 | likely benign | 25 |
439 | TP53 | rs1057519747 | SNP | missense variant | V/E | 173 | 1 | 0 | 999 | probably damaging | 0.998 | 26001 | likely benign | 26 |
440 | TP53 | rs876660754 | SNP | missense variant | V/L | 173 | 21 | 0.02 | 649 | possibly damaging | 0.648 | 24001 | likely benign | 24 |
441 | TP53 | rs876660754 | SNP | missense variant | V/M | 173 | 21 | 0.02 | 974 | probably damaging | 0.973 | 24001 | likely benign | 24 |
442 | TP53 | rs1131691021 | SNP | missense variant | V/G | 172 | 1 | 0 | 988 | probably damaging | 0.987 | 25001 | likely benign | 25 |
443 | TP53 | rs1131691021 | SNP | missense variant | V/A | 172 | 21 | 0.02 | 964 | probably damaging | 0.963 | 24001 | likely benign | 24 |
444 | TP53 | rs1131691043 | SNP | missense variant | V/F | 172 | 1 | 0 | 974 | probably damaging | 0.973 | 23001 | likely benign | 23 |
445 | TP53 | rs587781845 | SNP | missense variant | E/K | 171 | 21 | 0.02 | 992 | probably damaging | 0.991 | 24001 | likely benign | 24 |
446 | TP53 | rs779000871 | SNP | missense variant | T/M | 170 | 81 | 0.08 | 289 | benign | 0.288 | 21001 | likely benign | 21 |
447 | TP53 | rs779000871 | SNP | missense variant | T/R | 170 | 1 | 0 | 912 | probably damaging | 0.911 | 26001 | likely benign | 26 |
448 | TP53 | rs587780729 | SNP | missense variant | T/A | 170 | 621 | 0.62 | 13 | benign | 0.012 | 15001 | likely benign | 15 |
449 | TP53 | rs1567553114 | SNP | missense variant | M/R | 169 | 1 | 0 | 584 | possibly damaging | 0.583 | 23001 | likely benign | 23 |
450 | TP53 | rs867114783 | SNP | missense variant | H/R | 168 | 1 | 0 | 904 | possibly damaging | 0.903 | 23001 | likely benign | 23 |
451 | TP53 | rs1319163924 | SNP | missense variant | Q/P | 167 | 1 | 0 | 775 | possibly damaging | 0.774 | 24001 | likely benign | 24 |
452 | TP53 | rs1555526101 | SNP | missense variant | S/L | 166 | 91 | 0.09 | 163 | benign | 0.162 | 18001 | likely benign | 18 |
453 | TP53 | rs730882001 | SNP | missense variant | Q/K | 165 | 1001 | 1 | 1 | benign | 0 | 13001 | likely benign | 13 |
454 | TP53 | rs1131691034 | SNP | missense variant | K/N | 164 | 1 | 0 | 991 | probably damaging | 0.99 | 23001 | likely benign | 23 |
455 | TP53 | rs879254249 | SNP | missense variant | K/E | 164 | 1 | 0 | 940 | probably damaging | 0.939 | 25001 | likely benign | 25 |
456 | TP53 | rs148924904 | SNP | missense variant | Y/C | 163 | 21 | 0.02 | 890 | possibly damaging | 0.889 | 24001 | likely benign | 24 |
457 | TP53 | rs786203436 | SNP | missense variant | Y/D | 163 | 1 | 0 | 1001 | probably damaging | 1 | 26001 | likely benign | 26 |
458 | TP53 | rs786203436 | SNP | missense variant | Y/H | 163 | 1 | 0 | 999 | probably damaging | 0.998 | 26001 | likely benign | 26 |
459 | TP53 | rs786203436 | SNP | missense variant | Y/N | 163 | 1 | 0 | 1001 | probably damaging | 1 | 25001 | likely benign | 25 |
460 | TP53 | rs587780069 | SNP | missense variant | I/S | 162 | 31 | 0.03 | 453 | possibly damaging | 0.452 | 26001 | likely benign | 26 |
461 | TP53 | rs1064795691 | SNP | missense variant | A/D | 161 | 1 | 0 | 1001 | probably damaging | 1 | 26001 | likely benign | 26 |
462 | TP53 | rs193920817 | SNP | missense variant | A/T | 161 | 11 | 0.01 | 1001 | probably damaging | 1 | 24001 | likely benign | 24 |
463 | TP53 | rs772354334 | SNP | missense variant | M/I | 160 | 41 | 0.04 | 55 | benign | 0.054 | 20001 | likely benign | 20 |
464 | TP53 | rs377274728 | SNP | missense variant | M/L | 160 | 81 | 0.08 | 11 | benign | 0.01 | 18001 | likely benign | 18 |
465 | TP53 | rs377274728 | SNP | missense variant | M/V | 160 | 41 | 0.04 | 55 | benign | 0.054 | 17001 | likely benign | 17 |
466 | TP53 | rs730882022 | substitution | missense variant | A/F | 159 | 1 | 0 | 997 | probably damaging | 0.996 | - | ||
467 | TP53 | rs1555526131 | SNP | missense variant | A/V | 159 | 1 | 0 | 911 | probably damaging | 0.91 | 24001 | likely benign | 24 |
468 | TP53 | rs730882000 | SNP | missense variant | A/P | 159 | 1 | 0 | 995 | probably damaging | 0.994 | 24001 | likely benign | 24 |
469 | TP53 | rs730882000 | SNP | missense variant | A/T | 159 | 111 | 0.11 | 333 | benign | 0.332 | 22001 | likely benign | 22 |
470 | TP53 | rs1567553501 | substitution | missense variant | R/L | 158 | 1 | 0 | 992 | probably damaging | 0.991 | 25001 | likely benign | 25 |
471 | TP53 | rs587782144 | SNP | missense variant | R/L | 158 | 1 | 0 | 992 | probably damaging | 0.991 | 25001 | likely benign | 25 |
472 | TP53 | rs587782144 | SNP | missense variant | R/P | 158 | 1 | 0 | 999 | probably damaging | 0.998 | 25001 | likely benign | 25 |
473 | TP53 | rs587782144 | SNP | missense variant | R/H | 158 | 91 | 0.09 | 449 | possibly damaging | 0.448 | 23001 | likely benign | 23 |
474 | TP53 | rs587780068 | SNP | missense variant | R/C | 158 | 1 | 0 | 1000 | probably damaging | 0.999 | 25001 | likely benign | 25 |
475 | TP53 | rs1131691023 | SNP | missense variant | V/A | 157 | 1 | 0 | 927 | probably damaging | 0.926 | 25001 | likely benign | 25 |
476 | TP53 | rs1131691023 | SNP | missense variant | V/D | 157 | 1 | 0 | 999 | probably damaging | 0.998 | 25001 | likely benign | 25 |
477 | TP53 | rs121912654 | SNP | missense variant | V/F | 157 | 1 | 0 | 984 | probably damaging | 0.983 | 22001 | likely benign | 22 |
478 | TP53 | rs121912654 | SNP | missense variant | V/I | 157 | 751 | 0.75 | 42 | benign | 0.041 | 15001 | likely benign | 15 |
479 | TP53 | rs371524413 | SNP | missense variant | R/P | 156 | 121 | 0.12 | 859 | possibly damaging | 0.858 | 22001 | likely benign | 22 |
480 | TP53 | rs371524413 | SNP | missense variant | R/H | 156 | 261 | 0.26 | 21 | benign | 0.02 | 20001 | likely benign | 20 |
481 | TP53 | rs563378859 | SNP | missense variant | R/C | 156 | 231 | 0.23 | 19 | benign | 0.018 | 17001 | likely benign | 17 |
482 | TP53 | rs786202752 | SNP | missense variant | T/S | 155 | 701 | 0.7 | 7 | benign | 0.006 | 4001 | likely benign | 4 |
483 | TP53 | rs786202752 | SNP | missense variant | T/N | 155 | 1 | 0 | 616 | possibly damaging | 0.615 | 14001 | likely benign | 14 |
484 | TP53 | rs772683278 | SNP | missense variant | T/A | 155 | 921 | 0.92 | 4 | benign | 0.003 | 5001 | likely benign | 5 |
485 | TP53 | rs762846821 | SNP | missense variant | G/V | 154 | 1 | 0 | 980 | probably damaging | 0.979 | 22001 | likely benign | 22 |
486 | TP53 | rs762846821 | SNP | missense variant | G/D | 154 | 31 | 0.03 | 283 | benign | 0.282 | 17001 | likely benign | 17 |
487 | TP53 | rs137852789 | SNP | missense variant | G/R | 154 | 1 | 0 | 986 | probably damaging | 0.985 | 22001 | likely benign | 22 |
488 | TP53 | rs137852789 | SNP | missense variant | G/S | 154 | 101 | 0.1 | 309 | benign | 0.308 | 18001 | likely benign | 18 |
489 | TP53 | rs1064795860 | SNP | missense variant | P/S | 153 | 51 | 0.05 | 326 | benign | 0.325 | 7001 | likely benign | 7 |
490 | TP53 | rs587782705 | SNP | missense variant | P/L | 152 | 41 | 0.04 | 820 | possibly damaging | 0.819 | 24001 | likely benign | 24 |
491 | TP53 | rs767328513 | SNP | missense variant | P/S | 152 | 1 | 0 | 990 | probably damaging | 0.989 | 25001 | likely benign | 25 |
492 | TP53 | rs1057520000 | SNP | missense variant | P/R | 151 | 1 | 0 | 998 | probably damaging | 0.997 | 25001 | likely benign | 25 |
493 | TP53 | rs1057520000 | SNP | missense variant | P/H | 151 | 1 | 0 | 942 | probably damaging | 0.941 | 25001 | likely benign | 25 |
494 | TP53 | rs28934874 | SNP | missense variant | P/S | 151 | 11 | 0.01 | 892 | possibly damaging | 0.891 | 25001 | likely benign | 25 |
495 | TP53 | rs28934874 | SNP | missense variant | P/A | 151 | 11 | 0.01 | 922 | probably damaging | 0.921 | 24001 | likely benign | 24 |
496 | TP53 | rs28934874 | SNP | missense variant | P/T | 151 | 1 | 0 | 892 | possibly damaging | 0.891 | 24001 | likely benign | 24 |
497 | TP53 | rs1555526214 | SNP | missense variant | S/F | 149 | 91 | 0.09 | 101 | benign | 0.1 | 19001 | likely benign | 19 |
498 | TP53 | rs1046611742 | SNP | missense variant | D/A | 148 | 321 | 0.32 | 1 | benign | 0 | 3001 | likely benign | 3 |
499 | TP53 | rs1131691007 | SNP | missense variant | D/Y | 148 | 11 | 0.01 | 605 | possibly damaging | 0.604 | 21001 | likely benign | 21 |
500 | TP53 | rs1131691007 | SNP | missense variant | D/N | 148 | 351 | 0.35 | 1 | benign | 0 | 10001 | likely benign | 10 |
501 | TP53 | rs1453167097 | SNP | missense variant | V/G | 147 | 1 | 0 | 931 | probably damaging | 0.93 | 25001 | likely benign | 25 |
502 | TP53 | rs1555526226 | SNP | missense variant | V/I | 147 | 11 | 0.01 | 79 | benign | 0.078 | 19001 | likely benign | 19 |
503 | TP53 | rs786203064 | SNP | missense variant | W/G | 146 | 341 | 0.34 | 341 | benign | 0.34 | 19001 | likely benign | 19 |
504 | TP53 | rs587782197 | SNP | missense variant | L/P | 145 | 61 | 0.06 | 159 | benign | 0.158 | 23001 | likely benign | 23 |
505 | TP53 | rs587782197 | SNP | missense variant | L/Q | 145 | 1 | 0 | 866 | possibly damaging | 0.865 | 26001 | likely benign | 26 |
506 | TP53 | rs786201419 | SNP | missense variant | Q/H | 144 | 21 | 0.02 | 802 | possibly damaging | 0.801 | 23001 | likely benign | 23 |
507 | TP53 | rs786203071 | SNP | missense variant | Q/L | 144 | 81 | 0.08 | 469 | possibly damaging | 0.468 | 23001 | likely benign | 23 |
508 | TP53 | rs786203071 | SNP | missense variant | Q/P | 144 | 1 | 0 | 996 | probably damaging | 0.995 | 25001 | likely benign | 25 |
509 | TP53 | rs1555526241 | SNP | missense variant | V/G | 143 | 1 | 0 | 1000 | probably damaging | 0.999 | 26001 | likely benign | 26 |
510 | TP53 | rs587782620 | SNP | missense variant | V/L | 143 | 51 | 0.05 | 890 | possibly damaging | 0.889 | 22001 | likely benign | 22 |
511 | TP53 | rs587782620 | SNP | missense variant | V/M | 143 | 1 | 0 | 998 | probably damaging | 0.997 | 24001 | likely benign | 24 |
512 | TP53 | rs779196500 | SNP | missense variant | P/L | 142 | 21 | 0.02 | 997 | probably damaging | 0.996 | 28001 | likely benign | 28 |
513 | TP53 | rs1057519977 | SNP | missense variant | C/W | 141 | 1 | 0 | 1000 | probably damaging | 0.999 | 24001 | likely benign | 24 |
514 | TP53 | rs587781288 | SNP | missense variant | C/F | 141 | 1 | 0 | 991 | probably damaging | 0.99 | 26001 | likely benign | 26 |
515 | TP53 | rs587781288 | SNP | missense variant | C/Y | 141 | 1 | 0 | 867 | possibly damaging | 0.866 | 27001 | likely benign | 27 |
516 | TP53 | rs1057519978 | SNP | missense variant | C/G | 141 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
517 | TP53 | rs1057519978 | SNP | missense variant | C/R | 141 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
518 | TP53 | rs1057519978 | SNP | missense variant | C/S | 141 | 111 | 0.11 | 1000 | probably damaging | 0.999 | 24001 | likely benign | 24 |
519 | TP53 | rs786202561 | SNP | missense variant | T/N | 140 | 1 | 0 | 880 | possibly damaging | 0.879 | 26001 | likely benign | 26 |
520 | TP53 | rs1567554121 | SNP | missense variant | K/N | 139 | 11 | 0.01 | 853 | possibly damaging | 0.852 | 23001 | likely benign | 23 |
521 | TP53 | rs1212996409 | SNP | missense variant | K/E | 139 | 1 | 0 | 972 | probably damaging | 0.971 | 28001 | likely benign | 28 |
522 | TP53 | rs750600586 | SNP | missense variant | A/V | 138 | 21 | 0.02 | 981 | probably damaging | 0.98 | 25001 | likely benign | 25 |
523 | TP53 | rs750600586 | SNP | missense variant | A/D | 138 | 1 | 0 | 988 | probably damaging | 0.987 | 26001 | likely benign | 26 |
524 | TP53 | rs28934875 | SNP | missense variant | A/P | 138 | 1 | 0 | 995 | probably damaging | 0.994 | 28001 | likely benign | 28 |
525 | TP53 | rs758781593 | SNP | missense variant | Q/H | 136 | 1 | 0 | 992 | probably damaging | 0.991 | 23001 | likely benign | 23 |
526 | TP53 | rs758781593 | SNP | missense variant | Q/H | 136 | 1 | 0 | 992 | probably damaging | 0.991 | 23001 | likely benign | 23 |
527 | TP53 | rs1567554216 | SNP | missense variant | Q/P | 136 | 1 | 0 | 997 | probably damaging | 0.996 | 28001 | likely benign | 28 |
528 | TP53 | rs1555526268 | SNP | missense variant | Q/E | 136 | 1 | 0 | 945 | probably damaging | 0.944 | 26001 | likely benign | 26 |
529 | TP53 | rs1057519976 | SNP | missense variant | C/W | 135 | 1 | 0 | 1001 | probably damaging | 1 | 25001 | likely benign | 25 |
530 | TP53 | rs587781991 | SNP | missense variant | C/F | 135 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
531 | TP53 | rs587781991 | SNP | missense variant | C/Y | 135 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
532 | TP53 | rs1057519975 | SNP | missense variant | C/G | 135 | 11 | 0.01 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
533 | TP53 | rs1057519975 | SNP | missense variant | C/R | 135 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
534 | TP53 | rs1057519975 | SNP | missense variant | C/S | 135 | 1 | 0 | 1001 | probably damaging | 1 | 31001 | likely deleterious | 31 |
535 | TP53 | rs780442292 | SNP | missense variant | F/C | 134 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
536 | TP53 | rs267605077 | SNP | missense variant | F/L | 134 | 1 | 0 | 994 | probably damaging | 0.993 | 29001 | likely benign | 29 |
537 | TP53 | rs267605077 | SNP | missense variant | F/I | 134 | 1 | 0 | 999 | probably damaging | 0.998 | 29001 | likely benign | 29 |
538 | TP53 | rs1064795139 | SNP | missense variant | M/I | 133 | 1 | 0 | 8 | benign | 0.007 | 18001 | likely benign | 18 |
539 | TP53 | rs28934873 | SNP | missense variant | M/T | 133 | 1 | 0 | 125 | benign | 0.124 | 23001 | likely benign | 23 |
540 | TP53 | rs1057280220 | SNP | missense variant | M/V | 133 | 11 | 0.01 | 4 | benign | 0.003 | 21001 | likely benign | 21 |
541 | TP53 | rs866775781 | SNP | missense variant | K/N | 132 | 11 | 0.01 | 999 | probably damaging | 0.998 | 25001 | likely benign | 25 |
542 | TP53 | rs866775781 | SNP | missense variant | K/N | 132 | 11 | 0.01 | 999 | probably damaging | 0.998 | 25001 | likely benign | 25 |
543 | TP53 | rs1057519996 | SNP | missense variant | K/M | 132 | 41 | 0.04 | 844 | possibly damaging | 0.843 | 28001 | likely benign | 28 |
544 | TP53 | rs1057519996 | SNP | missense variant | K/R | 132 | 1 | 0 | 989 | probably damaging | 0.988 | 33001 | likely deleterious | 33 |
545 | TP53 | rs1057519996 | SNP | missense variant | K/T | 132 | 1 | 0 | 996 | probably damaging | 0.995 | 32001 | likely deleterious | 32 |
546 | TP53 | rs747342068 | SNP | missense variant | K/E | 132 | 1 | 0 | 990 | probably damaging | 0.989 | 31001 | likely deleterious | 31 |
547 | TP53 | rs747342068 | SNP | missense variant | K/Q | 132 | 1 | 0 | 980 | probably damaging | 0.979 | 28001 | likely benign | 28 |
548 | TP53 | rs769270327 | SNP | missense variant | N/K | 131 | 411 | 0.41 | 999 | probably damaging | 0.998 | 24001 | likely benign | 24 |
549 | TP53 | rs1131691037 | SNP | missense variant | N/I | 131 | 1 | 0 | 999 | probably damaging | 0.998 | 28001 | likely benign | 28 |
550 | TP53 | rs587782160 | SNP | missense variant | N/Y | 131 | 1 | 0 | 1000 | probably damaging | 0.999 | 27001 | likely benign | 27 |
551 | TP53 | rs1131691013 | SNP | missense variant | L/P | 130 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
552 | TP53 | rs863224683 | SNP | missense variant | L/F | 130 | 1 | 0 | 1001 | probably damaging | 1 | 26001 | likely benign | 26 |
553 | TP53 | rs863224683 | SNP | missense variant | L/V | 130 | 51 | 0.05 | 999 | probably damaging | 0.998 | 25001 | likely benign | 25 |
554 | TP53 | rs137852792 | SNP | missense variant | A/V | 129 | 291 | 0.29 | 1 | benign | 0 | 1 | likely benign | 0 |
555 | TP53 | rs137852792 | SNP | missense variant | A/G | 129 | 381 | 0.38 | 1 | benign | 0 | 1 | likely benign | 0 |
556 | TP53 | rs1438095083 | SNP | missense variant | A/T | 129 | 571 | 0.57 | 1 | benign | 0 | 1 | likely benign | 0 |
557 | TP53 | rs1555526327 | SNP | missense variant | P/T | 128 | 181 | 0.18 | 199 | benign | 0.198 | 16001 | likely benign | 16 |
558 | TP53 | rs730881999 | SNP | missense variant | S/F | 127 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
559 | TP53 | rs730881999 | SNP | missense variant | S/C | 127 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
560 | TP53 | rs1555526335 | SNP | missense variant | Y/C | 126 | 1 | 0 | 1001 | probably damaging | 1 | 32001 | likely deleterious | 32 |
561 | TP53 | rs886039483 | SNP | missense variant | Y/D | 126 | 1 | 0 | 1000 | probably damaging | 0.999 | 32001 | likely deleterious | 32 |
562 | TP53 | rs886039483 | SNP | missense variant | Y/N | 126 | 1 | 0 | 1000 | probably damaging | 0.999 | 32001 | likely deleterious | 32 |
563 | TP53 | rs786201057 | SNP | missense variant | T/M | 125 | 41 | 0.04 | 976 | probably damaging | 0.975 | 32001 | likely deleterious | 32 |
564 | TP53 | rs786201057 | SNP | missense variant | T/R | 125 | 1 | 0 | 1000 | probably damaging | 0.999 | 32001 | likely deleterious | 32 |
565 | TP53 | rs786201057 | SNP | missense variant | T/K | 125 | 1 | 0 | 997 | probably damaging | 0.996 | 31001 | likely deleterious | 31 |
566 | TP53 | rs1057520003 | SNP | missense variant | T/P | 125 | 1 | 0 | 999 | probably damaging | 0.998 | 31001 | likely deleterious | 31 |
567 | TP53 | rs730881997 | SNP | missense variant | C/G | 124 | 81 | 0.08 | 974 | probably damaging | 0.973 | 24001 | likely benign | 24 |
568 | TP53 | rs730881997 | SNP | missense variant | C/S | 124 | 491 | 0.49 | 708 | possibly damaging | 0.707 | 18001 | likely benign | 18 |
569 | TP53 | rs1555526486 | SNP | missense variant | T/I | 123 | 11 | 0.01 | 930 | probably damaging | 0.929 | 24001 | likely benign | 24 |
570 | TP53 | rs587781495 | SNP | missense variant | V/M | 122 | 1 | 0 | 994 | probably damaging | 0.993 | 23001 | likely benign | 23 |
571 | TP53 | rs121912658 | SNP | missense variant | K/E | 120 | 11 | 0.01 | 1000 | probably damaging | 0.999 | 27001 | likely benign | 27 |
572 | TP53 | rs121912658 | SNP | missense variant | K/Q | 120 | 1 | 0 | 1000 | probably damaging | 0.999 | 26001 | likely benign | 26 |
573 | TP53 | rs1555526506 | SNP | missense variant | A/P | 119 | 1 | 0 | 999 | probably damaging | 0.998 | 25001 | likely benign | 25 |
574 | TP53 | rs1064794141 | SNP | missense variant | T/I | 118 | 11 | 0.01 | 1000 | probably damaging | 0.999 | 25001 | likely benign | 25 |
575 | TP53 | rs755238756 | SNP | missense variant | G/A | 117 | 11 | 0.01 | 981 | probably damaging | 0.98 | 24001 | likely benign | 24 |
576 | TP53 | rs755238756 | SNP | missense variant | G/E | 117 | 41 | 0.04 | 999 | probably damaging | 0.998 | 25001 | likely benign | 25 |
577 | TP53 | rs1555526518 | SNP | missense variant | G/R | 117 | 1 | 0 | 1000 | probably damaging | 0.999 | 25001 | likely benign | 25 |
578 | TP53 | rs989692988 | SNP | missense variant | S/A | 116 | 31 | 0.03 | 821 | possibly damaging | 0.82 | 25001 | likely benign | 25 |
579 | TP53 | rs730881996 | SNP | missense variant | H/R | 115 | 31 | 0.03 | 6 | benign | 0.005 | 20001 | likely benign | 20 |
580 | TP53 | rs1555526532 | SNP | missense variant | H/N | 115 | 81 | 0.08 | 8 | benign | 0.007 | 14001 | likely benign | 14 |
581 | TP53 | rs1567555626 | SNP | missense variant | L/F | 114 | 71 | 0.07 | 629 | possibly damaging | 0.628 | 22001 | likely benign | 22 |
582 | TP53 | rs781724995 | SNP | missense variant | L/S | 114 | 531 | 0.53 | 775 | possibly damaging | 0.774 | 24001 | likely benign | 24 |
583 | TP53 | rs1567555667 | SNP | missense variant | F/C | 113 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
584 | TP53 | rs587781642 | SNP | missense variant | F/V | 113 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
585 | TP53 | rs1390502714 | SNP | missense variant | G/A | 112 | 611 | 0.61 | 34 | benign | 0.033 | 17001 | likely benign | 17 |
586 | TP53 | rs1423803759 | SNP | missense variant | G/S | 112 | 801 | 0.8 | 451 | possibly damaging | 0.45 | 21001 | likely benign | 21 |
587 | TP53 | rs1057519997 | SNP | missense variant | L/R | 111 | 1 | 0 | 995 | probably damaging | 0.994 | 25001 | likely benign | 25 |
588 | TP53 | rs1057519997 | SNP | missense variant | L/P | 111 | 1 | 0 | 999 | probably damaging | 0.998 | 26001 | likely benign | 26 |
589 | TP53 | rs1057519997 | SNP | missense variant | L/Q | 111 | 1 | 0 | 997 | probably damaging | 0.996 | 25001 | likely benign | 25 |
590 | TP53 | rs11540654 | SNP | missense variant | R/L | 110 | 51 | 0.05 | 298 | benign | 0.297 | 17001 | likely benign | 17 |
591 | TP53 | rs11540654 | SNP | missense variant | R/P | 110 | 41 | 0.04 | 808 | possibly damaging | 0.807 | 22001 | likely benign | 22 |
592 | TP53 | rs11540654 | SNP | missense variant | R/H | 110 | 171 | 0.17 | 10 | benign | 0.009 | 13001 | likely benign | 13 |
593 | TP53 | rs587781371 | SNP | missense variant | R/C | 110 | 161 | 0.16 | 46 | benign | 0.045 | 21001 | likely benign | 21 |
594 | TP53 | rs587781371 | SNP | missense variant | R/S | 110 | 121 | 0.12 | 405 | benign | 0.404 | 23001 | likely benign | 23 |
595 | TP53 | rs1064796722 | SNP | missense variant | F/C | 109 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
596 | TP53 | rs1064796722 | SNP | missense variant | F/S | 109 | 1 | 0 | 1001 | probably damaging | 1 | 31001 | likely deleterious | 31 |
597 | TP53 | rs1057523496 | SNP | missense variant | F/V | 109 | 1 | 0 | 1001 | probably damaging | 1 | 26001 | likely benign | 26 |
598 | TP53 | rs587782461 | SNP | missense variant | G/C | 108 | 1 | 0 | 494 | possibly damaging | 0.493 | 23001 | likely benign | 23 |
599 | TP53 | rs587782461 | SNP | missense variant | G/R | 108 | 101 | 0.1 | 301 | benign | 0.3 | 20001 | likely benign | 20 |
600 | TP53 | rs587782461 | SNP | missense variant | G/S | 108 | 151 | 0.15 | 326 | benign | 0.325 | 22001 | likely benign | 22 |
601 | TP53 | rs587782447 | SNP | missense variant | Y/C | 107 | 71 | 0.07 | 233 | benign | 0.232 | 22001 | likely benign | 22 |
602 | TP53 | rs587782447 | SNP | missense variant | Y/S | 107 | 41 | 0.04 | 493 | possibly damaging | 0.492 | 24001 | likely benign | 24 |
603 | TP53 | rs368771578 | SNP | missense variant | Y/H | 107 | 711 | 0.71 | 114 | benign | 0.113 | 22001 | likely benign | 22 |
604 | TP53 | rs368771578 | SNP | missense variant | Y/N | 107 | 11 | 0.01 | 926 | probably damaging | 0.925 | 25001 | likely benign | 25 |
605 | TP53 | rs1555526581 | SNP | missense variant | S/R | 106 | 211 | 0.21 | 6 | benign | 0.005 | 6001 | likely benign | 6 |
606 | TP53 | rs1567555883 | SNP | missense variant | S/I | 106 | 71 | 0.07 | 58 | benign | 0.057 | 1001 | likely benign | 1 |
607 | TP53 | rs587781504 | SNP | missense variant | G/V | 105 | 1 | 0 | 998 | probably damaging | 0.997 | 27001 | likely benign | 27 |
608 | TP53 | rs587781504 | SNP | missense variant | G/D | 105 | 1 | 0 | 995 | probably damaging | 0.994 | 24001 | likely benign | 24 |
609 | TP53 | rs1060501195 | SNP | missense variant | G/R | 105 | 1 | 0 | 998 | probably damaging | 0.997 | 24001 | likely benign | 24 |
610 | TP53 | rs1060501195 | SNP | missense variant | G/S | 105 | 51 | 0.05 | 902 | possibly damaging | 0.901 | 23001 | likely benign | 23 |
611 | TP53 | rs1555526589 | SNP | missense variant | Y/H | 103 | 21 | 0.02 | 994 | probably damaging | 0.993 | 26001 | likely benign | 26 |
612 | TP53 | rs786202717 | SNP | missense variant | T/I | 102 | 11 | 0.01 | 45 | benign | 0.044 | 23001 | likely benign | 23 |
613 | TP53 | rs1567555968 | SNP | missense variant | T/S | 102 | 31 | 0.03 | 84 | benign | 0.083 | 17001 | likely benign | 17 |
614 | TP53 | rs878854069 | SNP | missense variant | K/N | 101 | 131 | 0.13 | 38 | benign | 0.037 | 17001 | likely benign | 17 |
615 | TP53 | rs1373046761 | SNP | missense variant | K/E | 101 | 461 | 0.46 | 19 | benign | 0.018 | 19001 | likely benign | 19 |
616 | TP53 | rs1567556019 | SNP | missense variant | S/F | 99 | 1 | 0 | 969 | probably damaging | 0.968 | 25001 | likely benign | 25 |
617 | TP53 | rs1567556019 | SNP | missense variant | S/C | 99 | 11 | 0.01 | 150 | benign | 0.149 | 24001 | likely benign | 24 |
618 | TP53 | rs1245723119 | SNP | missense variant | P/L | 98 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
619 | TP53 | rs730881995 | SNP | missense variant | V/D | 97 | 1 | 0 | 997 | probably damaging | 0.996 | 28001 | likely benign | 28 |
620 | TP53 | rs730882023 | SNP | missense variant | V/F | 97 | 21 | 0.02 | 997 | probably damaging | 0.996 | 25001 | likely benign | 25 |
621 | TP53 | rs730882023 | SNP | missense variant | V/L | 97 | 31 | 0.03 | 800 | possibly damaging | 0.799 | 24001 | likely benign | 24 |
622 | TP53 | rs730882023 | SNP | missense variant | V/I | 97 | 421 | 0.42 | 608 | possibly damaging | 0.607 | 24001 | likely benign | 24 |
623 | TP53 | rs1210700121 | SNP | missense variant | P/L | 92 | 1 | 0 | 336 | benign | 0.335 | 23001 | likely benign | 23 |
624 | TP53 | rs1555526625 | SNP | missense variant | S/F | 90 | 141 | 0.14 | 731 | possibly damaging | 0.73 | 17001 | likely benign | 17 |
625 | TP53 | rs730881994 | SNP | missense variant | P/L | 89 | 161 | 0.16 | 95 | benign | 0.094 | 14001 | likely benign | 14 |
626 | TP53 | rs1555526631 | SNP | missense variant | A/V | 88 | 391 | 0.39 | 31 | benign | 0.03 | 12001 | likely benign | 12 |
627 | TP53 | rs1567556231 | SNP | missense variant | A/P | 88 | 281 | 0.28 | 19 | benign | 0.018 | 12001 | likely benign | 12 |
628 | TP53 | rs587782148 | SNP | missense variant | A/T | 86 | 501 | 0.5 | 12 | benign | 0.011 | 1 | likely benign | 0 |
629 | TP53 | rs587781307 | SNP | missense variant | A/T | 84 | 461 | 0.46 | 13 | benign | 0.012 | 4001 | likely benign | 4 |
630 | TP53 | rs201717599 | SNP | missense variant | A/V | 83 | 251 | 0.25 | 8 | benign | 0.007 | 1 | likely benign | 0 |
631 | TP53 | rs201717599 | SNP | missense variant | A/E | 83 | 721 | 0.72 | 39 | benign | 0.038 | 1 | likely benign | 0 |
632 | TP53 | rs534447939 | SNP | missense variant | P/L | 82 | 101 | 0.1 | 8 | benign | 0.007 | 3001 | likely benign | 3 |
633 | TP53 | rs534447939 | SNP | missense variant | P/R | 82 | 71 | 0.07 | 512 | possibly damaging | 0.511 | 4001 | likely benign | 4 |
634 | TP53 | rs1555526664 | SNP | missense variant | P/A | 82 | 331 | 0.33 | 8 | benign | 0.007 | 4001 | likely benign | 4 |
635 | TP53 | rs1567556386 | SNP | missense variant | T/I | 81 | 261 | 0.26 | 2 | benign | 0.001 | 3001 | likely benign | 3 |
636 | TP53 | rs1060501204 | SNP | missense variant | P/S | 80 | 261 | 0.26 | 51 | benign | 0.05 | 7001 | likely benign | 7 |
637 | TP53 | rs876658527 | SNP | missense variant | A/G | 78 | 241 | 0.24 | 288 | benign | 0.287 | 3001 | likely benign | 3 |
638 | TP53 | rs1555526673 | SNP | missense variant | A/T | 78 | 441 | 0.44 | 21 | benign | 0.02 | 2001 | likely benign | 2 |
639 | TP53 | rs753085009 | SNP | missense variant | P/S | 77 | 491 | 0.49 | 74 | benign | 0.073 | 1 | likely benign | 0 |
640 | TP53 | rs753085009 | SNP | missense variant | P/T | 77 | 211 | 0.21 | 31 | benign | 0.03 | 1 | likely benign | 0 |
641 | TP53 | rs1235781676 | SNP | missense variant | A/E | 76 | 781 | 0.78 | 35 | benign | 0.034 | 1 | likely benign | 0 |
642 | TP53 | rs587781832 | SNP | missense variant | A/V | 74 | 281 | 0.28 | 372 | benign | 0.371 | 1 | likely benign | 0 |
643 | TP53 | rs587782423 | SNP | missense variant | V/M | 73 | 231 | 0.23 | 14 | benign | 0.013 | 1 | likely benign | 0 |
644 | TP53 | rs878854066 | substitution | missense variant | P/R | 72 | 361 | 0.36 | 355 | benign | 0.354 | 5001 | likely benign | 5 |
645 | TP53 | rs730882014 | substitution | missense variant | P/C | 72 | 151 | 0.15 | 616 | possibly damaging | 0.615 | - | ||
646 | TP53 | rs1042522 | SNP | missense variant | P/R | 72 | 361 | 0.36 | 355 | benign | 0.354 | 5001 | likely benign | 5 |
647 | TP53 | rs1042522 | SNP | missense variant | P/H | 72 | 511 | 0.51 | 453 | possibly damaging | 0.452 | 7001 | likely benign | 7 |
648 | TP53 | rs587782769 | SNP | missense variant | P/S | 72 | 701 | 0.7 | 7 | benign | 0.006 | 1 | likely benign | 0 |
649 | TP53 | rs587782769 | SNP | missense variant | P/A | 72 | 661 | 0.66 | 2 | benign | 0.001 | 1 | likely benign | 0 |
650 | TP53 | rs587782769 | SNP | missense variant | P/T | 72 | 421 | 0.42 | 4 | benign | 0.003 | 1 | likely benign | 0 |
651 | TP53 | rs878854065 | SNP | missense variant | P/R | 71 | 151 | 0.15 | 112 | benign | 0.111 | 4001 | likely benign | 4 |
652 | TP53 | rs1567556576 | SNP | missense variant | P/S | 71 | 621 | 0.62 | 13 | benign | 0.012 | 1 | likely benign | 0 |
653 | TP53 | rs1567556576 | SNP | missense variant | P/A | 71 | 701 | 0.7 | 2 | benign | 0.001 | 1 | likely benign | 0 |
654 | TP53 | rs1567556594 | SNP | missense variant | A/V | 70 | 251 | 0.25 | 97 | benign | 0.096 | 9001 | likely benign | 9 |
655 | TP53 | rs756233241 | SNP | missense variant | A/V | 69 | 391 | 0.39 | 30 | benign | 0.029 | 7001 | likely benign | 7 |
656 | TP53 | rs756233241 | SNP | missense variant | A/G | 69 | 441 | 0.44 | 21 | benign | 0.02 | 4001 | likely benign | 4 |
657 | TP53 | rs1567556618 | SNP | missense variant | A/T | 69 | 601 | 0.6 | 21 | benign | 0.02 | 1 | likely benign | 0 |
658 | TP53 | rs869312782 | SNP | missense variant | E/Q | 68 | 451 | 0.45 | 42 | benign | 0.041 | 3001 | likely benign | 3 |
659 | TP53 | rs1555526709 | SNP | missense variant | P/Q | 67 | 241 | 0.24 | 15 | benign | 0.014 | 3001 | likely benign | 3 |
660 | TP53 | rs1555526711 | SNP | missense variant | M/I | 66 | 201 | 0.2 | 4 | benign | 0.003 | 1 | likely benign | 0 |
661 | TP53 | rs1060501210 | SNP | missense variant | R/T | 65 | 581 | 0.58 | 4 | benign | 0.003 | 1 | likely benign | 0 |
662 | TP53 | rs372201428 | SNP | missense variant | A/V | 63 | 241 | 0.24 | 13 | benign | 0.012 | 4001 | likely benign | 4 |
663 | TP53 | rs372201428 | SNP | missense variant | A/G | 63 | 191 | 0.19 | 13 | benign | 0.012 | 6001 | likely benign | 6 |
664 | TP53 | rs876658902 | SNP | missense variant | A/T | 63 | 271 | 0.27 | 8 | benign | 0.007 | 3001 | likely benign | 3 |
665 | TP53 | rs1460793472 | SNP | missense variant | D/G | 61 | 141 | 0.14 | 13 | benign | 0.012 | 15001 | likely benign | 15 |
666 | TP53 | rs1237722021 | SNP | missense variant | G/C | 59 | 81 | 0.08 | 167 | benign | 0.166 | 6001 | likely benign | 6 |
667 | TP53 | rs144386518 | SNP | missense variant | P/R | 58 | 481 | 0.48 | 905 | possibly damaging | 0.904 | 1001 | likely benign | 1 |
668 | TP53 | rs587782776 | SNP | missense variant | D/E | 57 | 541 | 0.54 | 6 | benign | 0.005 | 1 | likely benign | 0 |
669 | TP53 | rs1442824382 | SNP | missense variant | D/G | 57 | 271 | 0.27 | 2 | benign | 0.001 | 1 | likely benign | 0 |
670 | TP53 | rs1555526742 | SNP | missense variant | F/L | 54 | 1001 | 1 | 1 | benign | 0 | 1 | likely benign | 0 |
671 | TP53 | rs774656101 | SNP | missense variant | Q/R | 52 | 431 | 0.43 | 8 | benign | 0.007 | 2001 | likely benign | 2 |
672 | TP53 | rs1567556923 | SNP | missense variant | E/G | 51 | 261 | 0.26 | 63 | benign | 0.062 | 1 | likely benign | 0 |
673 | TP53 | rs370502517 | SNP | missense variant | I/T | 50 | 451 | 0.45 | 8 | benign | 0.007 | 5001 | likely benign | 5 |
674 | TP53 | rs370502517 | SNP | missense variant | I/N | 50 | 251 | 0.25 | 99 | benign | 0.098 | 9001 | likely benign | 9 |
675 | TP53 | rs759728549 | SNP | missense variant | D/G | 49 | 161 | 0.16 | 42 | benign | 0.041 | 6001 | likely benign | 6 |
676 | TP53 | rs587780728 | SNP | missense variant | D/H | 49 | 31 | 0.03 | 914 | probably damaging | 0.913 | 16001 | likely benign | 16 |
677 | TP53 | rs587780728 | SNP | missense variant | D/N | 49 | 201 | 0.2 | 63 | benign | 0.062 | 5001 | likely benign | 5 |
678 | TP53 | rs587781460 | SNP | missense variant | D/E | 48 | 1001 | 1 | 4 | benign | 0.003 | 1 | likely benign | 0 |
679 | TP53 | rs1800371 | SNP | missense variant | P/S | 47 | 201 | 0.2 | 21 | benign | 0.02 | 1 | likely benign | 0 |
680 | TP53 | rs1800371 | SNP | missense variant | P/T | 47 | 201 | 0.2 | 13 | benign | 0.012 | 1 | likely benign | 0 |
681 | TP53 | rs876659630 | SNP | missense variant | S/P | 46 | 241 | 0.24 | 2 | benign | 0.001 | 5001 | likely benign | 5 |
682 | TP53 | rs879254066 | SNP | missense variant | L/P | 45 | 21 | 0.02 | 21 | benign | 0.02 | 15001 | likely benign | 15 |
683 | TP53 | rs1060501190 | SNP | missense variant | M/I | 44 | 241 | 0.24 | 6 | benign | 0.005 | 1 | likely benign | 0 |
684 | TP53 | rs754332870 | SNP | missense variant | L/F | 43 | 161 | 0.16 | 223 | benign | 0.222 | 12001 | likely benign | 12 |
685 | TP53 | rs587781767 | SNP | missense variant | D/G | 42 | 111 | 0.11 | 30 | benign | 0.029 | 14001 | likely benign | 14 |
686 | TP53 | rs756847009 | SNP | missense variant | D/N | 42 | 191 | 0.19 | 21 | benign | 0.02 | 10001 | likely benign | 10 |
687 | TP53 | rs1555526789 | SNP | missense variant | D/N | 41 | 261 | 0.26 | 21 | benign | 0.02 | 9001 | likely benign | 9 |
688 | TP53 | rs587782877 | SNP | missense variant | M/T | 40 | 361 | 0.36 | 63 | benign | 0.062 | 4001 | likely benign | 4 |
689 | TP53 | rs1353016807 | SNP | missense variant | A/V | 39 | 151 | 0.15 | 140 | benign | 0.139 | 5001 | likely benign | 5 |
690 | TP53 | rs1567557177 | SNP | missense variant | S/F | 37 | 11 | 0.01 | 558 | possibly damaging | 0.557 | 15001 | likely benign | 15 |
691 | TP53 | rs587781866 | SNP | missense variant | P/L | 36 | 401 | 0.4 | 1 | benign | 0 | 1001 | likely benign | 1 |
692 | TP53 | rs587781866 | SNP | missense variant | P/Q | 36 | 591 | 0.59 | 193 | benign | 0.192 | 1 | likely benign | 0 |
693 | TP53 | rs730881993 | SNP | missense variant | P/S | 36 | 761 | 0.76 | 27 | benign | 0.026 | 1 | likely benign | 0 |
694 | TP53 | rs121912661 | SNP | missense variant | L/F | 35 | 731 | 0.73 | 214 | benign | 0.213 | 1 | likely benign | 0 |
695 | TP53 | rs121912661 | SNP | missense variant | L/F | 35 | 731 | 0.73 | 214 | benign | 0.213 | 1 | likely benign | 0 |
696 | TP53 | rs1060501211 | SNP | missense variant | L/M | 35 | 231 | 0.23 | 310 | benign | 0.309 | 5001 | likely benign | 5 |
697 | TP53 | rs1322947350 | SNP | missense variant | P/R | 34 | 91 | 0.09 | 92 | benign | 0.091 | 7001 | likely benign | 7 |
698 | TP53 | rs786201968 | SNP | missense variant | P/A | 34 | 201 | 0.2 | 4 | benign | 0.003 | 1 | likely benign | 0 |
699 | TP53 | rs786201968 | SNP | missense variant | P/T | 34 | 251 | 0.25 | 1 | benign | 0 | 1 | likely benign | 0 |
700 | TP53 | rs1555526832 | SNP | missense variant | S/Y | 33 | 231 | 0.23 | 30 | benign | 0.029 | 10001 | likely benign | 10 |
701 | TP53 | rs201753350 | SNP | missense variant | V/F | 31 | 161 | 0.16 | 23 | benign | 0.022 | 12001 | likely benign | 12 |
702 | TP53 | rs201753350 | SNP | missense variant | V/I | 31 | 261 | 0.26 | 6 | benign | 0.005 | 8001 | likely benign | 8 |
703 | TP53 | rs1011445550 | SNP | missense variant | N/K | 29 | 771 | 0.77 | 2 | benign | 0.001 | 8001 | likely benign | 8 |
704 | TP53 | rs786202289 | SNP | missense variant | E/V | 28 | 201 | 0.2 | 288 | benign | 0.287 | 22001 | likely benign | 22 |
705 | TP53 | rs1555526933 | SNP | missense variant | P/L | 27 | 81 | 0.08 | 161 | benign | 0.16 | 23001 | likely benign | 23 |
706 | TP53 | rs922736614 | SNP | missense variant | P/S | 27 | 111 | 0.11 | 273 | benign | 0.272 | 23001 | likely benign | 23 |
707 | TP53 | rs922736614 | SNP | missense variant | P/T | 27 | 151 | 0.15 | 250 | benign | 0.249 | 25001 | likely benign | 25 |
708 | TP53 | rs1800369 | SNP | missense variant | D/E | 21 | 531 | 0.53 | 18 | benign | 0.017 | 13001 | likely benign | 13 |
709 | TP53 | rs876659913 | SNP | missense variant | S/P | 20 | 111 | 0.11 | 133 | benign | 0.132 | 22001 | likely benign | 22 |
710 | TP53 | rs1567558112 | SNP | missense variant | L/V | 14 | 51 | 0.05 | 768 | possibly damaging | 0.767 | 23001 | likely benign | 23 |
711 | TP53 | rs878854070 | SNP | missense variant | P/L | 13 | 1 | 0 | 623 | possibly damaging | 0.622 | 25001 | likely benign | 25 |
712 | TP53 | rs878854070 | SNP | missense variant | P/R | 13 | 1 | 0 | 989 | probably damaging | 0.988 | 24001 | likely benign | 24 |
713 | TP53 | rs1060501208 | SNP | missense variant | P/S | 13 | 51 | 0.05 | 741 | possibly damaging | 0.74 | 23001 | likely benign | 23 |
714 | TP53 | rs1482497533 | SNP | missense variant | P/L | 12 | 521 | 0.52 | 25 | benign | 0.024 | 11001 | likely benign | 11 |
715 | TP53 | rs1482497533 | SNP | missense variant | P/R | 12 | 191 | 0.19 | 852 | possibly damaging | 0.851 | 18001 | likely benign | 18 |
716 | TP53 | rs1482497533 | SNP | missense variant | P/H | 12 | 71 | 0.07 | 941 | probably damaging | 0.94 | 22001 | likely benign | 22 |
717 | TP53 | rs201382018 | SNP | missense variant | E/Q | 11 | 41 | 0.04 | 952 | probably damaging | 0.951 | 23001 | likely benign | 23 |
718 | TP53 | rs201382018 | SNP | missense variant | E/K | 11 | 11 | 0.01 | 892 | possibly damaging | 0.891 | 23001 | likely benign | 23 |
719 | TP53 | rs1418778734 | SNP | missense variant | V/G | 10 | 71 | 0.07 | 188 | benign | 0.187 | 13001 | likely benign | 13 |
720 | TP53 | rs535274413 | SNP | missense variant | V/L | 10 | 1001 | 1 | 4 | benign | 0.003 | 1 | likely benign | 0 |
721 | TP53 | rs535274413 | SNP | missense variant | V/I | 10 | 551 | 0.55 | 2 | benign | 0.001 | 1 | likely benign | 0 |
722 | TP53 | rs757282628 | SNP | missense variant | S/R | 9 | 231 | 0.23 | 711 | possibly damaging | 0.71 | 9001 | likely benign | 9 |
723 | TP53 | rs1555527015 | SNP | missense variant | S/N | 9 | 251 | 0.25 | 13 | benign | 0.012 | 1 | likely benign | 0 |
724 | TP53 | rs1555527017 | SNP | missense variant | S/R | 9 | 231 | 0.23 | 711 | possibly damaging | 0.71 | 9001 | likely benign | 9 |
725 | TP53 | rs876659415 | SNP | missense variant | P/L | 8 | 421 | 0.42 | 1 | benign | 0 | 4001 | likely benign | 4 |
726 | TP53 | rs587781277 | SNP | missense variant | D/E | 7 | 381 | 0.38 | 95 | benign | 0.094 | 1 | likely benign | 0 |
727 | TP53 | rs587781277 | SNP | missense variant | D/E | 7 | 381 | 0.38 | 95 | benign | 0.094 | 1 | likely benign | 0 |
728 | TP53 | rs587782646 | SNP | missense variant | D/H | 7 | 1 | 0 | 979 | probably damaging | 0.978 | 23001 | likely benign | 23 |
729 | TP53 | rs1357147493 | SNP | missense variant | S/P | 6 | 61 | 0.06 | 852 | possibly damaging | 0.851 | 15001 | likely benign | 15 |
730 | TP53 | rs781595324 | SNP | missense variant | Q/R | 5 | 161 | 0.16 | 140 | benign | 0.139 | 7001 | likely benign | 7 |
731 | TP53 | rs878854064 | SNP | missense variant | P/L | 4 | 41 | 0.04 | 32 | benign | 0.031 | 9001 | likely benign | 9 |
732 | TP53 | rs878854064 | SNP | missense variant | P/R | 4 | 11 | 0.01 | 799 | possibly damaging | 0.798 | 14001 | likely benign | 14 |
733 | TP53 | rs1356004172 | SNP | missense variant | P/T | 4 | 51 | 0.05 | 45 | benign | 0.044 | 1 | likely benign | 0 |
734 | TP53 | rs786203938 | SNP | missense variant | E/G | 3 | 1 | 0 | 778 | possibly damaging | 0.777 | 24001 | likely benign | 24 |
735 | TP53 | rs769884991 | SNP | missense variant | E/K | 2 | 11 | 0.01 | 842 | possibly damaging | 0.841 | 23001 | likely benign | 23 |
736 | PIK3CA | rs751557352 | SNP | missense variant | S/T | 2 | 11 | 0.01 | 842 | possibly damaging | 0.841 | 20001 | likely benign | 20 |
737 | PIK3CA | rs1220116506 | SNP | missense variant | R/Q | 3 | 21 | 0.02 | 975 | probably damaging | 0.974 | 23001 | likely benign | 23 |
738 | PIK3CA | rs1260684206 | SNP | missense variant | E/G | 4 | 1 | 0 | 1001 | probably damaging | 1 | 24001 | likely benign | 24 |
739 | PIK3CA | rs1436163100 | SNP | missense variant | G/E | 6 | 1 | 0 | 1001 | probably damaging | 1 | 22001 | likely benign | 22 |
740 | PIK3CA | rs369950390 | SNP | missense variant | Y/C | 9 | 171 | 0.17 | 86 | benign | 0.085 | 23001 | likely benign | 23 |
741 | PIK3CA | rs199747934 | SNP | missense variant | H/N | 11 | 221 | 0.22 | 8 | benign | 0.007 | 20001 | likely benign | 20 |
742 | PIK3CA | rs201631515 | SNP | missense variant | A/T | 12 | 951 | 0.95 | 4 | benign | 0.003 | 20001 | likely benign | 20 |
743 | PIK3CA | rs201631515 | SNP | missense variant | A/S | 12 | 791 | 0.79 | 4 | benign | 0.003 | 18001 | likely benign | 18 |
744 | PIK3CA | rs200031978 | SNP | missense variant | G/V | 13 | 101 | 0.1 | 418 | benign | 0.417 | 21001 | likely benign | 21 |
745 | PIK3CA | rs201371389 | SNP | missense variant | N/S | 16 | 481 | 0.48 | 10 | benign | 0.009 | 19001 | likely benign | 19 |
746 | PIK3CA | rs1423200481 | SNP | missense variant | L/F | 24 | 11 | 0.01 | 860 | possibly damaging | 0.859 | 20001 | likely benign | 20 |
747 | PIK3CA | rs104885999 | SNP | missense variant | R/K | 25 | 141 | 0.14 | 139 | benign | 0.138 | 19001 | likely benign | 19 |
748 | PIK3CA | rs1302938521 | SNP | missense variant | D/G | 28 | 11 | 0.01 | 991 | probably damaging | 0.99 | 27001 | likely benign | 27 |
749 | PIK3CA | rs59971989 | SNP | missense variant | K/E | 29 | 911 | 0.91 | 186 | benign | 0.185 | 19001 | likely benign | 19 |
750 | PIK3CA | rs1387024511 | SNP | missense variant | K/Q | 33 | 21 | 0.02 | 140 | benign | 0.139 | 16001 | likely benign | 16 |
751 | PIK3CA | rs1266238180 | SNP | missense variant | K/R | 33 | 1001 | 1 | 1 | benign | 0 | 16001 | likely benign | 16 |
752 | PIK3CA | rs1560144842 | SNP | missense variant | A/T | 34 | 241 | 0.24 | 87 | benign | 0.086 | 21001 | likely benign | 21 |
753 | PIK3CA | rs1466575763 | SNP | missense variant | I/V | 35 | 341 | 0.34 | 7 | benign | 0.006 | 17001 | likely benign | 17 |
754 | PIK3CA | rs121913285 | SNP | missense variant | P/R | 40 | 1 | 0 | 996 | probably damaging | 0.995 | 26001 | likely benign | 26 |
755 | PIK3CA | rs121913273 | SNP | missense variant | E/K | 43 | 1 | 0 | 1000 | probably damaging | 0.999 | 32001 | likely deleterious | 32 |
756 | PIK3CA | rs121913273 | SNP | missense variant | E/Q | 43 | 1 | 0 | 1000 | probably damaging | 0.999 | 25001 | likely benign | 25 |
757 | PIK3CA | rs1057519927 | SNP | missense variant | E/A | 43 | 1 | 0 | 1000 | probably damaging | 0.999 | 27001 | likely benign | 27 |
758 | PIK3CA | rs1057519927 | SNP | missense variant | E/G | 43 | 1 | 0 | 1001 | probably damaging | 1 | 23001 | likely benign | 23 |
759 | PIK3CA | rs1057519927 | SNP | missense variant | E/V | 43 | 1 | 0 | 1001 | probably damaging | 1 | 31001 | likely deleterious | 31 |
760 | PIK3CA | rs104886003 | SNP | missense variant | E/K | 46 | 1 | 0 | 1000 | probably damaging | 0.999 | 31001 | likely deleterious | 31 |
761 | PIK3CA | rs104886003 | SNP | missense variant | E/Q | 46 | 1 | 0 | 1000 | probably damaging | 0.999 | 24001 | likely benign | 24 |
762 | PIK3CA | rs121913274 | SNP | missense variant | E/A | 46 | 1 | 0 | 1000 | probably damaging | 0.999 | 27001 | likely benign | 27 |
763 | PIK3CA | rs121913274 | SNP | missense variant | E/G | 46 | 1 | 0 | 1001 | probably damaging | 1 | 31001 | likely deleterious | 31 |
764 | PIK3CA | rs121913274 | SNP | missense variant | E/V | 46 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
765 | PIK3CA | rs121913275 | SNP | missense variant | E/D | 46 | 1 | 0 | 1000 | probably damaging | 0.999 | 23001 | likely benign | 23 |
766 | PIK3CA | rs121913275 | SNP | missense variant | E/D | 46 | 1 | 0 | 1000 | probably damaging | 0.999 | 23001 | likely benign | 23 |
767 | PIK3CA | rs121913286 | SNP | missense variant | Q/K | 47 | 1 | 0 | 1000 | probably damaging | 0.999 | 25001 | likely benign | 25 |
768 | PIK3CA | rs121913286 | SNP | missense variant | Q/E | 47 | 1 | 0 | 1000 | probably damaging | 0.999 | 21001 | likely benign | 21 |
769 | PIK3CA | rs397517201 | SNP | missense variant | Q/P | 47 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
770 | PIK3CA | rs397517201 | SNP | missense variant | Q/R | 47 | 1 | 0 | 1000 | probably damaging | 0.999 | 26001 | likely benign | 26 |
771 | PIK3CA | rs397517201 | SNP | missense variant | Q/L | 47 | 1 | 0 | 1000 | probably damaging | 0.999 | 25001 | likely benign | 25 |
772 | PIK3CA | rs1057519940 | SNP | missense variant | Q/H | 47 | 1 | 0 | 1001 | probably damaging | 1 | 21001 | likely benign | 21 |
773 | PIK3CA | rs1057519699 | SNP | missense variant | D/N | 50 | 11 | 0.01 | 976 | probably damaging | 0.975 | 25001 | likely benign | 25 |
774 | PIK3CA | rs988134846 | SNP | missense variant | L/V | 52 | 1 | 0 | 768 | possibly damaging | 0.767 | 22001 | likely benign | 22 |
775 | PIK3CA | rs104886000 | SNP | missense variant | R/K | 56 | 1 | 0 | 1000 | probably damaging | 0.999 | 33001 | likely deleterious | 33 |
776 | PIK3CA | rs1302992156 | SNP | missense variant | C/Y | 57 | 1 | 0 | 990 | probably damaging | 0.989 | 22001 | likely benign | 22 |
777 | PIK3CA | rs1425149965 | SNP | missense variant | I/T | 58 | 1 | 0 | 951 | probably damaging | 0.95 | 5001 | likely benign | 5 |
778 | MYC | rs778595707 | SNP | missense variant | D/Y | 2 | 1 | 0 | 655 | possibly damaging | 0.654 | 31001 | likely deleterious | 31 |
779 | MYC | rs772459508 | SNP | missense variant | F/L | 3 | 1 | 0 | 1 | benign | 0 | 18001 | likely benign | 18 |
780 | MYC | rs747141352 | SNP | missense variant | R/Q | 5 | 1 | 0 | 1 | benign | 0 | 22001 | likely benign | 22 |
781 | MYC | rs747141352 | SNP | missense variant | R/P | 5 | 1 | 0 | 152 | benign | 0.151 | 20001 | likely benign | 20 |
782 | MYC | rs777141161 | SNP | missense variant | V/I | 6 | 531 | 0.53 | 1 | benign | 0 | 2001 | likely benign | 2 |
783 | MYC | rs759986640 | SNP | missense variant | E/G | 8 | 511 | 0.51 | 1 | benign | 0 | 22001 | likely benign | 22 |
784 | MYC | rs1381903406 | SNP | missense variant | N/I | 9 | 211 | 0.21 | 1 | benign | 0 | 12001 | likely benign | 12 |
785 | MYC | rs1319018025 | SNP | missense variant~splice region variant | Q/H | 10 | 131 | 0.13 | 56 | benign | 0.055 | 28001 | likely benign | 28 |
786 | MYC | rs139294902 | SNP | missense variant | P/R | 12 | 61 | 0.06 | 28 | benign | 0.027 | 21001 | likely benign | 21 |
787 | MYC | rs770253839 | SNP | missense variant | A/T | 14 | 511 | 0.51 | 1 | benign | 0 | 14001 | likely benign | 14 |
788 | MYC | rs775909833 | SNP | missense variant | T/K | 15 | 31 | 0.03 | 2 | benign | 0.001 | 23001 | likely benign | 23 |
789 | MYC | rs1382266165 | SNP | missense variant | P/S | 17 | 31 | 0.03 | 958 | probably damaging | 0.957 | 27001 | likely benign | 27 |
790 | MYC | rs149992096 | SNP | missense variant | N/K | 19 | 141 | 0.14 | 191 | benign | 0.19 | 23001 | likely benign | 23 |
791 | MYC | rs146505192 | SNP | missense variant | F/L | 22 | 1001 | 1 | 8 | benign | 0.007 | 15001 | likely benign | 15 |
792 | MYC | rs146505192 | SNP | missense variant | F/V | 22 | 111 | 0.11 | 131 | benign | 0.13 | 22001 | likely benign | 22 |
793 | MYC | rs1490644442 | SNP | missense variant | N/Y | 24 | 291 | 0.29 | 801 | possibly damaging | 0.8 | 24001 | likely benign | 24 |
794 | MYC | rs148915481 | SNP | missense variant | N/S | 24 | 1001 | 1 | 8 | benign | 0.007 | 11001 | likely benign | 11 |
795 | MYC | rs4645959 | SNP | missense variant | N/T | 26 | 31 | 0.03 | 16 | benign | 0.015 | 28001 | likely benign | 28 |
796 | MYC | rs4645959 | SNP | missense variant | N/S | 26 | 11 | 0.01 | 161 | benign | 0.16 | 26001 | likely benign | 26 |
797 | MYC | rs1418866533 | SNP | missense variant | Y/N | 27 | 111 | 0.11 | 949 | probably damaging | 0.948 | 25001 | likely benign | 25 |
798 | MYC | rs1183060749 | SNP | missense variant | D/V | 28 | 1 | 0 | 1000 | probably damaging | 0.999 | 32001 | likely deleterious | 32 |
799 | MYC | rs375812644 | SNP | missense variant | L/V | 29 | 41 | 0.04 | 364 | benign | 0.363 | 25001 | likely benign | 25 |
800 | MYC | rs764006760 | SNP | missense variant | Y/C | 31 | 1 | 0 | 995 | probably damaging | 0.994 | 31001 | likely deleterious | 31 |
801 | MYC | rs776780683 | SNP | missense variant | S/L | 33 | 31 | 0.03 | 991 | probably damaging | 0.99 | 28001 | likely benign | 28 |
802 | MYC | rs781313941 | SNP | missense variant | V/M | 34 | 141 | 0.14 | 296 | benign | 0.295 | 21001 | likely benign | 21 |
803 | MYC | rs1395774855 | SNP | missense variant | D/G | 41 | 1 | 0 | 486 | possibly damaging | 0.485 | 32001 | likely deleterious | 32 |
804 | MYC | rs1563757581 | SNP | missense variant | D/E | 41 | 101 | 0.1 | 13 | benign | 0.012 | 22001 | likely benign | 22 |
805 | MYC | rs1391743516 | SNP | missense variant | E/D | 43 | 721 | 0.72 | 916 | probably damaging | 0.915 | 11001 | likely benign | 11 |
806 | MYC | rs745993896 | SNP | missense variant | E/D | 44 | 861 | 0.86 | 237 | benign | 0.236 | 23001 | likely benign | 23 |
807 | MYC | rs780361249 | SNP | missense variant | F/S | 46 | 41 | 0.04 | 644 | possibly damaging | 0.643 | 32001 | likely deleterious | 32 |
808 | MYC | rs114570780 | SNP | missense variant | Y/H | 47 | 1 | 0 | 956 | probably damaging | 0.955 | 31001 | likely deleterious | 31 |
809 | MYC | rs61752959 | SNP | missense variant | Q/H | 48 | 541 | 0.54 | 1 | benign | 0 | 15001 | likely benign | 15 |
810 | MYC | rs949318807 | SNP | missense variant | Q/R | 49 | 651 | 0.65 | 331 | benign | 0.33 | 22001 | likely benign | 22 |
811 | MYC | rs900683143 | SNP | missense variant | Q/H | 50 | 261 | 0.26 | 42 | benign | 0.041 | 22001 | likely benign | 22 |
812 | MYC | rs1270296696 | SNP | missense variant | Q/K | 52 | 611 | 0.61 | 75 | benign | 0.074 | 21001 | likely benign | 21 |
813 | MYC | rs1329377103 | SNP | missense variant | Q/L | 52 | 191 | 0.19 | 99 | benign | 0.098 | 23001 | likely benign | 23 |
814 | MYC | rs1250123425 | SNP | missense variant | S/R | 53 | 11 | 0.01 | 877 | possibly damaging | 0.876 | 27001 | likely benign | 27 |
815 | MYC | rs770534113 | SNP | missense variant | E/K | 54 | 501 | 0.5 | 385 | benign | 0.384 | 25001 | likely benign | 25 |
816 | MYC | rs770534113 | SNP | missense variant | E/Q | 54 | 641 | 0.64 | 158 | benign | 0.157 | 24001 | likely benign | 24 |
817 | MYC | rs121918684 | SNP | missense variant | E/D | 54 | 361 | 0.36 | 32 | benign | 0.031 | 23001 | likely benign | 23 |
818 | MYC | rs1240451313 | SNP | missense variant | L/P | 55 | 51 | 0.05 | 183 | benign | 0.182 | 26001 | likely benign | 26 |
819 | MYC | rs1240451313 | SNP | missense variant | L/R | 55 | 1 | 0 | 957 | probably damaging | 0.956 | 29001 | likely benign | 29 |
820 | MYC | rs1057519849 | SNP | missense variant | P/S | 57 | 1 | 0 | 623 | possibly damaging | 0.622 | 26001 | likely benign | 26 |
821 | MYC | rs1037072564 | SNP | missense variant | P/L | 57 | 1 | 0 | 983 | probably damaging | 0.982 | 29001 | likely benign | 29 |
822 | MYC | rs1057519918 | SNP | missense variant | P/L | 58 | 1 | 0 | 1000 | probably damaging | 0.999 | 29001 | likely benign | 29 |
823 | MYC | rs775522201 | SNP | missense variant | A/V | 59 | 31 | 0.03 | 997 | probably damaging | 0.996 | 29001 | likely benign | 29 |
824 | MYC | rs1437767389 | SNP | missense variant | E/D | 62 | 1 | 0 | 992 | probably damaging | 0.991 | 26001 | likely benign | 26 |
825 | MYC | rs751452834 | SNP | missense variant | D/A | 63 | 1 | 0 | 999 | probably damaging | 0.998 | 32001 | likely deleterious | 32 |
826 | MYC | rs1403660912 | SNP | missense variant | L/M | 70 | 1 | 0 | 1000 | probably damaging | 0.999 | 25001 | likely benign | 25 |
827 | MYC | rs28933407 | SNP | missense variant | P/S | 72 | 31 | 0.03 | 623 | possibly damaging | 0.622 | 28001 | likely benign | 28 |
828 | MYC | rs750664148 | SNP | missense variant | T/P | 73 | 31 | 0.03 | 969 | probably damaging | 0.968 | 25001 | likely benign | 25 |
829 | MYC | rs750664148 | SNP | missense variant | T/A | 73 | 21 | 0.02 | 344 | benign | 0.343 | 24001 | likely benign | 24 |
830 | MYC | rs756091827 | SNP | missense variant | T/S | 73 | 11 | 0.01 | 807 | possibly damaging | 0.806 | 24001 | likely benign | 24 |
831 | MYC | rs756091827 | SNP | missense variant | T/I | 73 | 1 | 0 | 899 | possibly damaging | 0.898 | 28001 | likely benign | 28 |
832 | MYC | rs121918685 | SNP | missense variant | P/A | 74 | 11 | 0.01 | 999 | probably damaging | 0.998 | 27001 | likely benign | 27 |
833 | MYC | rs1294281543 | SNP | missense variant | P/L | 74 | 1 | 0 | 1000 | probably damaging | 0.999 | 31001 | likely deleterious | 31 |
834 | MYC | rs780202654 | SNP | missense variant | L/R | 76 | 1 | 0 | 989 | probably damaging | 0.988 | 24001 | likely benign | 24 |
835 | MYC | rs1563757684 | SNP | missense variant | S/T | 77 | 1 | 0 | 987 | probably damaging | 0.986 | 25001 | likely benign | 25 |
836 | MYC | rs1057519850 | SNP | missense variant | S/F | 77 | 1 | 0 | 998 | probably damaging | 0.997 | 31001 | likely deleterious | 31 |
837 | MYC | rs931443247 | SNP | missense variant | S/C | 79 | 1 | 0 | 990 | probably damaging | 0.989 | 29001 | likely benign | 29 |
838 | MYC | rs1460265619 | SNP | missense variant | R/C | 80 | 21 | 0.02 | 336 | benign | 0.335 | 32001 | likely deleterious | 32 |
839 | MYC | rs375402667 | SNP | missense variant | R/S | 81 | 71 | 0.07 | 961 | probably damaging | 0.96 | 24001 | likely benign | 24 |
840 | MYC | rs375402667 | SNP | missense variant | R/G | 81 | 121 | 0.12 | 961 | probably damaging | 0.96 | 25001 | likely benign | 25 |
841 | MYC | rs375402667 | SNP | missense variant | R/C | 81 | 11 | 0.01 | 994 | probably damaging | 0.993 | 31001 | likely deleterious | 31 |
842 | MYC | rs1420068922 | SNP | missense variant | R/H | 81 | 11 | 0.01 | 485 | possibly damaging | 0.484 | 30001 | likely deleterious | 30 |
843 | MYC | rs1484385745 | SNP | missense variant | L/V | 84 | 181 | 0.18 | 970 | probably damaging | 0.969 | 21001 | likely benign | 21 |
844 | MYC | rs1184821004 | SNP | missense variant | C/S | 85 | 441 | 0.44 | 1 | benign | 0 | 22001 | likely benign | 22 |
845 | MYC | rs1184821004 | SNP | missense variant | C/R | 85 | 361 | 0.36 | 70 | benign | 0.069 | 23001 | likely benign | 23 |
846 | MYC | rs776077629 | SNP | missense variant | C/F | 85 | 701 | 0.7 | 44 | benign | 0.043 | 23001 | likely benign | 23 |
847 | MYC | rs745545434 | SNP | missense variant | C/W | 85 | 191 | 0.19 | 1 | benign | 0 | 25001 | likely benign | 25 |
848 | MYC | rs886556187 | SNP | missense variant | S/L | 86 | 191 | 0.19 | 948 | probably damaging | 0.947 | 24001 | likely benign | 24 |
849 | MYC | rs1371389460 | SNP | missense variant | S/C | 88 | 21 | 0.02 | 622 | possibly damaging | 0.621 | 26001 | likely benign | 26 |
850 | MYC | rs866188449 | SNP | missense variant | V/I | 90 | 421 | 0.42 | 4 | benign | 0.003 | 14001 | likely benign | 14 |
851 | MYC | rs866188449 | SNP | missense variant | V/L | 90 | 671 | 0.67 | 4 | benign | 0.003 | 14001 | likely benign | 14 |
852 | MYC | rs148228388 | SNP | missense variant | A/E | 91 | 71 | 0.07 | 453 | possibly damaging | 0.452 | 17001 | likely benign | 17 |
853 | MYC | rs1563757725 | SNP | missense variant | T/R | 93 | 361 | 0.36 | 1 | benign | 0 | 18001 | likely benign | 18 |
854 | MYC | rs764188937 | SNP | missense variant | R/P | 98 | 331 | 0.33 | 1 | benign | 0 | 23001 | likely benign | 23 |
855 | MYC | rs764188937 | SNP | missense variant | R/L | 98 | 521 | 0.52 | 134 | benign | 0.133 | 20001 | likely benign | 20 |
856 | MYC | rs1362063441 | SNP | missense variant | G/E | 99 | 271 | 0.27 | 4 | benign | 0.003 | 18001 | likely benign | 18 |
857 | MYC | rs1362063441 | SNP | missense variant | G/A | 99 | 211 | 0.21 | 6 | benign | 0.005 | 17001 | likely benign | 17 |
858 | MYC | rs979999500 | SNP | missense variant | D/G | 100 | 551 | 0.55 | 4 | benign | 0.003 | 19001 | likely benign | 19 |
859 | MYC | rs1383206618 | SNP | missense variant | N/H | 101 | 591 | 0.59 | 177 | benign | 0.176 | 19001 | likely benign | 19 |
860 | MYC | rs121918683 | SNP | missense variant | N/T | 101 | 431 | 0.43 | 22 | benign | 0.021 | 18001 | likely benign | 18 |
861 | MYC | rs767360326 | SNP | missense variant | N/K | 101 | 371 | 0.37 | 28 | benign | 0.027 | 14001 | likely benign | 14 |
862 | MYC | rs750561207 | SNP | missense variant | D/G | 102 | 411 | 0.41 | 1 | benign | 0 | 15001 | likely benign | 15 |
863 | MYC | rs868656085 | SNP | missense variant | D/E | 102 | 1001 | 1 | 149 | benign | 0.148 | 13001 | likely benign | 13 |
864 | MYC | rs1034655525 | SNP | missense variant | G/D | 103 | 121 | 0.12 | 849 | possibly damaging | 0.848 | 24001 | likely benign | 24 |
865 | MYC | rs199561469 | SNP | missense variant | G/S | 104 | 641 | 0.64 | 678 | possibly damaging | 0.677 | 24001 | likely benign | 24 |
866 | MYC | rs199561469 | SNP | missense variant | G/R | 104 | 231 | 0.23 | 916 | probably damaging | 0.915 | 25001 | likely benign | 25 |
867 | MYC | rs1314120778 | SNP | missense variant | S/F | 109 | 21 | 0.02 | 543 | possibly damaging | 0.542 | 27001 | likely benign | 27 |
868 | MYC | rs1296200537 | SNP | missense variant | D/H | 112 | 1 | 0 | 999 | probably damaging | 0.998 | 32001 | likely deleterious | 32 |
869 | MYC | rs755460825 | SNP | missense variant | Q/K | 113 | 211 | 0.21 | 317 | benign | 0.316 | 23001 | likely benign | 23 |
870 | MYC | rs753250129 | SNP | missense variant | M/V | 116 | 661 | 0.66 | 758 | possibly damaging | 0.757 | 23001 | likely benign | 23 |
871 | MYC | rs758629773 | SNP | missense variant | M/I | 116 | 511 | 0.51 | 758 | possibly damaging | 0.757 | 24001 | likely benign | 24 |
872 | MYC | rs769538164 | SNP | missense variant | E/D | 119 | 211 | 0.21 | 996 | probably damaging | 0.995 | 24001 | likely benign | 24 |
873 | MYC | rs901466364 | SNP | missense variant | L/M | 121 | 11 | 0.01 | 998 | probably damaging | 0.997 | 25001 | likely benign | 25 |
874 | MYC | rs1010887246 | SNP | missense variant | N/K | 127 | 31 | 0.03 | 397 | benign | 0.396 | 25001 | likely benign | 25 |
875 | MYC | rs1264239026 | SNP | missense variant | Q/K | 128 | 81 | 0.08 | 921 | probably damaging | 0.92 | 24001 | likely benign | 24 |
876 | MYC | rs1300804558 | SNP | missense variant | S/R | 129 | 11 | 0.01 | 999 | probably damaging | 0.998 | 25001 | likely benign | 25 |
877 | MYC | rs748874520 | SNP | missense variant | F/C | 130 | 1 | 0 | 983 | probably damaging | 0.982 | 32001 | likely deleterious | 32 |
878 | MYC | rs959964647 | SNP | missense variant | F/L | 130 | 101 | 0.1 | 538 | possibly damaging | 0.537 | 25001 | likely benign | 25 |
879 | MYC | rs1478921898 | SNP | missense variant | D/N | 135 | 111 | 0.11 | 978 | probably damaging | 0.977 | 26001 | likely benign | 26 |
880 | MYC | rs993100973 | SNP | missense variant | D/G | 135 | 241 | 0.24 | 551 | possibly damaging | 0.55 | 25001 | likely benign | 25 |
881 | MYC | rs768286545 | SNP | missense variant | D/E | 135 | 371 | 0.37 | 695 | possibly damaging | 0.694 | 22001 | likely benign | 22 |
882 | MYC | rs768286545 | SNP | missense variant | D/E | 135 | 371 | 0.37 | 695 | possibly damaging | 0.694 | 22001 | likely benign | 22 |
883 | MYC | rs1454889513 | SNP | missense variant | D/N | 136 | 101 | 0.1 | 596 | possibly damaging | 0.595 | 25001 | likely benign | 25 |
884 | MYC | rs1284270835 | SNP | missense variant | D/E | 136 | 551 | 0.55 | 968 | probably damaging | 0.967 | 14001 | likely benign | 14 |
885 | MYC | rs1284270835 | SNP | missense variant | D/E | 136 | 551 | 0.55 | 968 | probably damaging | 0.967 | 14001 | likely benign | 14 |
886 | MYC | rs374225230 | SNP | missense variant | E/Q | 137 | 701 | 0.7 | 645 | possibly damaging | 0.644 | 24001 | likely benign | 24 |
887 | MYC | rs771723282 | SNP | missense variant | T/S | 138 | 831 | 0.83 | 31 | benign | 0.03 | 14001 | likely benign | 14 |
888 | MYC | rs773098170 | SNP | missense variant | T/S | 138 | 831 | 0.83 | 31 | benign | 0.03 | 14001 | likely benign | 14 |
889 | MYC | rs773098170 | SNP | missense variant | T/I | 138 | 31 | 0.03 | 787 | possibly damaging | 0.786 | 22001 | likely benign | 22 |
890 | MYC | rs1317807344 | SNP | missense variant | F/L | 139 | 291 | 0.29 | 280 | benign | 0.279 | 22001 | likely benign | 22 |
891 | MYC | rs1405976268 | SNP | missense variant | N/S | 142 | 1001 | 1 | 14 | benign | 0.013 | 23001 | likely benign | 23 |
892 | MYC | rs1032014837 | SNP | missense variant | I/V | 145 | 11 | 0.01 | 816 | possibly damaging | 0.815 | 26001 | likely benign | 26 |
893 | MYC | rs150308400 | SNP | missense variant | C/Y | 148 | 1 | 0 | 1000 | probably damaging | 0.999 | 32001 | likely deleterious | 32 |
894 | MYC | rs753906871 | SNP | missense variant | M/V | 149 | 1 | 0 | 969 | probably damaging | 0.968 | 28001 | likely benign | 28 |
895 | MYC | rs1248173307 | SNP | missense variant | G/S | 152 | 101 | 0.1 | 916 | probably damaging | 0.915 | 27001 | likely benign | 27 |
896 | MYC | rs1468408630 | SNP | missense variant | G/A | 152 | 31 | 0.03 | 971 | probably damaging | 0.97 | 31001 | likely deleterious | 31 |
897 | MYC | rs1161084627 | SNP | missense variant | A/S | 157 | 71 | 0.07 | 995 | probably damaging | 0.994 | 27001 | likely benign | 27 |
898 | MYC | rs913059216 | SNP | missense variant | K/R | 158 | 31 | 0.03 | 938 | probably damaging | 0.937 | 25001 | likely benign | 25 |
899 | MYC | rs137906262 | SNP | missense variant | L/I | 159 | 11 | 0.01 | 998 | probably damaging | 0.997 | 28001 | likely benign | 28 |
900 | MYC | rs753094370 | SNP | missense variant | V/A | 160 | 1 | 0 | 976 | probably damaging | 0.975 | 32001 | likely deleterious | 32 |
901 | MYC | rs1324784102 | SNP | missense variant | E/Q | 162 | 1 | 0 | 985 | probably damaging | 0.984 | 32001 | likely deleterious | 32 |
902 | MYC | rs758986453 | SNP | missense variant | E/D | 162 | 1 | 0 | 968 | probably damaging | 0.967 | 26001 | likely benign | 26 |
903 | MYC | rs777980347 | SNP | missense variant | S/F | 166 | 21 | 0.02 | 976 | probably damaging | 0.975 | 28001 | likely benign | 28 |
904 | MYC | rs61755060 | SNP | missense variant | Q/H | 168 | 291 | 0.29 | 156 | benign | 0.155 | 24001 | likely benign | 24 |
905 | MYC | rs1374279390 | SNP | missense variant | A/T | 170 | 51 | 0.05 | 31 | benign | 0.03 | 26001 | likely benign | 26 |
906 | MYC | rs990645227 | SNP | missense variant | R/L | 171 | 21 | 0.02 | 967 | probably damaging | 0.966 | 32001 | likely deleterious | 32 |
907 | MYC | rs755827927 | SNP | missense variant | K/Q | 172 | 101 | 0.1 | 972 | probably damaging | 0.971 | 23001 | likely benign | 23 |
908 | MYC | rs755827927 | SNP | missense variant | K/E | 172 | 111 | 0.11 | 916 | probably damaging | 0.915 | 23001 | likely benign | 23 |
909 | MYC | rs967161771 | SNP | missense variant | D/N | 173 | 141 | 0.14 | 947 | probably damaging | 0.946 | 27001 | likely benign | 27 |
910 | MYC | rs748962740 | SNP | missense variant | D/E | 173 | 941 | 0.94 | 240 | benign | 0.239 | 23001 | likely benign | 23 |
911 | MYC | rs1291924699 | SNP | missense variant | S/G | 174 | 541 | 0.54 | 10 | benign | 0.009 | 19001 | likely benign | 19 |
912 | MYC | rs1436063286 | SNP | missense variant | S/R | 174 | 381 | 0.38 | 587 | possibly damaging | 0.586 | 23001 | likely benign | 23 |
913 | MYC | rs4645960 | SNP | missense variant | G/S | 175 | 381 | 0.38 | 2 | benign | 0.001 | 11001 | likely benign | 11 |
914 | MYC | rs4645960 | SNP | missense variant | G/R | 175 | 111 | 0.11 | 270 | benign | 0.269 | 17001 | likely benign | 17 |
915 | MYC | rs4645960 | SNP | missense variant | G/C | 175 | 181 | 0.18 | 49 | benign | 0.048 | 19001 | likely benign | 19 |
916 | MYC | rs1458778798 | SNP | missense variant | P/T | 177 | 361 | 0.36 | 16 | benign | 0.015 | 19001 | likely benign | 19 |
917 | MYC | rs1458778798 | SNP | missense variant | P/A | 177 | 1001 | 1 | 8 | benign | 0.007 | 15001 | likely benign | 15 |
918 | MYC | rs1384004800 | SNP | missense variant | N/K | 178 | 681 | 0.68 | 27 | benign | 0.026 | 15001 | likely benign | 15 |
919 | MYC | rs1439970381 | SNP | missense variant | P/S | 179 | 591 | 0.59 | 921 | probably damaging | 0.92 | 18001 | likely benign | 18 |
920 | MYC | rs1164555124 | SNP | missense variant | A/S | 180 | 311 | 0.31 | 136 | benign | 0.135 | 18001 | likely benign | 18 |
921 | MYC | rs1416564094 | SNP | missense variant | A/V | 180 | 81 | 0.08 | 601 | possibly damaging | 0.6 | 21001 | likely benign | 21 |
922 | MYC | rs772094171 | SNP | missense variant | R/G | 181 | 411 | 0.41 | 4 | benign | 0.003 | 22001 | likely benign | 22 |
923 | MYC | rs772094171 | SNP | missense variant | R/C | 181 | 61 | 0.06 | 782 | possibly damaging | 0.781 | 25001 | likely benign | 25 |
924 | MYC | rs1328542776 | SNP | missense variant | R/H | 181 | 121 | 0.12 | 704 | possibly damaging | 0.703 | 25001 | likely benign | 25 |
925 | MYC | rs772869147 | SNP | missense variant | G/S | 182 | 381 | 0.38 | 19 | benign | 0.018 | 21001 | likely benign | 21 |
926 | MYC | rs1449189337 | SNP | missense variant | G/V | 182 | 101 | 0.1 | 11 | benign | 0.01 | 19001 | likely benign | 19 |
927 | MYC | rs770713291 | SNP | missense variant | S/G | 184 | 611 | 0.61 | 11 | benign | 0.01 | 11001 | likely benign | 11 |
928 | MYC | rs1414103970 | SNP | missense variant | S/R | 184 | 481 | 0.48 | 855 | possibly damaging | 0.854 | 18001 | likely benign | 18 |
929 | MYC | rs4645961 | SNP | missense variant | V/I | 185 | 211 | 0.21 | 249 | benign | 0.248 | 19001 | likely benign | 19 |
930 | MYC | rs1286064895 | SNP | missense variant | C/S | 186 | 791 | 0.79 | 8 | benign | 0.007 | 23001 | likely benign | 23 |
931 | MYC | rs1469075079 | SNP | missense variant | T/I | 188 | 241 | 0.24 | 133 | benign | 0.132 | 24001 | likely benign | 24 |
932 | MYC | rs759774541 | SNP | missense variant | S/Y | 189 | 221 | 0.22 | 360 | benign | 0.359 | 24001 | likely benign | 24 |
933 | MYC | rs1273381542 | SNP | missense variant | L/S | 191 | 761 | 0.76 | 79 | benign | 0.078 | 23001 | likely benign | 23 |
934 | MYC | rs1273381542 | SNP | missense variant | L/W | 191 | 21 | 0.02 | 981 | probably damaging | 0.98 | 26001 | likely benign | 26 |
935 | MYC | rs775690959 | SNP | missense variant | Q/P | 194 | 81 | 0.08 | 121 | benign | 0.12 | 25001 | likely benign | 25 |
936 | MYC | rs775690959 | SNP | missense variant | Q/R | 194 | 201 | 0.2 | 884 | possibly damaging | 0.883 | 25001 | likely benign | 25 |
937 | MYC | rs1474679499 | SNP | missense variant | A/T | 200 | 41 | 0.04 | 330 | benign | 0.329 | 25001 | likely benign | 25 |
938 | MYC | rs1425055091 | SNP | missense variant | E/K | 202 | 11 | 0.01 | 921 | probably damaging | 0.92 | 29001 | likely benign | 29 |
939 | MYC | rs1467496891 | SNP | missense variant | C/Y | 203 | 1 | 0 | 1000 | probably damaging | 0.999 | 32001 | likely deleterious | 32 |
940 | MYC | rs1174781741 | SNP | missense variant | I/T | 204 | 1 | 0 | 969 | probably damaging | 0.968 | 32001 | likely deleterious | 32 |
941 | MYC | rs1194568592 | SNP | missense variant | P/L | 206 | 21 | 0.02 | 991 | probably damaging | 0.99 | 32001 | likely deleterious | 32 |
942 | MYC | rs1221801220 | SNP | missense variant | P/R | 213 | 1 | 0 | 1001 | probably damaging | 1 | 26001 | likely benign | 26 |
943 | MYC | rs1429861982 | SNP | missense variant | L/F | 214 | 41 | 0.04 | 983 | probably damaging | 0.982 | 25001 | likely benign | 25 |
944 | MYC | rs753502487 | SNP | missense variant | N/K | 215 | 561 | 0.56 | 69 | benign | 0.068 | 14001 | likely benign | 14 |
945 | MYC | rs577698378 | SNP | missense variant | D/N | 216 | 71 | 0.07 | 653 | possibly damaging | 0.652 | 23001 | likely benign | 23 |
946 | MYC | rs778262855 | SNP | missense variant | D/G | 216 | 121 | 0.12 | 536 | possibly damaging | 0.535 | 22001 | likely benign | 22 |
947 | MYC | rs922203242 | SNP | missense variant | S/N | 217 | 341 | 0.34 | 833 | possibly damaging | 0.832 | 18001 | likely benign | 18 |
948 | MYC | rs754835412 | SNP | missense variant | S/P | 219 | 291 | 0.29 | 215 | benign | 0.214 | 22001 | likely benign | 22 |
949 | MYC | rs112602073 | SNP | missense variant | P/S | 220 | 41 | 0.04 | 136 | benign | 0.135 | 24001 | likely benign | 24 |
950 | MYC | rs1041258616 | SNP | missense variant | P/R | 220 | 41 | 0.04 | 902 | possibly damaging | 0.901 | 25001 | likely benign | 25 |
951 | MYC | rs758263761 | SNP | missense variant | K/R | 221 | 441 | 0.44 | 269 | benign | 0.268 | 23001 | likely benign | 23 |
952 | MYC | rs933579368 | SNP | missense variant | K/N | 221 | 331 | 0.33 | 19 | benign | 0.018 | 22001 | likely benign | 22 |
953 | MYC | rs777695894 | SNP | missense variant | S/T | 222 | 591 | 0.59 | 32 | benign | 0.031 | 10001 | likely benign | 10 |
954 | MYC | rs1264499327 | SNP | missense variant | A/T | 224 | 251 | 0.25 | 4 | benign | 0.003 | 6001 | likely benign | 6 |
955 | MYC | rs746958042 | SNP | missense variant | A/V | 224 | 201 | 0.2 | 117 | benign | 0.116 | 21001 | likely benign | 21 |
956 | MYC | rs770660324 | SNP | missense variant | S/P | 225 | 171 | 0.17 | 8 | benign | 0.007 | 24001 | likely benign | 24 |
957 | MYC | rs776438693 | SNP | missense variant | S/L | 225 | 141 | 0.14 | 8 | benign | 0.007 | 23001 | likely benign | 23 |
958 | MYC | rs1174543892 | SNP | missense variant | D/N | 227 | 471 | 0.47 | 107 | benign | 0.106 | 20001 | likely benign | 20 |
959 | MYC | rs370338821 | SNP | missense variant | S/F | 228 | 61 | 0.06 | 448 | possibly damaging | 0.447 | 23001 | likely benign | 23 |
960 | MYC | rs1166344892 | SNP | missense variant | S/R | 229 | 511 | 0.51 | 58 | benign | 0.057 | 11001 | likely benign | 11 |
961 | MYC | rs775427980 | SNP | missense variant | S/T | 229 | 651 | 0.65 | 1 | benign | 0 | 5001 | likely benign | 5 |
962 | MYC | rs1476455361 | SNP | missense variant | A/T | 230 | 231 | 0.23 | 1 | benign | 0 | 13001 | likely benign | 13 |
963 | MYC | rs544792311 | SNP | missense variant | A/V | 230 | 201 | 0.2 | 1 | benign | 0 | 16001 | likely benign | 16 |
964 | MYC | rs1020933770 | SNP | missense variant | S/P | 232 | 221 | 0.22 | 14 | benign | 0.013 | 24001 | likely benign | 24 |
965 | MYC | rs147506213 | SNP | missense variant | P/T | 233 | 211 | 0.21 | 2 | benign | 0.001 | 1 | likely benign | 0 |
966 | MYC | rs147506213 | SNP | missense variant | P/A | 233 | 271 | 0.27 | 1 | benign | 0 | 1 | likely benign | 0 |
967 | MYC | rs147506213 | SNP | missense variant | P/S | 233 | 321 | 0.32 | 1 | benign | 0 | 1 | likely benign | 0 |
968 | MYC | rs1221550924 | SNP | missense variant | P/Q | 233 | 181 | 0.18 | 105 | benign | 0.104 | 19001 | likely benign | 19 |
969 | MYC | rs1221550924 | SNP | missense variant | P/L | 233 | 111 | 0.11 | 1 | benign | 0 | 20001 | likely benign | 20 |
970 | MYC | rs765003654 | SNP | missense variant | L/V | 239 | 541 | 0.54 | 377 | benign | 0.376 | 23001 | likely benign | 23 |
971 | MYC | rs1000455991 | SNP | missense variant | S/A | 240 | 591 | 0.59 | 63 | benign | 0.062 | 23001 | likely benign | 23 |
972 | MYC | rs1328290024 | SNP | missense variant | S/P | 241 | 171 | 0.17 | 11 | benign | 0.01 | 25001 | likely benign | 25 |
973 | MYC | rs186663828 | SNP | missense variant | S/L | 241 | 131 | 0.13 | 271 | benign | 0.27 | 24001 | likely benign | 24 |
974 | MYC | rs1434118612 | SNP | missense variant | E/K | 243 | 831 | 0.83 | 16 | benign | 0.015 | 22001 | likely benign | 22 |
975 | MYC | rs1489420810 | SNP | missense variant | E/V | 243 | 271 | 0.27 | 16 | benign | 0.015 | 22001 | likely benign | 22 |
976 | MYC | rs374701735 | SNP | missense variant | E/D | 243 | 581 | 0.58 | 29 | benign | 0.028 | 20001 | likely benign | 20 |
977 | MYC | rs545330879 | SNP | missense variant | P/Q | 246 | 101 | 0.1 | 657 | possibly damaging | 0.656 | 23001 | likely benign | 23 |
978 | MYC | rs545330879 | SNP | missense variant | P/R | 246 | 141 | 0.14 | 584 | possibly damaging | 0.583 | 23001 | likely benign | 23 |
979 | MYC | rs545330879 | SNP | missense variant | P/L | 246 | 41 | 0.04 | 274 | benign | 0.273 | 24001 | likely benign | 24 |
980 | MYC | rs1362563336 | SNP | missense variant | G/D | 248 | 551 | 0.55 | 60 | benign | 0.059 | 17001 | likely benign | 17 |
981 | MYC | rs1362563336 | SNP | missense variant | G/V | 248 | 431 | 0.43 | 16 | benign | 0.015 | 18001 | likely benign | 18 |
982 | MYC | rs772761233 | SNP | missense variant | S/N | 249 | 191 | 0.19 | 7 | benign | 0.006 | 21001 | likely benign | 21 |
983 | MYC | rs1367173254 | SNP | missense variant | P/L | 250 | 171 | 0.17 | 148 | benign | 0.147 | 23001 | likely benign | 23 |
984 | MYC | rs766666917 | SNP | missense variant | E/K | 251 | 671 | 0.67 | 4 | benign | 0.003 | 17001 | likely benign | 17 |
985 | MYC | rs752344761 | SNP | missense variant | P/H | 252 | 91 | 0.09 | 4 | benign | 0.003 | 22001 | likely benign | 22 |
986 | MYC | rs763627051 | SNP | missense variant | L/P | 253 | 291 | 0.29 | 534 | possibly damaging | 0.533 | 16001 | likely benign | 16 |
987 | MYC | rs751130055 | SNP | missense variant | V/M | 254 | 171 | 0.17 | 2 | benign | 0.001 | 21001 | likely benign | 21 |
988 | MYC | rs757183481 | SNP | missense variant | L/F | 255 | 711 | 0.71 | 963 | probably damaging | 0.962 | 18001 | likely benign | 18 |
989 | MYC | rs781041285 | SNP | missense variant | H/D | 256 | 651 | 0.65 | 30 | benign | 0.029 | 17001 | likely benign | 17 |
990 | MYC | rs750374321 | SNP | missense variant | H/P | 256 | 291 | 0.29 | 1 | benign | 0 | 17001 | likely benign | 17 |
991 | MYC | rs750374321 | SNP | missense variant | H/R | 256 | 501 | 0.5 | 30 | benign | 0.029 | 15001 | likely benign | 15 |
992 | MYC | rs779748283 | SNP | missense variant | H/Q | 256 | 561 | 0.56 | 4 | benign | 0.003 | 3001 | likely benign | 3 |
993 | MYC | rs1467095827 | SNP | missense variant | E/K | 258 | 121 | 0.12 | 110 | benign | 0.109 | 23001 | likely benign | 23 |
994 | MYC | rs1057519851 | SNP | missense variant | P/A | 260 | 561 | 0.56 | 326 | benign | 0.325 | 22001 | likely benign | 22 |
995 | MYC | rs749498067 | SNP | missense variant | P/Q | 260 | 411 | 0.41 | 102 | benign | 0.101 | 23001 | likely benign | 23 |
996 | MYC | rs1020542388 | SNP | missense variant | T/I | 263 | 31 | 0.03 | 226 | benign | 0.225 | 26001 | likely benign | 26 |
997 | MYC | rs1159672918 | SNP | missense variant | S/C | 264 | 91 | 0.09 | 907 | possibly damaging | 0.906 | 25001 | likely benign | 25 |
998 | MYC | rs1442840229 | SNP | missense variant | S/I | 264 | 91 | 0.09 | 879 | possibly damaging | 0.878 | 26001 | likely benign | 26 |
999 | MYC | rs1209695374 | SNP | missense variant | E/D | 269 | 191 | 0.19 | 35 | benign | 0.034 | 21001 | likely benign | 21 |
1000 | MYC | rs977518778 | SNP | missense variant | E/K | 274 | 11 | 0.01 | 170 | benign | 0.169 | 28001 | likely benign | 28 |
1001 | MYC | rs1358102215 | SNP | missense variant | D/N | 278 | 1 | 0 | 999 | probably damaging | 0.998 | 32001 | likely deleterious | 32 |
1002 | MYC | rs1195526437 | SNP | missense variant | V/L | 280 | 1 | 0 | 995 | probably damaging | 0.994 | 28001 | likely benign | 28 |
1003 | MYC | rs1426971261 | SNP | missense variant | V/M | 282 | 1 | 0 | 908 | possibly damaging | 0.907 | 31001 | likely deleterious | 31 |
1004 | MYC | rs1355624510 | SNP | missense variant | V/A | 282 | 11 | 0.01 | 649 | possibly damaging | 0.648 | 29001 | likely benign | 29 |
1005 | MYC | rs1413496327 | SNP | missense variant | E/G | 283 | 1 | 0 | 105 | benign | 0.104 | 32001 | likely deleterious | 32 |
1006 | MYC | rs755221038 | SNP | missense variant | K/M | 284 | 1 | 0 | 232 | benign | 0.231 | 29001 | likely benign | 29 |
1007 | MYC | rs756770497 | SNP | missense variant | K/N | 284 | 1 | 0 | 776 | possibly damaging | 0.775 | 28001 | likely benign | 28 |
1008 | MYC | rs1563758692 | SNP | missense variant | R/K | 285 | 21 | 0.02 | 343 | benign | 0.342 | 28001 | likely benign | 28 |
1009 | MYC | rs1437137562 | SNP | missense variant | Q/E | 286 | 191 | 0.19 | 138 | benign | 0.137 | 23001 | likely benign | 23 |
1010 | MYC | rs772229477 | SNP | missense variant | Q/L | 286 | 21 | 0.02 | 8 | benign | 0.007 | 28001 | likely benign | 28 |
1011 | MYC | rs778030574 | SNP | missense variant | G/C | 289 | 31 | 0.03 | 7 | benign | 0.006 | 23001 | likely benign | 23 |
1012 | MYC | rs747518067 | SNP | missense variant | E/V | 293 | 331 | 0.33 | 20 | benign | 0.019 | 24001 | likely benign | 24 |
1013 | MYC | rs562953156 | SNP | missense variant | S/L | 296 | 71 | 0.07 | 345 | benign | 0.344 | 22001 | likely benign | 22 |
1014 | MYC | rs150629172 | SNP | missense variant | P/H | 297 | 181 | 0.18 | 1 | benign | 0 | 14001 | likely benign | 14 |
1015 | MYC | rs770159089 | SNP | missense variant | A/S | 299 | 941 | 0.94 | 2 | benign | 0.001 | 1 | likely benign | 0 |
1016 | MYC | rs372210680 | SNP | missense variant | G/D | 301 | 291 | 0.29 | 4 | benign | 0.003 | 19001 | likely benign | 19 |
1017 | MYC | rs1285441185 | SNP | missense variant | H/R | 302 | 361 | 0.36 | 230 | benign | 0.229 | 16001 | likely benign | 16 |
1018 | MYC | rs139697494 | SNP | missense variant | H/Q | 302 | 291 | 0.29 | 42 | benign | 0.041 | 16001 | likely benign | 16 |
1019 | MYC | rs766987302 | SNP | missense variant | S/R | 303 | 311 | 0.31 | 161 | benign | 0.16 | 20001 | likely benign | 20 |
1020 | MYC | rs772650309 | SNP | missense variant | K/I | 304 | 11 | 0.01 | 406 | benign | 0.405 | 23001 | likely benign | 23 |
1021 | MYC | rs760650253 | SNP | missense variant | P/H | 305 | 141 | 0.14 | 972 | probably damaging | 0.971 | 22001 | likely benign | 22 |
1022 | MYC | rs760650253 | SNP | missense variant | P/R | 305 | 91 | 0.09 | 963 | probably damaging | 0.962 | 22001 | likely benign | 22 |
1023 | MYC | rs766292378 | SNP | missense variant | P/L | 306 | 161 | 0.16 | 6 | benign | 0.005 | 22001 | likely benign | 22 |
1024 | MYC | rs781657156 | SNP | missense variant | L/P | 312 | 1 | 0 | 985 | probably damaging | 0.984 | 32001 | likely deleterious | 32 |
1025 | MYC | rs1157474201 | SNP | missense variant | K/R | 313 | 11 | 0.01 | 995 | probably damaging | 0.994 | 31001 | likely deleterious | 31 |
1026 | MYC | rs1380388393 | SNP | missense variant | R/W | 314 | 21 | 0.02 | 1000 | probably damaging | 0.999 | 23001 | likely benign | 23 |
1027 | MYC | rs1179847000 | SNP | missense variant | C/F | 315 | 1 | 0 | 936 | probably damaging | 0.935 | 31001 | likely deleterious | 31 |
1028 | MYC | rs1051420663 | SNP | missense variant | H/R | 316 | 41 | 0.04 | 998 | probably damaging | 0.997 | 28001 | likely benign | 28 |
1029 | MYC | rs752926420 | SNP | missense variant | V/F | 317 | 21 | 0.02 | 980 | probably damaging | 0.979 | 29001 | likely benign | 29 |
1030 | MYC | rs1490057941 | SNP | missense variant | S/C | 318 | 51 | 0.05 | 795 | possibly damaging | 0.794 | 24001 | likely benign | 24 |
1031 | MYC | rs903134011 | SNP | missense variant | H/L | 320 | 11 | 0.01 | 919 | probably damaging | 0.918 | 28001 | likely benign | 28 |
1032 | MYC | rs146971340 | SNP | missense variant | H/Q | 320 | 561 | 0.56 | 328 | benign | 0.327 | 10001 | likely benign | 10 |
1033 | MYC | rs781494801 | SNP | missense variant | P/S | 327 | 121 | 0.12 | 69 | benign | 0.068 | 20001 | likely benign | 20 |
1034 | MYC | rs1354508987 | SNP | missense variant | P/A | 328 | 51 | 0.05 | 998 | probably damaging | 0.997 | 23001 | likely benign | 23 |
1035 | MYC | rs1272045308 | SNP | missense variant | S/P | 329 | 231 | 0.23 | 975 | probably damaging | 0.974 | 23001 | likely benign | 23 |
1036 | MYC | rs746409847 | SNP | missense variant | T/P | 330 | 81 | 0.08 | 906 | possibly damaging | 0.905 | 25001 | likely benign | 25 |
1037 | MYC | rs746409847 | SNP | missense variant | T/A | 330 | 111 | 0.11 | 407 | benign | 0.406 | 24001 | likely benign | 24 |
1038 | MYC | rs184271012 | SNP | missense variant | R/W | 331 | 1 | 0 | 901 | possibly damaging | 0.9 | 23001 | likely benign | 23 |
1039 | MYC | rs772772048 | SNP | missense variant | R/Q | 331 | 41 | 0.04 | 238 | benign | 0.237 | 31001 | likely deleterious | 31 |
1040 | MYC | rs1479419101 | SNP | missense variant | P/T | 335 | 1 | 0 | 914 | probably damaging | 0.913 | 24001 | likely benign | 24 |
1041 | MYC | rs1177628089 | SNP | missense variant | P/L | 335 | 1 | 0 | 767 | possibly damaging | 0.766 | 23001 | likely benign | 23 |
1042 | MYC | rs1378948166 | SNP | missense variant | A/S | 337 | 171 | 0.17 | 29 | benign | 0.028 | 16001 | likely benign | 16 |
1043 | MYC | rs4645968 | SNP | missense variant | A/V | 337 | 1001 | 1 | 10 | benign | 0.009 | 20001 | likely benign | 20 |
1044 | MYC | rs893110546 | SNP | missense variant | K/R | 341 | 281 | 0.28 | 7 | benign | 0.006 | 22001 | likely benign | 22 |
1045 | MYC | rs765924453 | SNP | missense variant | D/N | 343 | 91 | 0.09 | 965 | probably damaging | 0.964 | 24001 | likely benign | 24 |
1046 | MYC | rs776379651 | SNP | missense variant | D/E | 343 | 1001 | 1 | 184 | benign | 0.183 | 19001 | likely benign | 19 |
1047 | MYC | rs1236689606 | SNP | missense variant | S/G | 344 | 181 | 0.18 | 4 | benign | 0.003 | 24001 | likely benign | 24 |
1048 | MYC | rs773571686 | SNP | missense variant | S/N | 344 | 161 | 0.16 | 16 | benign | 0.015 | 22001 | likely benign | 22 |
1049 | MYC | rs773571686 | SNP | missense variant | S/I | 344 | 41 | 0.04 | 736 | possibly damaging | 0.735 | 26001 | likely benign | 26 |
1050 | MYC | rs752586995 | SNP | missense variant | R/T | 346 | 61 | 0.06 | 390 | benign | 0.389 | 23001 | likely benign | 23 |
1051 | MYC | rs758679560 | SNP | missense variant | R/T | 349 | 11 | 0.01 | 1 | benign | 0 | 23001 | likely benign | 23 |
1052 | MYC | rs764346243 | SNP | missense variant | I/M | 351 | 11 | 0.01 | 998 | probably damaging | 0.997 | 26001 | likely benign | 26 |
1053 | MYC | rs1013179067 | SNP | missense variant | S/T | 352 | 281 | 0.28 | 916 | probably damaging | 0.915 | 23001 | likely benign | 23 |
1054 | MYC | rs1313047247 | SNP | missense variant | N/K | 354 | 411 | 0.41 | 998 | probably damaging | 0.997 | 23001 | likely benign | 23 |
1055 | MYC | rs1415460536 | SNP | missense variant | K/E | 356 | 1 | 0 | 170 | benign | 0.169 | 25001 | likely benign | 25 |
1056 | MYC | rs1355490965 | SNP | missense variant | C/S | 357 | 501 | 0.5 | 997 | probably damaging | 0.996 | 24001 | likely benign | 24 |
1057 | MYC | rs1355490965 | SNP | missense variant | C/G | 357 | 31 | 0.03 | 997 | probably damaging | 0.996 | 29001 | likely benign | 29 |
1058 | MYC | rs1012972478 | SNP | missense variant | C/Y | 357 | 1 | 0 | 999 | probably damaging | 0.998 | 32001 | likely deleterious | 32 |
1059 | MYC | rs1012972478 | SNP | missense variant | C/F | 357 | 1 | 0 | 998 | probably damaging | 0.997 | 32001 | likely deleterious | 32 |
1060 | MYC | rs1480367143 | SNP | missense variant | S/N | 359 | 1 | 0 | 998 | probably damaging | 0.997 | 30001 | likely deleterious | 30 |
1061 | MYC | rs751822114 | SNP | missense variant | R/G | 361 | 31 | 0.03 | 997 | probably damaging | 0.996 | 23001 | likely benign | 23 |
1062 | MYC | rs1024952766 | SNP | missense variant | R/S | 361 | 1 | 0 | 997 | probably damaging | 0.996 | 26001 | likely benign | 26 |
1063 | MYC | rs200431478 | SNP | missense variant | S/C | 362 | 11 | 0.01 | 936 | probably damaging | 0.935 | 27001 | likely benign | 27 |
1064 | MYC | rs200431478 | SNP | missense variant | S/F | 362 | 1 | 0 | 915 | probably damaging | 0.914 | 27001 | likely benign | 27 |
1065 | MYC | rs1197838517 | SNP | missense variant | D/N | 364 | 1 | 0 | 999 | probably damaging | 0.998 | 25001 | likely benign | 25 |
1066 | MYC | rs746333391 | SNP | missense variant | D/V | 364 | 1 | 0 | 1000 | probably damaging | 0.999 | 27001 | likely benign | 27 |
1067 | MYC | rs756666851 | SNP | missense variant | E/K | 366 | 1 | 0 | 998 | probably damaging | 0.997 | 32001 | likely deleterious | 32 |
1068 | MYC | rs749722454 | SNP | missense variant | E/K | 367 | 11 | 0.01 | 737 | possibly damaging | 0.736 | 32001 | likely deleterious | 32 |
1069 | MYC | rs769010031 | SNP | missense variant | N/T | 368 | 21 | 0.02 | 311 | benign | 0.31 | 26001 | likely benign | 26 |
1070 | MYC | rs878873271 | SNP | missense variant | R/Q | 372 | 11 | 0.01 | 964 | probably damaging | 0.963 | 32001 | likely deleterious | 32 |
1071 | MYC | rs878873271 | SNP | missense variant | R/L | 372 | 21 | 0.02 | 769 | possibly damaging | 0.768 | 32001 | likely deleterious | 32 |
1072 | MYC | rs777230092 | SNP | missense variant | N/K | 375 | 1 | 0 | 1000 | probably damaging | 0.999 | 24001 | likely benign | 24 |
1073 | MYC | rs1276187525 | SNP | missense variant | V/I | 376 | 471 | 0.47 | 306 | benign | 0.305 | 24001 | likely benign | 24 |
1074 | MYC | rs1401250556 | SNP | missense variant | Q/H | 380 | 1 | 0 | 999 | probably damaging | 0.998 | 27001 | likely benign | 27 |
1075 | MYC | rs776244909 | SNP | missense variant | R/Q | 387 | 31 | 0.03 | 370 | benign | 0.369 | 32001 | likely deleterious | 32 |
1076 | MYC | rs1460956206 | SNP | missense variant | F/C | 390 | 1 | 0 | 981 | probably damaging | 0.98 | 32001 | likely deleterious | 32 |
1077 | MYC | rs771168413 | SNP | missense variant | D/H | 394 | 1 | 0 | 1000 | probably damaging | 0.999 | 32001 | likely deleterious | 32 |
1078 | MYC | rs771168413 | SNP | missense variant | D/Y | 394 | 21 | 0.02 | 1000 | probably damaging | 0.999 | 32001 | likely deleterious | 32 |
1079 | MYC | rs141095253 | SNP | missense variant | P/L | 397 | 31 | 0.03 | 1000 | probably damaging | 0.999 | 28001 | likely benign | 28 |
1080 | MYC | rs762139580 | SNP | missense variant | A/S | 405 | 11 | 0.01 | 998 | probably damaging | 0.997 | 29001 | likely benign | 29 |
1081 | MYC | rs1442494202 | SNP | missense variant | P/S | 406 | 131 | 0.13 | 174 | benign | 0.173 | 22001 | likely benign | 22 |
1082 | MYC | rs767477446 | SNP | missense variant | K/I | 412 | 1 | 0 | 985 | probably damaging | 0.984 | 29001 | likely benign | 29 |
1083 | MYC | rs750562100 | SNP | missense variant | T/I | 415 | 41 | 0.04 | 863 | possibly damaging | 0.862 | 25001 | likely benign | 25 |
1084 | MYC | rs756611896 | SNP | missense variant | A/T | 416 | 11 | 0.01 | 1 | benign | 0 | 18001 | likely benign | 18 |
1085 | MYC | rs1193335325 | SNP | missense variant | A/V | 416 | 11 | 0.01 | 1 | benign | 0 | 22001 | likely benign | 22 |
1086 | MYC | rs755283006 | SNP | missense variant | V/I | 421 | 871 | 0.87 | 1 | benign | 0 | 1 | likely benign | 0 |
1087 | MYC | rs1332562282 | SNP | missense variant | A/T | 423 | 251 | 0.25 | 4 | benign | 0.003 | 16001 | likely benign | 16 |
1088 | MYC | rs1415084652 | SNP | missense variant | E/A | 424 | 11 | 0.01 | 54 | benign | 0.053 | 23001 | likely benign | 23 |
1089 | MYC | rs1336293145 | SNP | missense variant | E/G | 425 | 1 | 0 | 711 | possibly damaging | 0.71 | 32001 | likely deleterious | 32 |
1090 | MYC | rs746611175 | SNP | missense variant | L/F | 428 | 1 | 0 | 1000 | probably damaging | 0.999 | 26001 | likely benign | 26 |
1091 | MYC | rs1389942859 | SNP | missense variant | E/K | 432 | 1001 | 1 | 1 | benign | 0 | 19001 | likely benign | 19 |
1092 | MYC | rs553965730 | SNP | missense variant | D/G | 433 | 11 | 0.01 | 20 | benign | 0.019 | 25001 | likely benign | 25 |
1093 | MYC | rs145561065 | SNP | missense variant | L/F | 434 | 31 | 0.03 | 101 | benign | 0.1 | 19001 | likely benign | 19 |
1094 | MYC | rs145561065 | SNP | missense variant | L/F | 434 | 31 | 0.03 | 101 | benign | 0.1 | 19001 | likely benign | 19 |
1095 | MYC | rs774254150 | SNP | missense variant | R/W | 436 | 1 | 0 | 630 | possibly damaging | 0.629 | 23001 | likely benign | 23 |
1096 | MYC | rs761932135 | SNP | missense variant | R/Q | 436 | 461 | 0.46 | 6 | benign | 0.005 | 24001 | likely benign | 24 |
1097 | MYC | rs1465173750 | SNP | missense variant | R/Q | 438 | 11 | 0.01 | 105 | benign | 0.104 | 24001 | likely benign | 24 |
1098 | MYC | rs148863193 | SNP | missense variant | R/Q | 439 | 591 | 0.59 | 8 | benign | 0.007 | 22001 | likely benign | 22 |
1099 | MYC | rs148863193 | SNP | missense variant | R/L | 439 | 121 | 0.12 | 194 | benign | 0.193 | 23001 | likely benign | 23 |
1100 | MYC | rs750651389 | SNP | missense variant | E/V | 440 | 1 | 0 | 383 | benign | 0.382 | 27001 | likely benign | 27 |
1101 | MYC | rs760686595 | SNP | missense variant | L/F | 442 | 1 | 0 | 1000 | probably damaging | 0.999 | 23001 | likely benign | 23 |
1102 | MYC | rs370767192 | SNP | missense variant | H/Y | 444 | 31 | 0.03 | 37 | benign | 0.036 | 23001 | likely benign | 23 |
1103 | MYC | rs754298537 | SNP | missense variant | K/E | 445 | 1 | 0 | 292 | benign | 0.291 | 25001 | likely benign | 25 |
1104 | MYC | rs755545316 | SNP | missense variant | E/G | 447 | 11 | 0.01 | 155 | benign | 0.154 | 24001 | likely benign | 24 |
1105 | MYC | rs1478499127 | SNP | missense variant | Q/R | 448 | 181 | 0.18 | 7 | benign | 0.006 | 23001 | likely benign | 23 |
1106 | MYC | rs779123478 | SNP | missense variant | R/G | 450 | 1 | 0 | 458 | possibly damaging | 0.457 | 26001 | likely benign | 26 |
1107 | MYC | rs779123478 | SNP | missense variant | R/W | 450 | 1 | 0 | 863 | possibly damaging | 0.862 | 29001 | likely benign | 29 |
1108 | MYC | rs201337668 | SNP | missense variant | C/G | 453 | 631 | 0.63 | 1 | benign | 0 | 18001 | likely benign | 18 |
1109 | MYC | rs536396530 | SNP | missense variant | C/S | 453 | 701 | 0.7 | 10 | benign | 0.009 | 19001 | likely benign | 19 |
1110 | MYC | rs536396530 | SNP | missense variant | C/F | 453 | 141 | 0.14 | 82 | benign | 0.081 | 22001 | likely benign | 22 |
1111 | MYC | rs143501729 | SNP | missense variant | A/E | 454 | 1 | 0 | 15 | benign | 0.014 | 22001 | likely benign | 22 |
1112 | CCND1 | rs572037183 | SNP | missense variant | E/K | 2 | 141 | 0.14 | 13 | benign | 0.012 | 23001 | likely benign | 23 |
1113 | CCND1 | rs572037183 | SNP | missense variant | E/Q | 2 | 171 | 0.17 | 52 | benign | 0.051 | 23001 | likely benign | 23 |
1114 | CCND1 | rs545664320 | SNP | missense variant | H/R | 3 | 151 | 0.15 | 24 | benign | 0.023 | 21001 | likely benign | 21 |
1115 | CCND1 | rs1356268873 | SNP | missense variant | Q/H | 4 | 1 | 0 | 309 | benign | 0.308 | 24001 | likely benign | 24 |
1116 | CCND1 | rs993495966 | SNP | missense variant | C/S | 7 | 1 | 0 | 980 | probably damaging | 0.979 | 28001 | likely benign | 28 |
1117 | CCND1 | rs993495966 | SNP | missense variant | C/R | 7 | 1 | 0 | 995 | probably damaging | 0.994 | 31001 | likely deleterious | 31 |
1118 | CCND1 | rs1486252402 | SNP | missense variant | C/S | 7 | 1 | 0 | 980 | probably damaging | 0.979 | 28001 | likely benign | 28 |
1119 | CCND1 | rs773884084 | SNP | missense variant | C/G | 8 | 41 | 0.04 | 72 | benign | 0.071 | 24001 | likely benign | 24 |
1120 | CCND1 | rs1340132260 | SNP | missense variant | C/Y | 8 | 81 | 0.08 | 710 | possibly damaging | 0.709 | 25001 | likely benign | 25 |
1121 | CCND1 | rs761266790 | SNP | missense variant | V/M | 10 | 171 | 0.17 | 2 | benign | 0.001 | 23001 | likely benign | 23 |
1122 | CCND1 | rs1372181670 | SNP | missense variant | R/S | 14 | 591 | 0.59 | 174 | benign | 0.173 | 22001 | likely benign | 22 |
1123 | CCND1 | rs557545630 | SNP | missense variant | R/S | 15 | 1 | 0 | 899 | possibly damaging | 0.898 | 27001 | likely benign | 27 |
1124 | CCND1 | rs1299107729 | SNP | missense variant | A/S | 16 | 51 | 0.05 | 902 | possibly damaging | 0.901 | 25001 | likely benign | 25 |
1125 | CCND1 | rs772857967 | SNP | missense variant | P/A | 18 | 641 | 0.64 | 1 | benign | 0 | 20001 | likely benign | 20 |
1126 | CCND1 | rs772857967 | SNP | missense variant | P/S | 18 | 661 | 0.66 | 1 | benign | 0 | 21001 | likely benign | 21 |
1127 | CCND1 | rs1417631865 | SNP | missense variant | D/E | 19 | 31 | 0.03 | 949 | probably damaging | 0.948 | 25001 | likely benign | 25 |
1128 | CCND1 | rs766170770 | SNP | missense variant | N/D | 21 | 371 | 0.37 | 266 | benign | 0.265 | 23001 | likely benign | 23 |
1129 | CCND1 | rs753863475 | SNP | missense variant | L/F | 23 | 31 | 0.03 | 19 | benign | 0.018 | 23001 | likely benign | 23 |
1130 | CCND1 | rs1400812649 | SNP | missense variant | D/G | 25 | 1 | 0 | 761 | possibly damaging | 0.76 | 32001 | likely deleterious | 32 |
1131 | CCND1 | rs2220247 | SNP | missense variant | A/T | 30 | 411 | 0.41 | 4 | benign | 0.003 | 22001 | likely benign | 22 |
1132 | CCND1 | rs2220247 | SNP | missense variant | A/S | 30 | 421 | 0.42 | 12 | benign | 0.011 | 22001 | likely benign | 22 |
1133 | CCND1 | rs1415272481 | SNP | missense variant | A/D | 30 | 41 | 0.04 | 590 | possibly damaging | 0.589 | 26001 | likely benign | 26 |
1134 | CCND1 | rs746088878 | SNP | missense variant | E/K | 36 | 41 | 0.04 | 133 | benign | 0.132 | 26001 | likely benign | 26 |
1135 | CCND1 | rs1482952019 | SNP | missense variant | E/D | 36 | 401 | 0.4 | 8 | benign | 0.007 | 22001 | likely benign | 22 |
1136 | CCND1 | rs1263446681 | SNP | missense variant | T/S | 37 | 31 | 0.03 | 11 | benign | 0.01 | 23001 | likely benign | 23 |
1137 | CCND1 | rs780366497 | SNP | missense variant | C/W | 38 | 21 | 0.02 | 952 | probably damaging | 0.951 | 27001 | likely benign | 27 |
1138 | CCND1 | rs749614691 | SNP | missense variant | S/L | 41 | 131 | 0.13 | 302 | benign | 0.301 | 23001 | likely benign | 23 |
1139 | CCND1 | rs1173840555 | SNP | missense variant | F/L | 45 | 21 | 0.02 | 88 | benign | 0.087 | 24001 | likely benign | 24 |
1140 | CCND1 | rs747665638 | SNP | missense variant | K/E | 46 | 131 | 0.13 | 76 | benign | 0.075 | 23001 | likely benign | 23 |
1141 | CCND1 | rs1332727287 | SNP | missense variant | K/E | 50 | 71 | 0.07 | 26 | benign | 0.025 | 24001 | likely benign | 24 |
1142 | CCND1 | rs1565224527 | SNP | missense variant | K/N | 50 | 51 | 0.05 | 47 | benign | 0.046 | 24001 | likely benign | 24 |
1143 | CCND1 | rs772785280 | SNP | missense variant | E/D | 51 | 1001 | 1 | 4 | benign | 0.003 | 18001 | likely benign | 18 |
1144 | CCND1 | rs760341225 | SNP | missense variant | P/R | 54 | 1 | 0 | 995 | probably damaging | 0.994 | 28001 | likely benign | 28 |
1145 | CCND1 | rs765904377 | SNP | missense variant | M/L | 56 | 21 | 0.02 | 97 | benign | 0.096 | 24001 | likely benign | 24 |
1146 | CCND1 | rs748632355 | SNP | missense variant | T/N | 62 | 231 | 0.23 | 43 | benign | 0.042 | 22001 | likely benign | 22 |
1147 | CCND1 | rs748632355 | SNP | missense variant | T/I | 62 | 301 | 0.3 | 495 | possibly damaging | 0.494 | 24001 | likely benign | 24 |
1148 | CCND1 | rs1299820976 | SNP | missense variant | M/L | 64 | 41 | 0.04 | 198 | benign | 0.197 | 25001 | likely benign | 25 |
1149 | CCND1 | rs759345822 | SNP | missense variant | E/A | 66 | 1 | 0 | 933 | probably damaging | 0.932 | 34001 | likely deleterious | 34 |
1150 | CCND1 | rs759345822 | SNP | missense variant | E/G | 66 | 1 | 0 | 976 | probably damaging | 0.975 | 35001 | likely deleterious | 35 |
1151 | CCND1 | rs1565224976 | SNP | missense variant | V/I | 67 | 21 | 0.02 | 689 | possibly damaging | 0.688 | 33001 | likely deleterious | 33 |
1152 | CCND1 | rs769045064 | SNP | missense variant | E/G | 69 | 1 | 0 | 98 | benign | 0.097 | 29001 | likely benign | 29 |
1153 | CCND1 | rs1381472659 | SNP | missense variant | E/K | 74 | 11 | 0.01 | 148 | benign | 0.147 | 27001 | likely benign | 27 |
1154 | CCND1 | rs1171564865 | SNP | missense variant | E/K | 75 | 11 | 0.01 | 136 | benign | 0.135 | 27001 | likely benign | 27 |
1155 | CCND1 | rs778080996 | SNP | missense variant | E/K | 76 | 11 | 0.01 | 256 | benign | 0.255 | 27001 | likely benign | 27 |
1156 | CCND1 | rs746530862 | SNP | missense variant | E/D | 76 | 231 | 0.23 | 7 | benign | 0.006 | 19001 | likely benign | 19 |
1157 | CCND1 | rs781047821 | SNP | missense variant | P/S | 79 | 11 | 0.01 | 711 | possibly damaging | 0.71 | 27001 | likely benign | 27 |
1158 | CCND1 | rs1188165799 | SNP | missense variant | A/T | 81 | 1 | 0 | 416 | benign | 0.415 | 26001 | likely benign | 26 |
1159 | CCND1 | rs1471534715 | SNP | missense variant | M/V | 82 | 251 | 0.25 | 15 | benign | 0.014 | 20001 | likely benign | 20 |
1160 | CCND1 | rs1359042394 | SNP | missense variant | P/T | 93 | 61 | 0.06 | 35 | benign | 0.034 | 22001 | likely benign | 22 |
1161 | CCND1 | rs1359042394 | SNP | missense variant | P/S | 93 | 91 | 0.09 | 26 | benign | 0.025 | 22001 | likely benign | 22 |
1162 | CCND1 | rs1419585038 | SNP | missense variant | P/L | 93 | 11 | 0.01 | 212 | benign | 0.211 | 25001 | likely benign | 25 |
1163 | CCND1 | rs774091629 | SNP | missense variant | V/L | 94 | 431 | 0.43 | 8 | benign | 0.007 | 19001 | likely benign | 19 |
1164 | CCND1 | rs760878237 | SNP | missense variant | K/N | 95 | 81 | 0.08 | 59 | benign | 0.058 | 20001 | likely benign | 20 |
1165 | CCND1 | rs148113872 | SNP | missense variant | K/N | 96 | 1 | 0 | 992 | probably damaging | 0.991 | 31001 | likely deleterious | 31 |
1166 | CCND1 | rs148113872 | SNP | missense variant | K/N | 96 | 1 | 0 | 992 | probably damaging | 0.991 | 31001 | likely deleterious | 31 |
1167 | CCND1 | rs140967247 | SNP | missense variant | R/S | 98 | 341 | 0.34 | 102 | benign | 0.101 | 23001 | likely benign | 23 |
1168 | CCND1 | rs1480433568 | SNP | missense variant | L/R | 101 | 1 | 0 | 960 | probably damaging | 0.959 | 32001 | likely deleterious | 32 |
1169 | CCND1 | rs753115532 | SNP | missense variant | A/T | 104 | 111 | 0.11 | 409 | benign | 0.408 | 24001 | likely benign | 24 |
1170 | CCND1 | rs753115532 | SNP | missense variant | A/S | 104 | 231 | 0.23 | 481 | possibly damaging | 0.48 | 25001 | likely benign | 25 |
1171 | CCND1 | rs764727750 | SNP | missense variant | M/L | 107 | 321 | 0.32 | 20 | benign | 0.019 | 23001 | likely benign | 23 |
1172 | CCND1 | rs751995000 | SNP | missense variant | F/L | 108 | 341 | 0.34 | 50 | benign | 0.049 | 22001 | likely benign | 22 |
1173 | CCND1 | rs374998781 | SNP | missense variant | K/R | 114 | 521 | 0.52 | 36 | benign | 0.035 | 22001 | likely benign | 22 |
1174 | CCND1 | rs755854763 | SNP | missense variant | I/N | 117 | 441 | 0.44 | 58 | benign | 0.057 | 23001 | likely benign | 23 |
1175 | CCND1 | rs1176401077 | SNP | missense variant | I/M | 117 | 271 | 0.27 | 101 | benign | 0.1 | 18001 | likely benign | 18 |
1176 | CCND1 | rs1469991905 | SNP | missense variant | A/T | 121 | 51 | 0.05 | 496 | possibly damaging | 0.495 | 25001 | likely benign | 25 |
1177 | CCND1 | rs768334579 | SNP | missense variant | E/K | 122 | 21 | 0.02 | 382 | benign | 0.381 | 26001 | likely benign | 26 |
1178 | CCND1 | rs1373598994 | SNP | missense variant | E/G | 122 | 1 | 0 | 313 | benign | 0.312 | 26001 | likely benign | 26 |
1179 | CCND1 | rs1449765247 | SNP | missense variant | K/Q | 123 | 61 | 0.06 | 490 | possibly damaging | 0.489 | 25001 | likely benign | 25 |
1180 | CCND1 | rs774409065 | SNP | missense variant | K/M | 123 | 1 | 0 | 655 | possibly damaging | 0.654 | 31001 | likely deleterious | 31 |
1181 | CCND1 | rs748059951 | SNP | missense variant | L/P | 124 | 1 | 0 | 1001 | probably damaging | 1 | 32001 | likely deleterious | 32 |
1182 | CCND1 | rs1565225031 | SNP | missense variant | C/R | 125 | 1 | 0 | 996 | probably damaging | 0.995 | 31001 | likely deleterious | 31 |
1183 | CCND1 | rs1329584649 | SNP | missense variant | I/L | 126 | 41 | 0.04 | 26 | benign | 0.025 | 24001 | likely benign | 24 |
1184 | CCND1 | rs1375845153 | SNP | missense variant | Y/H | 127 | 1 | 0 | 974 | probably damaging | 0.973 | 32001 | likely deleterious | 32 |
1185 | CCND1 | rs1312761797 | SNP | missense variant | T/A | 128 | 21 | 0.02 | 374 | benign | 0.373 | 25001 | likely benign | 25 |
1186 | CCND1 | rs771952150 | SNP | missense variant | D/N | 129 | 11 | 0.01 | 509 | possibly damaging | 0.508 | 32001 | likely deleterious | 32 |
1187 | CCND1 | rs1050971 | SNP | missense variant | N/D | 130 | 11 | 0.01 | 215 | benign | 0.214 | 24001 | likely benign | 24 |
1188 | CCND1 | rs1050971 | SNP | missense variant | N/Y | 130 | 81 | 0.08 | 84 | benign | 0.083 | 23001 | likely benign | 23 |
1189 | CCND1 | rs1131439 | SNP | missense variant | N/S | 130 | 81 | 0.08 | 56 | benign | 0.055 | 23001 | likely benign | 23 |
1190 | CCND1 | rs759551813 | SNP | missense variant | S/F | 131 | 1 | 0 | 836 | possibly damaging | 0.835 | 29001 | likely benign | 29 |
1191 | CCND1 | rs866931401 | SNP | missense variant | R/Q | 133 | 401 | 0.4 | 1 | benign | 0 | 19001 | likely benign | 19 |
1192 | CCND1 | rs866931401 | SNP | missense variant | R/L | 133 | 211 | 0.21 | 1 | benign | 0 | 20001 | likely benign | 20 |
1193 | CCND1 | rs765498502 | SNP | missense variant | P/S | 134 | 161 | 0.16 | 55 | benign | 0.054 | 23001 | likely benign | 23 |
1194 | CCND1 | rs763443319 | SNP | missense variant | E/K | 135 | 461 | 0.46 | 4 | benign | 0.003 | 23001 | likely benign | 23 |
1195 | CCND1 | rs764335132 | SNP | missense variant | E/V | 135 | 101 | 0.1 | 15 | benign | 0.014 | 23001 | likely benign | 23 |
1196 | CCND1 | rs1184664065 | SNP | missense variant | E/A | 136 | 11 | 0.01 | 433 | benign | 0.432 | 27001 | likely benign | 27 |
1197 | CCND1 | rs900779300 | SNP | missense variant | E/D | 136 | 161 | 0.16 | 16 | benign | 0.015 | 22001 | likely benign | 22 |
1198 | CCND1 | rs752157015 | SNP | missense variant | L/M | 137 | 41 | 0.04 | 904 | possibly damaging | 0.903 | 24001 | likely benign | 24 |
1199 | CCND1 | rs1268871232 | SNP | missense variant | Q/H | 139 | 31 | 0.03 | 4 | benign | 0.003 | 23001 | likely benign | 23 |
1200 | CCND1 | rs1260695584 | SNP | missense variant | L/F | 143 | 71 | 0.07 | 332 | benign | 0.331 | 21001 | likely benign | 21 |
1201 | CCND1 | rs766855822 | SNP | missense variant | L/P | 143 | 11 | 0.01 | 396 | benign | 0.395 | 28001 | likely benign | 28 |
1202 | CCND1 | rs753296773 | SNP | missense variant | L/V | 144 | 1001 | 1 | 1 | benign | 0 | 16001 | likely benign | 16 |
1203 | CCND1 | rs374420164 | SNP | missense variant | L/F | 148 | 1 | 0 | 1000 | probably damaging | 0.999 | 27001 | likely benign | 27 |
1204 | CCND1 | rs1203615889 | SNP | missense variant | L/M | 152 | 91 | 0.09 | 921 | probably damaging | 0.92 | 22001 | likely benign | 22 |
1205 | CCND1 | rs752345237 | SNP | missense variant | A/P | 154 | 1 | 0 | 824 | possibly damaging | 0.823 | 24001 | likely benign | 24 |
1206 | CCND1 | rs752345237 | SNP | missense variant | A/S | 154 | 421 | 0.42 | 95 | benign | 0.094 | 17001 | likely benign | 17 |
1207 | CCND1 | rs1292226646 | SNP | missense variant | M/V | 155 | 1001 | 1 | 1 | benign | 0 | 11001 | likely benign | 11 |
1208 | CCND1 | rs1565225289 | SNP | missense variant | T/I | 156 | 411 | 0.41 | 991 | probably damaging | 0.99 | 23001 | likely benign | 23 |
1209 | CCND1 | rs1565225292 | SNP | missense variant | H/Y | 158 | 191 | 0.19 | 13 | benign | 0.012 | 22001 | likely benign | 22 |
1210 | CCND1 | rs11263523 | SNP | missense variant | H/Q | 158 | 111 | 0.11 | 44 | benign | 0.043 | 18001 | likely benign | 18 |
1211 | CCND1 | rs11263523 | SNP | missense variant | H/Q | 158 | 111 | 0.11 | 44 | benign | 0.043 | 18001 | likely benign | 18 |
1212 | CCND1 | rs781118003 | SNP | missense variant | D/N | 159 | 1 | 0 | 874 | possibly damaging | 0.873 | 32001 | likely deleterious | 32 |
1213 | CCND1 | rs749340325 | SNP | missense variant | D/G | 159 | 21 | 0.02 | 913 | probably damaging | 0.912 | 32001 | likely deleterious | 32 |
1214 | CCND1 | rs1447014281 | SNP | missense variant | I/M | 161 | 11 | 0.01 | 652 | possibly damaging | 0.651 | 23001 | likely benign | 23 |
1215 | CCND1 | rs1332977808 | SNP | missense variant | E/G | 162 | 31 | 0.03 | 108 | benign | 0.107 | 26001 | likely benign | 26 |
1216 | CCND1 | rs768767169 | SNP | missense variant | H/R | 163 | 11 | 0.01 | 512 | possibly damaging | 0.511 | 26001 | likely benign | 26 |
1217 | CCND1 | rs537363548 | SNP | missense variant | F/L | 164 | 101 | 0.1 | 62 | benign | 0.061 | 23001 | likely benign | 23 |
1218 | CCND1 | rs1432185835 | SNP | missense variant | L/V | 165 | 71 | 0.07 | 462 | possibly damaging | 0.461 | 24001 | likely benign | 24 |
1219 | CCND1 | rs1261290754 | SNP | missense variant | P/S | 169 | 141 | 0.14 | 92 | benign | 0.091 | 23001 | likely benign | 23 |
1220 | CCND1 | rs548963461 | SNP | missense variant | E/V | 170 | 341 | 0.34 | 1 | benign | 0 | 23001 | likely benign | 23 |
1221 | CCND1 | rs747336419 | SNP | missense variant | E/D | 170 | 81 | 0.08 | 1 | benign | 0 | 22001 | likely benign | 22 |
1222 | CCND1 | rs1565225324 | SNP | missense variant | A/P | 171 | 1001 | 1 | 1 | benign | 0 | 19001 | likely benign | 19 |
1223 | CCND1 | rs1373641771 | SNP | missense variant | A/V | 171 | 161 | 0.16 | 2 | benign | 0.001 | 22001 | likely benign | 22 |
1224 | CCND1 | rs374062310 | SNP | missense variant | N/K | 174 | 1001 | 1 | 16 | benign | 0.015 | 19001 | likely benign | 19 |
1225 | CCND1 | rs1175448240 | SNP | missense variant | K/E | 175 | 981 | 0.98 | 26 | benign | 0.025 | 22001 | likely benign | 22 |
1226 | CCND1 | rs777185874 | SNP | missense variant | Q/E | 176 | 1001 | 1 | 4 | benign | 0.003 | 19001 | likely benign | 19 |
1227 | CCND1 | rs1433903280 | SNP | missense variant | Q/L | 176 | 311 | 0.31 | 2 | benign | 0.001 | 23001 | likely benign | 23 |
1228 | CCND1 | rs143479406 | SNP | missense variant | R/H | 179 | 11 | 0.01 | 836 | possibly damaging | 0.835 | 33001 | likely deleterious | 33 |
1229 | CCND1 | rs143479406 | SNP | missense variant | R/L | 179 | 41 | 0.04 | 937 | probably damaging | 0.936 | 32001 | likely deleterious | 32 |
1230 | CCND1 | rs1176469241 | SNP | missense variant | H/Q | 181 | 1 | 0 | 871 | possibly damaging | 0.87 | 23001 | likely benign | 23 |
1231 | CCND1 | rs1434771092 | SNP | missense variant | Q/K | 183 | 21 | 0.02 | 663 | possibly damaging | 0.662 | 26001 | likely benign | 26 |
1232 | CCND1 | rs1173908293 | SNP | missense variant | T/S | 184 | 71 | 0.07 | 290 | benign | 0.289 | 22001 | likely benign | 22 |
1233 | CCND1 | rs763697017 | SNP | missense variant | V/I | 186 | 1001 | 1 | 24 | benign | 0.023 | 22001 | likely benign | 22 |
1234 | CCND1 | rs1252289930 | SNP | missense variant | A/V | 187 | 11 | 0.01 | 598 | possibly damaging | 0.597 | 28001 | likely benign | 28 |
1235 | CCND1 | rs751315372 | SNP | missense variant | L/F | 188 | 1 | 0 | 622 | possibly damaging | 0.621 | 26001 | likely benign | 26 |
1236 | CCND1 | rs757229078 | SNP | missense variant | C/Y | 189 | 1 | 0 | 998 | probably damaging | 0.997 | 32001 | likely deleterious | 32 |
1237 | CCND1 | rs534553548 | SNP | missense variant | A/S | 190 | 41 | 0.04 | 602 | possibly damaging | 0.601 | 29001 | likely benign | 29 |
1238 | CCND1 | rs201012923 | SNP | missense variant | V/M | 193 | 181 | 0.18 | 45 | benign | 0.044 | 22001 | likely benign | 22 |
1239 | CCND1 | rs1282637304 | SNP | missense variant | K/N | 194 | 331 | 0.33 | 152 | benign | 0.151 | 21001 | likely benign | 21 |
1240 | CCND1 | rs759570740 | SNP | missense variant | N/S | 198 | 351 | 0.35 | 4 | benign | 0.003 | 20001 | likely benign | 20 |
1241 | CCND1 | rs1222442441 | SNP | missense variant | P/L | 199 | 31 | 0.03 | 831 | possibly damaging | 0.83 | 26001 | likely benign | 26 |
1242 | CCND1 | rs1353308163 | SNP | missense variant | P/S | 200 | 1 | 0 | 992 | probably damaging | 0.991 | 25001 | likely benign | 25 |
1243 | CCND1 | rs893823618 | SNP | missense variant | V/L | 203 | 41 | 0.04 | 13 | benign | 0.012 | 23001 | likely benign | 23 |
1244 | CCND1 | rs751664590 | SNP | missense variant | A/T | 204 | 1 | 0 | 985 | probably damaging | 0.984 | 26001 | likely benign | 26 |
1245 | CCND1 | rs1193747086 | SNP | missense variant | A/S | 205 | 151 | 0.15 | 785 | possibly damaging | 0.784 | 23001 | likely benign | 23 |
1246 | CCND1 | rs1271260640 | SNP | missense variant | A/V | 205 | 11 | 0.01 | 859 | possibly damaging | 0.858 | 25001 | likely benign | 25 |
1247 | CCND1 | rs1011426441 | SNP | missense variant | V/M | 208 | 121 | 0.12 | 478 | possibly damaging | 0.477 | 23001 | likely benign | 23 |
1248 | CCND1 | rs750639632 | SNP | missense variant | V/A | 209 | 1001 | 1 | 2 | benign | 0.001 | 18001 | likely benign | 18 |
1249 | CCND1 | rs756509430 | SNP | missense variant | A/T | 211 | 1 | 0 | 996 | probably damaging | 0.995 | 29001 | likely benign | 29 |
1250 | CCND1 | rs112525097 | SNP | missense variant | N/K | 216 | 671 | 0.67 | 10 | benign | 0.009 | 17001 | likely benign | 17 |
1251 | CCND1 | rs149457002 | SNP | missense variant | S/N | 219 | 371 | 0.37 | 2 | benign | 0.001 | 18001 | likely benign | 18 |
1252 | CCND1 | rs1404273153 | SNP | missense variant | P/S | 220 | 971 | 0.97 | 1 | benign | 0 | 2001 | likely benign | 2 |
1253 | CCND1 | rs747703578 | SNP | missense variant | P/L | 220 | 391 | 0.39 | 1 | benign | 0 | 20001 | likely benign | 20 |
1254 | CCND1 | rs1412188214 | SNP | missense variant | N/H | 221 | 81 | 0.08 | 237 | benign | 0.236 | 20001 | likely benign | 20 |
1255 | CCND1 | rs746640562 | SNP | missense variant | L/M | 224 | 161 | 0.16 | 44 | benign | 0.043 | 22001 | likely benign | 22 |
1256 | CCND1 | rs776600964 | SNP | missense variant | Y/C | 226 | 181 | 0.18 | 1 | benign | 0 | 21001 | likely benign | 21 |
1257 | CCND1 | rs776600964 | SNP | missense variant | Y/F | 226 | 691 | 0.69 | 8 | benign | 0.007 | 16001 | likely benign | 16 |
1258 | CCND1 | rs1222446202 | SNP | missense variant | R/C | 228 | 71 | 0.07 | 13 | benign | 0.012 | 22001 | likely benign | 22 |
1259 | CCND1 | rs200179137 | SNP | missense variant | R/H | 228 | 141 | 0.14 | 2 | benign | 0.001 | 23001 | likely benign | 23 |
1260 | CCND1 | rs984643266 | SNP | missense variant | T/K | 230 | 11 | 0.01 | 914 | probably damaging | 0.913 | 26001 | likely benign | 26 |
1261 | CCND1 | rs984643266 | SNP | missense variant | T/I | 230 | 271 | 0.27 | 292 | benign | 0.291 | 22001 | likely benign | 22 |
1262 | CCND1 | rs745779714 | SNP | missense variant | R/S | 231 | 231 | 0.23 | 8 | benign | 0.007 | 16001 | likely benign | 16 |
1263 | CCND1 | rs745779714 | SNP | missense variant | R/G | 231 | 161 | 0.16 | 4 | benign | 0.003 | 17001 | likely benign | 17 |
1264 | CCND1 | rs745779714 | SNP | missense variant | R/C | 231 | 71 | 0.07 | 578 | possibly damaging | 0.577 | 23001 | likely benign | 23 |
1265 | CCND1 | rs1228811654 | SNP | missense variant | L/I | 233 | 31 | 0.03 | 961 | probably damaging | 0.96 | 26001 | likely benign | 26 |
1266 | CCND1 | rs1165177408 | SNP | missense variant | S/T | 234 | 201 | 0.2 | 12 | benign | 0.011 | 22001 | likely benign | 22 |
1267 | CCND1 | rs773470948 | SNP | missense variant | I/M | 237 | 41 | 0.04 | 946 | probably damaging | 0.945 | 23001 | likely benign | 23 |
1268 | CCND1 | rs1423874357 | SNP | missense variant | K/Q | 238 | 441 | 0.44 | 2 | benign | 0.001 | 22001 | likely benign | 22 |
1269 | CCND1 | rs760907398 | SNP | missense variant | K/N | 238 | 831 | 0.83 | 2 | benign | 0.001 | 20001 | likely benign | 20 |
1270 | CCND1 | rs777225097 | SNP | missense variant | P/L | 241 | 381 | 0.38 | 4 | benign | 0.003 | 24001 | likely benign | 24 |
1271 | CCND1 | rs913470506 | SNP | missense variant | R/W | 245 | 1 | 0 | 974 | probably damaging | 0.973 | 31001 | likely deleterious | 31 |
1272 | CCND1 | rs1565073727 | SNP | missense variant | R/Q | 245 | 91 | 0.09 | 73 | benign | 0.072 | 24001 | likely benign | 24 |
1273 | CCND1 | rs925960764 | SNP | missense variant | A/S | 246 | 171 | 0.17 | 53 | benign | 0.052 | 22001 | likely benign | 22 |
1274 | CCND1 | rs1417190579 | SNP | missense variant | C/Y | 247 | 1 | 0 | 997 | probably damaging | 0.996 | 32001 | likely deleterious | 32 |
1275 | CCND1 | rs1417190579 | SNP | missense variant | C/F | 247 | 1 | 0 | 1000 | probably damaging | 0.999 | 32001 | likely deleterious | 32 |
1276 | CCND1 | rs1446903472 | SNP | missense variant | Q/K | 250 | 21 | 0.02 | 676 | possibly damaging | 0.675 | 25001 | likely benign | 25 |
1277 | CCND1 | rs1377678585 | SNP | missense variant | Q/R | 250 | 31 | 0.03 | 637 | possibly damaging | 0.636 | 26001 | likely benign | 26 |
1278 | CCND1 | rs1173812710 | SNP | missense variant | E/K | 252 | 1 | 0 | 992 | probably damaging | 0.991 | 32001 | likely deleterious | 32 |
1279 | CCND1 | rs750012493 | SNP | missense variant | S/T | 258 | 1 | 0 | 169 | benign | 0.168 | 24001 | likely benign | 24 |
1280 | CCND1 | rs755986542 | SNP | missense variant | R/C | 260 | 31 | 0.03 | 219 | benign | 0.218 | 25001 | likely benign | 25 |
1281 | CCND1 | rs779733976 | SNP | missense variant | R/H | 260 | 21 | 0.02 | 895 | possibly damaging | 0.894 | 31001 | likely deleterious | 31 |
1282 | CCND1 | rs749069429 | SNP | missense variant | Q/P | 261 | 41 | 0.04 | 52 | benign | 0.051 | 24001 | likely benign | 24 |
1283 | CCND1 | rs749069429 | SNP | missense variant | Q/R | 261 | 51 | 0.05 | 61 | benign | 0.06 | 24001 | likely benign | 24 |
1284 | CCND1 | rs1306960346 | SNP | missense variant | Q/E | 263 | 181 | 0.18 | 24 | benign | 0.023 | 21001 | likely benign | 21 |
1285 | CCND1 | rs768582800 | SNP | missense variant | Q/K | 264 | 71 | 0.07 | 45 | benign | 0.044 | 22001 | likely benign | 22 |
1286 | CCND1 | rs1225491115 | SNP | missense variant | M/T | 266 | 431 | 0.43 | 1 | benign | 0 | 13001 | likely benign | 13 |
1287 | CCND1 | rs377271027 | SNP | missense variant | D/G | 267 | 461 | 0.46 | 1 | benign | 0 | 21001 | likely benign | 21 |
1288 | CCND1 | rs1323012735 | SNP | missense variant | P/T | 268 | 81 | 0.08 | 66 | benign | 0.065 | 19001 | likely benign | 19 |
1289 | CCND1 | rs1252799046 | SNP | missense variant | A/T | 270 | 431 | 0.43 | 106 | benign | 0.105 | 20001 | likely benign | 20 |
1290 | CCND1 | rs770991095 | SNP | missense variant | A/V | 270 | 291 | 0.29 | 61 | benign | 0.06 | 17001 | likely benign | 17 |
1291 | CCND1 | rs759765773 | SNP | missense variant | A/T | 271 | 591 | 0.59 | 2 | benign | 0.001 | 4001 | likely benign | 4 |
1292 | CCND1 | rs759765773 | SNP | missense variant | A/S | 271 | 851 | 0.85 | 2 | benign | 0.001 | 1001 | likely benign | 1 |
1293 | CCND1 | rs770021448 | SNP | missense variant | A/D | 271 | 551 | 0.55 | 4 | benign | 0.003 | 14001 | likely benign | 14 |
1294 | CCND1 | rs775723921 | SNP | missense variant | E/K | 272 | 711 | 0.71 | 10 | benign | 0.009 | 22001 | likely benign | 22 |
1295 | CCND1 | rs764757265 | SNP | missense variant | E/V | 274 | 221 | 0.22 | 8 | benign | 0.007 | 22001 | likely benign | 22 |
1296 | CCND1 | rs752108957 | SNP | missense variant | E/Q | 275 | 451 | 0.45 | 28 | benign | 0.027 | 16001 | likely benign | 16 |
1297 | CCND1 | rs1436128793 | SNP | missense variant | E/V | 276 | 241 | 0.24 | 103 | benign | 0.102 | 22001 | likely benign | 22 |
1298 | CCND1 | rs200912411 | SNP | missense variant | E/A | 279 | 371 | 0.37 | 8 | benign | 0.007 | 21001 | likely benign | 21 |
1299 | CCND1 | rs749899296 | SNP | missense variant | D/G | 282 | 71 | 0.07 | 2 | benign | 0.001 | 23001 | likely benign | 23 |
1300 | CCND1 | rs749899296 | SNP | missense variant | D/V | 282 | 11 | 0.01 | 452 | possibly damaging | 0.451 | 25001 | likely benign | 25 |
1301 | CCND1 | rs755753468 | SNP | missense variant | L/V | 283 | 511 | 0.51 | 69 | benign | 0.068 | 18001 | likely benign | 18 |
1302 | CCND1 | rs754752470 | SNP | missense variant | C/S | 285 | 1001 | 1 | 2 | benign | 0.001 | 21001 | likely benign | 21 |
1303 | CCND1 | rs1168483993 | SNP | missense variant | C/F | 285 | 201 | 0.2 | 82 | benign | 0.081 | 23001 | likely benign | 23 |
1304 | CCND1 | rs771951669 | SNP | missense variant | D/N | 289 | 1 | 0 | 998 | probably damaging | 0.997 | 32001 | likely deleterious | 32 |
1305 | CCND1 | rs781165229 | SNP | missense variant | D/E | 289 | 21 | 0.02 | 999 | probably damaging | 0.998 | 23001 | likely benign | 23 |
1306 | CCND1 | rs769921935 | SNP | missense variant | V/M | 290 | 1 | 0 | 932 | probably damaging | 0.931 | 29001 | likely benign | 29 |
1307 | CCND1 | rs769921935 | SNP | missense variant | V/L | 290 | 21 | 0.02 | 902 | possibly damaging | 0.901 | 28001 | likely benign | 28 |
1308 | CCND1 | rs1292246537 | SNP | missense variant | R/W | 291 | 1 | 0 | 973 | probably damaging | 0.972 | 30001 | likely deleterious | 30 |
1309 | CCND1 | rs775768459 | SNP | missense variant | R/Q | 291 | 211 | 0.21 | 66 | benign | 0.065 | 23001 | likely benign | 23 |
1310 | CCND1 | rs775768459 | SNP | missense variant | R/L | 291 | 51 | 0.05 | 135 | benign | 0.134 | 24001 | likely benign | 24 |
1311 | CCND1 | rs535957987 | SNP | missense variant | D/E | 292 | 81 | 0.08 | 902 | possibly damaging | 0.901 | 8001 | likely benign | 8 |
1312 | CCND1 | rs1225090625 | SNP | missense variant | V/M | 293 | 1 | 0 | 909 | possibly damaging | 0.908 | 27001 | likely benign | 27 |
1313 | PTEN | rs1554900620 | SNP | missense variant | L/P | 2 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
1314 | PTEN | rs1564837944 | SNP | missense variant | H/R | 5 | 461 | 0.46 | 1001 | probably damaging | 1 | 21001 | likely benign | 21 |
1315 | PTEN | rs1554900629 | SNP | missense variant | K/Q | 6 | 91 | 0.09 | 1001 | probably damaging | 1 | 24001 | likely benign | 24 |
1316 | PTEN | rs1554900633 | SNP | missense variant | M/V | 7 | 171 | 0.17 | 128 | benign | 0.127 | 22001 | likely benign | 22 |
1317 | PTEN | rs1554900635 | SNP | missense variant | M/K | 7 | 1 | 0 | 792 | possibly damaging | 0.791 | 24001 | likely benign | 24 |
1318 | PTEN | rs747072478 | SNP | missense variant | M/I | 7 | 1001 | 1 | 19 | benign | 0.018 | 22001 | likely benign | 22 |
1319 | PTEN | rs1434191423 | SNP | missense variant | M/V | 8 | 761 | 0.76 | 1 | benign | 0 | 21001 | likely benign | 21 |
1320 | PTEN | rs1434191423 | SNP | missense variant | M/L | 8 | 771 | 0.77 | 1 | benign | 0 | 22001 | likely benign | 22 |
1321 | PTEN | rs587781538 | SNP | missense variant | M/K | 8 | 481 | 0.48 | 38 | benign | 0.037 | 19001 | likely benign | 19 |
1322 | PTEN | rs587781538 | SNP | missense variant | M/T | 8 | 501 | 0.5 | 63 | benign | 0.062 | 20001 | likely benign | 20 |
1323 | PTEN | rs587782473 | SNP | missense variant | F/V | 9 | 21 | 0.02 | 904 | possibly damaging | 0.903 | 24001 | likely benign | 24 |
1324 | PTEN | rs786204867 | SNP | missense variant | F/S | 9 | 1 | 0 | 990 | probably damaging | 0.989 | 29001 | likely benign | 29 |
1325 | PTEN | rs786204944 | SNP | missense variant | T/S | 11 | 81 | 0.08 | 874 | possibly damaging | 0.873 | 22001 | likely benign | 22 |
1326 | PTEN | rs1085308053 | SNP | missense variant | T/I | 11 | 11 | 0.01 | 998 | probably damaging | 0.997 | 24001 | likely benign | 24 |
1327 | PTEN | rs1564837997 | SNP | missense variant | I/V | 12 | 651 | 0.65 | 8 | benign | 0.007 | 17001 | likely benign | 17 |
1328 | PTEN | rs786204868 | SNP | missense variant | P/A | 13 | 11 | 0.01 | 962 | probably damaging | 0.961 | 24001 | likely benign | 24 |
1329 | PTEN | rs786204868 | SNP | missense variant | P/S | 13 | 1 | 0 | 977 | probably damaging | 0.976 | 26001 | likely benign | 26 |
1330 | PTEN | rs776763121 | SNP | missense variant | M/V | 14 | 511 | 0.51 | 738 | possibly damaging | 0.737 | 20001 | likely benign | 20 |
1331 | PTEN | rs1185592373 | SNP | missense variant | M/T | 14 | 281 | 0.28 | 812 | possibly damaging | 0.811 | 21001 | likely benign | 21 |
1332 | PTEN | rs1554900653 | SNP | missense variant | M/I | 14 | 441 | 0.44 | 864 | possibly damaging | 0.863 | 22001 | likely benign | 22 |
1333 | PTEN | rs765433422 | SNP | missense variant | G/R | 18 | 51 | 0.05 | 169 | benign | 0.168 | 25001 | likely benign | 25 |
1334 | PTEN | rs1554900663 | SNP | missense variant | T/A | 19 | 21 | 0.02 | 486 | possibly damaging | 0.485 | 24001 | likely benign | 24 |
1335 | PTEN | rs121909232 | SNP | missense variant | C/W | 20 | 1 | 0 | 973 | probably damaging | 0.972 | 33001 | likely deleterious | 33 |
1336 | PTEN | rs1554825156 | SNP | missense variant | N/S | 21 | 801 | 0.8 | 198 | benign | 0.197 | 23001 | likely benign | 23 |
1337 | PTEN | rs1156887945 | SNP | missense variant | P/H | 22 | 1 | 0 | 995 | probably damaging | 0.994 | 26001 | likely benign | 26 |
1338 | PTEN | rs1564566726 | SNP | missense variant | Q/P | 23 | 201 | 0.2 | 603 | possibly damaging | 0.602 | 24001 | likely benign | 24 |
1339 | PTEN | rs121909234 | SNP | missense variant | V/I | 26 | 471 | 0.47 | 72 | benign | 0.071 | 22001 | likely benign | 22 |
1340 | PTEN | rs1060500117 | SNP | missense variant | V/G | 26 | 1 | 0 | 961 | probably damaging | 0.96 | 31001 | likely deleterious | 31 |
1341 | PTEN | rs1554825172 | SNP | missense variant | Q/P | 28 | 1 | 0 | 1000 | probably damaging | 0.999 | 28001 | likely benign | 28 |
1342 | PTEN | rs141373793 | SNP | missense variant | L/P | 29 | 111 | 0.11 | 995 | probably damaging | 0.994 | 25001 | likely benign | 25 |
1343 | PTEN | rs1221700050 | SNP | missense variant | K/R | 30 | 11 | 0.01 | 962 | probably damaging | 0.961 | 24001 | likely benign | 24 |
1344 | PTEN | rs878853943 | SNP | missense variant | V/M | 31 | 31 | 0.03 | 669 | possibly damaging | 0.668 | 25001 | likely benign | 25 |
1345 | PTEN | rs878853943 | SNP | missense variant | V/L | 31 | 21 | 0.02 | 669 | possibly damaging | 0.668 | 25001 | likely benign | 25 |
1346 | PTEN | rs778528056 | SNP | missense variant | K/R | 32 | 101 | 0.1 | 948 | probably damaging | 0.947 | 26001 | likely benign | 26 |
1347 | PTEN | rs778528056 | SNP | missense variant | K/M | 32 | 1 | 0 | 993 | probably damaging | 0.992 | 33001 | likely deleterious | 33 |
1348 | PTEN | rs1554825177 | SNP | missense variant | I/L | 33 | 331 | 0.33 | 998 | probably damaging | 0.997 | 23001 | likely benign | 23 |
1349 | PTEN | rs786204946 | SNP | missense variant | I/M | 33 | 11 | 0.01 | 1001 | probably damaging | 1 | 22001 | likely benign | 22 |
1350 | PTEN | rs876659433 | SNP | missense variant | Y/H | 34 | 861 | 0.86 | 2 | benign | 0.001 | 22001 | likely benign | 22 |
1351 | PTEN | rs905615413 | SNP | missense variant | S/F | 36 | 1 | 0 | 829 | possibly damaging | 0.828 | 27001 | likely benign | 27 |
1352 | PTEN | rs748240670 | SNP | missense variant | N/S | 37 | 401 | 0.4 | 8 | benign | 0.007 | 8001 | likely benign | 8 |
1353 | PTEN | rs587781998 | SNP | missense variant | S/T | 38 | 661 | 0.66 | 8 | benign | 0.007 | 20001 | likely benign | 20 |
1354 | PTEN | rs1214965807 | SNP | missense variant | S/L | 38 | 611 | 0.61 | 8 | benign | 0.007 | 23001 | likely benign | 23 |
1355 | PTEN | rs1554825190 | SNP | missense variant | P/L | 40 | 751 | 0.75 | 6 | benign | 0.005 | 22001 | likely benign | 22 |
1356 | PTEN | rs770025422 | SNP | missense variant | R/Q | 42 | 21 | 0.02 | 560 | possibly damaging | 0.559 | 23001 | likely benign | 23 |
1357 | PTEN | rs786201730 | SNP | missense variant | R/G | 43 | 191 | 0.19 | 701 | possibly damaging | 0.7 | 24001 | likely benign | 24 |
1358 | PTEN | rs786201730 | SNP | missense variant | R/W | 43 | 121 | 0.12 | 140 | benign | 0.139 | 26001 | likely benign | 26 |
1359 | PTEN | rs121909235 | SNP | missense variant | R/Q | 43 | 161 | 0.16 | 756 | possibly damaging | 0.755 | 25001 | likely benign | 25 |
1360 | PTEN | rs786201758 | SNP | missense variant | M/V | 48 | 601 | 0.6 | 8 | benign | 0.007 | 21001 | likely benign | 21 |
1361 | PTEN | rs786204871 | SNP | missense variant | M/T | 48 | 291 | 0.29 | 31 | benign | 0.03 | 22001 | likely benign | 22 |
1362 | PTEN | rs786204871 | SNP | missense variant | M/R | 48 | 11 | 0.01 | 727 | possibly damaging | 0.726 | 26001 | likely benign | 26 |
1363 | PTEN | rs1554825207 | SNP | missense variant | F/L | 50 | 301 | 0.3 | 390 | benign | 0.389 | 16001 | likely benign | 16 |
1364 | PTEN | rs1554825207 | SNP | missense variant | F/V | 50 | 171 | 0.17 | 78 | benign | 0.077 | 23001 | likely benign | 23 |
1365 | PTEN | rs121909240 | SNP | missense variant | F/S | 50 | 71 | 0.07 | 112 | benign | 0.111 | 23001 | likely benign | 23 |
1366 | PTEN | rs17849090 | SNP | missense variant | F/L | 50 | 301 | 0.3 | 390 | benign | 0.389 | 16001 | likely benign | 16 |
1367 | PTEN | rs1064794675 | SNP | missense variant | P/S | 53 | 161 | 0.16 | 992 | probably damaging | 0.991 | 23001 | likely benign | 23 |
1368 | PTEN | rs1057518538 | SNP | missense variant | Q/P | 54 | 61 | 0.06 | 957 | probably damaging | 0.956 | 23001 | likely benign | 23 |
1369 | PTEN | rs587782350 | SNP | missense variant | P/L | 55 | 51 | 0.05 | 21 | benign | 0.02 | 23001 | likely benign | 23 |
1370 | PTEN | rs1057519368 | SNP | missense variant | L/S | 56 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
1371 | PTEN | rs1564566931 | SNP | missense variant | P/S | 57 | 11 | 0.01 | 1001 | probably damaging | 1 | 24001 | likely benign | 24 |
1372 | PTEN | rs759560822 | SNP | missense variant | P/R | 57 | 1 | 0 | 1001 | probably damaging | 1 | 26001 | likely benign | 26 |
1373 | PTEN | rs1114167664 | substitution | missense variant | G/V | 60 | 1 | 0 | 993 | probably damaging | 0.992 | 29001 | likely benign | 29 |
1374 | PTEN | rs1554825226 | SNP | missense variant | G/A | 60 | 11 | 0.01 | 982 | probably damaging | 0.981 | 27001 | likely benign | 27 |
1375 | PTEN | rs1554825226 | SNP | missense variant | G/V | 60 | 1 | 0 | 993 | probably damaging | 0.992 | 29001 | likely benign | 29 |
1376 | PTEN | rs121909239 | SNP | missense variant | D/G | 61 | 11 | 0.01 | 991 | probably damaging | 0.99 | 29001 | likely benign | 29 |
1377 | PTEN | rs121909239 | SNP | missense variant | D/V | 61 | 1 | 0 | 994 | probably damaging | 0.993 | 29001 | likely benign | 29 |
1378 | PTEN | rs1554825235 | SNP | missense variant | I/N | 62 | 1 | 0 | 980 | probably damaging | 0.979 | 29001 | likely benign | 29 |
1379 | PTEN | rs1114167633 | SNP | missense variant | K/T | 63 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
1380 | PTEN | rs1564566998 | SNP | missense variant | V/E | 64 | 1 | 0 | 888 | possibly damaging | 0.887 | 28001 | likely benign | 28 |
1381 | PTEN | rs1554825245 | SNP | missense variant | F/L | 66 | 51 | 0.05 | 840 | possibly damaging | 0.839 | 22001 | likely benign | 22 |
1382 | PTEN | rs1060500125 | SNP | missense variant | K/R | 69 | 41 | 0.04 | 107 | benign | 0.106 | 24001 | likely benign | 24 |
1383 | PTEN | rs760146269 | SNP | missense variant | Q/H | 70 | 161 | 0.16 | 915 | probably damaging | 0.914 | 24001 | likely benign | 24 |
1384 | PTEN | rs763784377 | SNP | missense variant | N/T | 71 | 51 | 0.05 | 544 | possibly damaging | 0.543 | 23001 | likely benign | 23 |
1385 | PTEN | rs763784377 | SNP | missense variant | N/S | 71 | 161 | 0.16 | 69 | benign | 0.068 | 22001 | likely benign | 22 |
1386 | PTEN | rs786204872 | SNP | missense variant | L/V | 74 | 231 | 0.23 | 136 | benign | 0.135 | 20001 | likely benign | 20 |
1387 | PTEN | rs1335033900 | SNP | missense variant | L/P | 74 | 161 | 0.16 | 714 | possibly damaging | 0.713 | 25001 | likely benign | 25 |
1388 | PTEN | rs1335033900 | SNP | missense variant | L/R | 74 | 271 | 0.27 | 482 | possibly damaging | 0.481 | 23001 | likely benign | 23 |
1389 | PTEN | rs1554825264 | SNP | missense variant | K/R | 76 | 151 | 0.15 | 842 | possibly damaging | 0.841 | 25001 | likely benign | 25 |
1390 | PTEN | rs1554825266 | SNP | missense variant | K/N | 76 | 1 | 0 | 926 | probably damaging | 0.925 | 35001 | likely deleterious | 35 |
1391 | PTEN | rs398123328 | SNP | missense variant | D/E | 77 | 1001 | 1 | 45 | benign | 0.044 | 12001 | likely benign | 12 |
1392 | PTEN | rs1554825502 | SNP | missense variant | M/V | 79 | 41 | 0.04 | 299 | benign | 0.298 | 22001 | likely benign | 22 |
1393 | PTEN | rs1195369834 | SNP | missense variant | M/I | 79 | 11 | 0.01 | 278 | benign | 0.277 | 23001 | likely benign | 23 |
1394 | PTEN | rs142420551 | SNP | missense variant | F/S | 80 | 1 | 0 | 981 | probably damaging | 0.98 | 32001 | likely deleterious | 32 |
1395 | PTEN | rs1114167648 | SNP | missense variant | H/P | 81 | 11 | 0.01 | 938 | probably damaging | 0.937 | 27001 | likely benign | 27 |
1396 | PTEN | rs786204875 | SNP | missense variant | W/L | 83 | 1 | 0 | 1001 | probably damaging | 1 | 32001 | likely deleterious | 32 |
1397 | PTEN | rs1410198544 | SNP | missense variant | V/I | 84 | 591 | 0.59 | 95 | benign | 0.094 | 21001 | likely benign | 21 |
1398 | PTEN | rs1564568216 | SNP | missense variant | T/A | 86 | 11 | 0.01 | 493 | possibly damaging | 0.492 | 26001 | likely benign | 26 |
1399 | PTEN | rs398123329 | SNP | missense variant | T/K | 86 | 1 | 0 | 390 | benign | 0.389 | 26001 | likely benign | 26 |
1400 | PTEN | rs398123329 | SNP | missense variant | T/R | 86 | 1 | 0 | 827 | possibly damaging | 0.826 | 25001 | likely benign | 25 |
1401 | PTEN | rs398123329 | SNP | missense variant | T/I | 86 | 31 | 0.03 | 106 | benign | 0.105 | 23001 | likely benign | 23 |
1402 | PTEN | rs867171992 | SNP | missense variant | F/L | 87 | 1 | 0 | 604 | possibly damaging | 0.603 | 24001 | likely benign | 24 |
1403 | PTEN | rs1474354667 | SNP | missense variant | I/V | 89 | 591 | 0.59 | 160 | benign | 0.159 | 18001 | likely benign | 18 |
1404 | PTEN | rs750705904 | SNP | missense variant | P/A | 90 | 351 | 0.35 | 934 | probably damaging | 0.933 | 23001 | likely benign | 23 |
1405 | PTEN | rs750705904 | SNP | missense variant | P/S | 90 | 311 | 0.31 | 934 | probably damaging | 0.933 | 23001 | likely benign | 23 |
1406 | PTEN | rs876658988 | SNP | missense variant | P/A | 92 | 411 | 0.41 | 611 | possibly damaging | 0.61 | 19001 | likely benign | 19 |
1407 | PTEN | rs876658988 | SNP | missense variant | P/S | 92 | 431 | 0.43 | 169 | benign | 0.168 | 19001 | likely benign | 19 |
1408 | PTEN | rs1564568265 | SNP | missense variant | E/K | 94 | 301 | 0.3 | 161 | benign | 0.16 | 24001 | likely benign | 24 |
1409 | PTEN | rs1554825526 | SNP | missense variant | S/P | 96 | 411 | 0.41 | 4 | benign | 0.003 | 22001 | likely benign | 22 |
1410 | PTEN | rs1554825528 | SNP | missense variant | E/K | 97 | 201 | 0.2 | 183 | benign | 0.182 | 23001 | likely benign | 23 |
1411 | PTEN | rs562015640 | SNP | missense variant | K/E | 98 | 361 | 0.36 | 60 | benign | 0.059 | 22001 | likely benign | 22 |
1412 | PTEN | rs35600253 | SNP | missense variant | V/L | 99 | 541 | 0.54 | 19 | benign | 0.018 | 21001 | likely benign | 21 |
1413 | PTEN | rs876661234 | SNP | missense variant | V/A | 99 | 281 | 0.28 | 143 | benign | 0.142 | 22001 | likely benign | 22 |
1414 | PTEN | rs1564568318 | SNP | missense variant | E/G | 100 | 141 | 0.14 | 1001 | probably damaging | 1 | 25001 | likely benign | 25 |
1415 | PTEN | rs1175543698 | SNP | missense variant | S/N | 103 | 321 | 0.32 | 463 | possibly damaging | 0.462 | 22001 | likely benign | 22 |
1416 | PTEN | rs143335584 | SNP | missense variant | S/R | 103 | 71 | 0.07 | 806 | possibly damaging | 0.805 | 23001 | likely benign | 23 |
1417 | PTEN | rs786202207 | SNP | missense variant | C/R | 105 | 371 | 0.37 | 114 | benign | 0.113 | 21001 | likely benign | 21 |
1418 | PTEN | rs1060500121 | SNP | missense variant | C/Y | 105 | 901 | 0.9 | 92 | benign | 0.091 | 19001 | likely benign | 19 |
1419 | PTEN | rs370064195 | SNP | missense variant | D/H | 106 | 161 | 0.16 | 643 | possibly damaging | 0.642 | 25001 | likely benign | 25 |
1420 | PTEN | rs370064195 | SNP | missense variant | D/Y | 106 | 11 | 0.01 | 623 | possibly damaging | 0.622 | 24001 | likely benign | 24 |
1421 | PTEN | rs371387815 | SNP | missense variant | Q/K | 107 | 661 | 0.66 | 1 | benign | 0 | 16001 | likely benign | 16 |
1422 | PTEN | rs371387815 | SNP | missense variant | Q/E | 107 | 801 | 0.8 | 40 | benign | 0.039 | 15001 | likely benign | 15 |
1423 | PTEN | rs1554825550 | SNP | missense variant | E/G | 108 | 261 | 0.26 | 31 | benign | 0.03 | 23001 | likely benign | 23 |
1424 | PTEN | rs758644748 | SNP | missense variant | D/N | 110 | 471 | 0.47 | 376 | benign | 0.375 | 22001 | likely benign | 22 |
1425 | PTEN | rs1334444415 | SNP | missense variant | S/G | 111 | 181 | 0.18 | 1 | benign | 0 | 21001 | likely benign | 21 |
1426 | PTEN | rs745638189 | SNP | missense variant | S/N | 111 | 131 | 0.13 | 8 | benign | 0.007 | 21001 | likely benign | 21 |
1427 | PTEN | rs876660906 | SNP | missense variant | S/R | 111 | 101 | 0.1 | 256 | benign | 0.255 | 17001 | likely benign | 17 |
1428 | PTEN | rs1114167660 | SNP | missense variant | I/V | 112 | 701 | 0.7 | 8 | benign | 0.007 | 18001 | likely benign | 18 |
1429 | PTEN | rs772018727 | SNP | missense variant | I/S | 112 | 561 | 0.56 | 150 | benign | 0.149 | 22001 | likely benign | 22 |
1430 | PTEN | rs775461980 | SNP | missense variant | S/G | 114 | 121 | 0.12 | 8 | benign | 0.007 | 22001 | likely benign | 22 |
1431 | PTEN | rs587780007 | SNP | missense variant | S/N | 114 | 201 | 0.2 | 20 | benign | 0.019 | 22001 | likely benign | 22 |
1432 | PTEN | rs587780007 | SNP | missense variant | S/I | 114 | 21 | 0.02 | 137 | benign | 0.136 | 24001 | likely benign | 24 |
1433 | PTEN | rs876658345 | SNP | missense variant | S/R | 114 | 111 | 0.11 | 20 | benign | 0.019 | 21001 | likely benign | 21 |
1434 | PTEN | rs786203858 | SNP | missense variant | I/V | 115 | 591 | 0.59 | 1 | benign | 0 | 19001 | likely benign | 19 |
1435 | PTEN | rs746930141 | SNP | missense variant | E/Q | 116 | 391 | 0.39 | 50 | benign | 0.049 | 22001 | likely benign | 22 |
1436 | PTEN | rs1197734477 | SNP | missense variant | E/G | 116 | 301 | 0.3 | 13 | benign | 0.012 | 22001 | likely benign | 22 |
1437 | PTEN | rs1064794436 | SNP | missense variant | R/C | 117 | 121 | 0.12 | 6 | benign | 0.005 | 23001 | likely benign | 23 |
1438 | PTEN | rs786201507 | SNP | missense variant | R/H | 117 | 161 | 0.16 | 6 | benign | 0.005 | 23001 | likely benign | 23 |
1439 | PTEN | rs1564568473 | SNP | missense variant | D/G | 119 | 111 | 0.11 | 31 | benign | 0.03 | 24001 | likely benign | 24 |
1440 | PTEN | rs878853946 | SNP | missense variant | D/N | 121 | 131 | 0.13 | 895 | possibly damaging | 0.894 | 23001 | likely benign | 23 |
1441 | PTEN | rs863224667 | SNP | missense variant | D/G | 121 | 271 | 0.27 | 161 | benign | 0.16 | 23001 | likely benign | 23 |
1442 | PTEN | rs562164491 | SNP | missense variant | K/N | 122 | 141 | 0.14 | 878 | possibly damaging | 0.877 | 18001 | likely benign | 18 |
1443 | PTEN | rs1171478249 | SNP | missense variant | E/A | 123 | 201 | 0.2 | 694 | possibly damaging | 0.693 | 23001 | likely benign | 23 |
1444 | PTEN | rs1554825577 | SNP | missense variant | L/I | 125 | 71 | 0.07 | 967 | probably damaging | 0.966 | 22001 | likely benign | 22 |
1445 | PTEN | rs1064793345 | SNP | missense variant | L/P | 125 | 11 | 0.01 | 1000 | probably damaging | 0.999 | 25001 | likely benign | 25 |
1446 | PTEN | rs876658630 | SNP | missense variant | V/I | 126 | 601 | 0.6 | 2 | benign | 0.001 | 19001 | likely benign | 19 |
1447 | PTEN | rs761350690 | SNP | missense variant | T/N | 128 | 71 | 0.07 | 482 | possibly damaging | 0.481 | 23001 | likely benign | 23 |
1448 | PTEN | rs761350690 | SNP | missense variant | T/I | 128 | 151 | 0.15 | 30 | benign | 0.029 | 23001 | likely benign | 23 |
1449 | PTEN | rs1373782343 | SNP | missense variant | D/Y | 133 | 11 | 0.01 | 968 | probably damaging | 0.967 | 29001 | likely benign | 29 |
1450 | PTEN | rs1114167654 | SNP | missense variant | L/P | 134 | 1 | 0 | 995 | probably damaging | 0.994 | 28001 | likely benign | 28 |
1451 | PTEN | rs1114167654 | SNP | missense variant | L/R | 134 | 1 | 0 | 520 | possibly damaging | 0.519 | 24001 | likely benign | 24 |
1452 | PTEN | rs1554825607 | SNP | missense variant | K/E | 139 | 1 | 0 | 858 | possibly damaging | 0.857 | 27001 | likely benign | 27 |
1453 | PTEN | rs1554825616 | SNP | missense variant | A/V | 142 | 91 | 0.09 | 953 | probably damaging | 0.952 | 24001 | likely benign | 24 |
1454 | PTEN | rs1206321984 | SNP | missense variant | N/S | 143 | 21 | 0.02 | 1000 | probably damaging | 0.999 | 25001 | likely benign | 25 |
1455 | PTEN | rs1554825620 | SNP | missense variant | N/K | 143 | 61 | 0.06 | 1000 | probably damaging | 0.999 | 22001 | likely benign | 22 |
1456 | PTEN | rs1085308040 | SNP | missense variant | R/Q | 144 | 61 | 0.06 | 264 | benign | 0.263 | 24001 | likely benign | 24 |
1457 | PTEN | rs1085308040 | SNP | missense variant | R/L | 144 | 51 | 0.05 | 873 | possibly damaging | 0.872 | 25001 | likely benign | 25 |
1458 | PTEN | rs1554825641 | SNP | missense variant | F/Y | 146 | 281 | 0.28 | 937 | probably damaging | 0.936 | 24001 | likely benign | 24 |
1459 | PTEN | rs1564568679 | SNP | missense variant | P/Q | 148 | 1 | 0 | 1001 | probably damaging | 1 | 24001 | likely benign | 24 |
1460 | PTEN | rs759852661 | SNP | missense variant | N/H | 149 | 11 | 0.01 | 1001 | probably damaging | 1 | 26001 | likely benign | 26 |
1461 | PTEN | rs759852661 | SNP | missense variant | N/D | 149 | 261 | 0.26 | 1000 | probably damaging | 0.999 | 23001 | likely benign | 23 |
1462 | PTEN | rs1554825649 | SNP | missense variant | N/K | 149 | 11 | 0.01 | 1000 | probably damaging | 0.999 | 25001 | likely benign | 25 |
1463 | PTEN | rs1554825652 | SNP | missense variant | F/V | 150 | 1 | 0 | 1000 | probably damaging | 0.999 | 28001 | likely benign | 28 |
1464 | PTEN | rs1064794080 | SNP | missense variant | K/T | 151 | 1 | 0 | 962 | probably damaging | 0.961 | 33001 | likely deleterious | 33 |
1465 | PTEN | rs398123314 | SNP | missense variant | K/N | 151 | 21 | 0.02 | 948 | probably damaging | 0.947 | 35001 | likely deleterious | 35 |
1466 | PTEN | rs786201041 | SNP | missense variant | V/I | 152 | 1 | 0 | 982 | probably damaging | 0.981 | 34001 | likely deleterious | 34 |
1467 | PTEN | rs786201041 | SNP | missense variant | V/L | 152 | 1 | 0 | 944 | probably damaging | 0.943 | 34001 | likely deleterious | 34 |
1468 | PTEN | rs1114167624 | SNP | missense variant | V/A | 152 | 1 | 0 | 986 | probably damaging | 0.985 | 32001 | likely deleterious | 32 |
1469 | PTEN | rs1114167624 | SNP | missense variant | V/G | 152 | 1 | 0 | 998 | probably damaging | 0.997 | 34001 | likely deleterious | 34 |
1470 | PTEN | rs1274425509 | SNP | missense variant | S/R | 153 | 21 | 0.02 | 19 | benign | 0.018 | 23001 | likely benign | 23 |
1471 | ERBB2 | rs1379316719 | SNP | missense variant | E/G | 2 | 11 | 0.01 | 1 | benign | 0 | 26001 | likely benign | 26 |
1472 | ERBB2 | rs1039589946 | SNP | missense variant | A/S | 4 | 141 | 0.14 | 2 | benign | 0.001 | 22001 | likely benign | 22 |
1473 | ERBB2 | rs1428243929 | SNP | missense variant | A/V | 4 | 11 | 0.01 | 52 | benign | 0.051 | 23001 | likely benign | 23 |
1474 | ERBB2 | rs1456994901 | SNP | missense variant | L/F | 11 | 301 | 0.3 | 1 | benign | 0 | 17001 | likely benign | 17 |
1475 | ERBB2 | rs1318994039 | SNP | missense variant | L/F | 12 | 71 | 0.07 | 970 | probably damaging | 0.969 | 23001 | likely benign | 23 |
1476 | ERBB2 | rs1263781765 | SNP | missense variant | L/F | 13 | 161 | 0.16 | 1 | benign | 0 | 17001 | likely benign | 17 |
1477 | ERBB2 | rs1442246817 | SNP | missense variant | A/S | 14 | 681 | 0.68 | 210 | benign | 0.209 | 17001 | likely benign | 17 |
1478 | ERBB2 | rs1293505485 | SNP | missense variant | A/V | 14 | 311 | 0.31 | 2 | benign | 0.001 | 21001 | likely benign | 21 |
1479 | ERBB2 | rs193171026 | SNP | missense variant | L/F | 15 | 81 | 0.08 | 541 | possibly damaging | 0.54 | 23001 | likely benign | 23 |
1480 | ERBB2 | rs1225599701 | SNP | missense variant | L/V | 16 | 421 | 0.42 | 900 | possibly damaging | 0.899 | 21001 | likely benign | 21 |
1481 | ERBB2 | rs1567892325 | SNP | missense variant | L/F | 16 | 221 | 0.22 | 970 | probably damaging | 0.969 | 23001 | likely benign | 23 |
1482 | ERBB2 | rs1307888184 | SNP | missense variant | P/T | 17 | 411 | 0.41 | 18 | benign | 0.017 | 15001 | likely benign | 15 |
1483 | ERBB2 | rs1307888184 | SNP | missense variant | P/S | 17 | 441 | 0.44 | 1 | benign | 0 | 15001 | likely benign | 15 |
1484 | ERBB2 | rs1184958761 | SNP | missense variant | P/S | 18 | 431 | 0.43 | 1 | benign | 0 | 17001 | likely benign | 17 |
1485 | ERBB2 | rs1486972911 | SNP | missense variant | G/R | 19 | 61 | 0.06 | 4 | benign | 0.003 | 22001 | likely benign | 22 |
1486 | ERBB2 | rs993479758 | SNP | missense variant | G/A | 19 | 281 | 0.28 | 2 | benign | 0.001 | 19001 | likely benign | 19 |
1487 | ERBB2 | rs1004896536 | SNP | missense variant | A/V | 21 | 611 | 0.61 | 30 | benign | 0.029 | 18001 | likely benign | 18 |
1488 | ERBB2 | rs896376245 | SNP | missense variant | S/N | 22 | 421 | 0.42 | 1 | benign | 0 | 19001 | likely benign | 19 |
1489 | ERBB2 | rs755921683 | SNP | missense variant | V/A | 25 | 31 | 0.03 | 75 | benign | 0.074 | 15001 | likely benign | 15 |
1490 | ERBB2 | rs779913120 | SNP | missense variant | T/P | 27 | 331 | 0.33 | 557 | possibly damaging | 0.556 | 23001 | likely benign | 23 |
1491 | ERBB2 | rs1365546088 | SNP | missense variant | T/I | 27 | 251 | 0.25 | 260 | benign | 0.259 | 20001 | likely benign | 20 |
1492 | ERBB2 | rs564064363 | SNP | missense variant | G/S | 28 | 1 | 0 | 1000 | probably damaging | 0.999 | 29001 | likely benign | 29 |
1493 | ERBB2 | rs564064363 | SNP | missense variant | G/R | 28 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
1494 | ERBB2 | rs1284110310 | SNP | missense variant | G/D | 28 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
1495 | ERBB2 | rs778487069 | SNP | missense variant | D/Y | 30 | 11 | 0.01 | 853 | possibly damaging | 0.852 | 28001 | likely benign | 28 |
1496 | ERBB2 | rs998740859 | SNP | missense variant | M/L | 31 | 51 | 0.05 | 4 | benign | 0.003 | 22001 | likely benign | 22 |
1497 | ERBB2 | rs546886845 | SNP | missense variant | M/I | 31 | 21 | 0.02 | 62 | benign | 0.061 | 24001 | likely benign | 24 |
1498 | ERBB2 | rs149937802 | SNP | missense variant | R/W | 34 | 11 | 0.01 | 467 | possibly damaging | 0.466 | 25001 | likely benign | 25 |
1499 | ERBB2 | rs921911454 | SNP | missense variant | R/Q | 34 | 311 | 0.31 | 1 | benign | 0 | 13001 | likely benign | 13 |
1500 | ERBB2 | rs777171280 | SNP | missense variant | L/P | 35 | 121 | 0.12 | 12 | benign | 0.011 | 15001 | likely benign | 15 |
1501 | ERBB2 | rs765607521 | SNP | missense variant | A/P | 37 | 101 | 0.1 | 99 | benign | 0.098 | 21001 | likely benign | 21 |
1502 | ERBB2 | rs1459247021 | SNP | missense variant | S/G | 38 | 21 | 0.02 | 807 | possibly damaging | 0.806 | 25001 | likely benign | 25 |
1503 | ERBB2 | rs1216236852 | SNP | missense variant | P/A | 39 | 501 | 0.5 | 4 | benign | 0.003 | 16001 | likely benign | 16 |
1504 | ERBB2 | rs763193414 | SNP | missense variant | E/K | 40 | 21 | 0.02 | 627 | possibly damaging | 0.626 | 26001 | likely benign | 26 |
1505 | ERBB2 | rs1311415529 | SNP | missense variant | D/V | 44 | 241 | 0.24 | 4 | benign | 0.003 | 22001 | likely benign | 22 |
1506 | ERBB2 | rs587778266 | SNP | missense variant | M/V | 45 | 81 | 0.08 | 2 | benign | 0.001 | 19001 | likely benign | 19 |
1507 | ERBB2 | rs1281942958 | SNP | missense variant | M/I | 45 | 11 | 0.01 | 2 | benign | 0.001 | 22001 | likely benign | 22 |
1508 | ERBB2 | rs764222200 | SNP | missense variant | L/P | 46 | 1 | 0 | 935 | probably damaging | 0.934 | 28001 | likely benign | 28 |
1509 | ERBB2 | rs1236052395 | SNP | missense variant | R/C | 47 | 11 | 0.01 | 438 | benign | 0.437 | 23001 | likely benign | 23 |
1510 | ERBB2 | rs144019910 | SNP | missense variant | R/H | 47 | 71 | 0.07 | 1 | benign | 0 | 22001 | likely benign | 22 |
1511 | ERBB2 | rs1187611727 | SNP | missense variant | L/F | 49 | 51 | 0.05 | 852 | possibly damaging | 0.851 | 23001 | likely benign | 23 |
1512 | ERBB2 | rs1390107974 | SNP | missense variant | Q/R | 51 | 231 | 0.23 | 1 | benign | 0 | 20001 | likely benign | 20 |
1513 | ERBB2 | rs1220384939 | SNP | missense variant | Q/H | 51 | 41 | 0.04 | 1 | benign | 0 | 21001 | likely benign | 21 |
1514 | ERBB2 | rs140441229 | SNP | missense variant | Q/R | 57 | 21 | 0.02 | 856 | possibly damaging | 0.855 | 26001 | likely benign | 26 |
1515 | ERBB2 | rs1298421770 | SNP | missense variant | G/E | 58 | 291 | 0.29 | 913 | probably damaging | 0.912 | 24001 | likely benign | 24 |
1516 | ERBB2 | rs1332501526 | SNP | missense variant | L/V | 60 | 1 | 0 | 1001 | probably damaging | 1 | 23001 | likely benign | 23 |
1517 | ERBB2 | rs766186178 | SNP | missense variant | E/Q | 61 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
1518 | ERBB2 | rs1013215187 | SNP | missense variant | L/V | 62 | 101 | 0.1 | 49 | benign | 0.048 | 21001 | likely benign | 21 |
1519 | ERBB2 | rs753655456 | SNP | missense variant | T/I | 63 | 1 | 0 | 1001 | probably damaging | 1 | 25001 | likely benign | 25 |
1520 | ERBB2 | rs1364385133 | SNP | missense variant | P/L | 66 | 281 | 0.28 | 38 | benign | 0.037 | 19001 | likely benign | 19 |
1521 | ERBB2 | rs778575008 | SNP | missense variant | T/A | 67 | 751 | 0.75 | 1 | benign | 0 | 14001 | likely benign | 14 |
1522 | ERBB2 | rs752339377 | SNP | missense variant | T/I | 67 | 151 | 0.15 | 42 | benign | 0.041 | 19001 | likely benign | 19 |
1523 | ERBB2 | rs757899978 | SNP | missense variant | N/S | 68 | 181 | 0.18 | 4 | benign | 0.003 | 15001 | likely benign | 15 |
1524 | ERBB2 | rs777347427 | SNP | missense variant | A/G | 69 | 311 | 0.31 | 183 | benign | 0.182 | 22001 | likely benign | 22 |
1525 | ERBB2 | rs61737968 | SNP | missense variant | E/A | 79 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
1526 | ERBB2 | rs376524324 | SNP | missense variant | V/M | 84 | 11 | 0.01 | 655 | possibly damaging | 0.654 | 23001 | likely benign | 23 |
1527 | ERBB2 | rs759478535 | SNP | missense variant | I/V | 86 | 401 | 0.4 | 32 | benign | 0.031 | 18001 | likely benign | 18 |
1528 | ERBB2 | rs775382058 | SNP | missense variant | A/T | 87 | 1 | 0 | 999 | probably damaging | 0.998 | 29001 | likely benign | 29 |
1529 | ERBB2 | rs1181714248 | SNP | missense variant | H/Y | 88 | 211 | 0.21 | 324 | benign | 0.323 | 19001 | likely benign | 19 |
1530 | ERBB2 | rs762638680 | SNP | missense variant | H/Q | 88 | 401 | 0.4 | 7 | benign | 0.006 | 16001 | likely benign | 16 |
1531 | ERBB2 | rs763850846 | SNP | missense variant | Q/P | 90 | 171 | 0.17 | 217 | benign | 0.216 | 9001 | likely benign | 9 |
1532 | ERBB2 | rs1368945502 | SNP | missense variant | Q/R | 93 | 391 | 0.39 | 1 | benign | 0 | 10001 | likely benign | 10 |
1533 | ERBB2 | rs767151455 | SNP | missense variant | P/L | 95 | 1 | 0 | 991 | probably damaging | 0.99 | 25001 | likely benign | 25 |
1534 | ERBB2 | rs749886389 | SNP | missense variant | R/W | 100 | 1 | 0 | 1000 | probably damaging | 0.999 | 24001 | likely benign | 24 |
1535 | ERBB2 | rs756720659 | SNP | missense variant | R/Q | 100 | 321 | 0.32 | 342 | benign | 0.341 | 23001 | likely benign | 23 |
1536 | ERBB2 | rs539140755 | SNP | missense variant | I/T | 101 | 1 | 0 | 995 | probably damaging | 0.994 | 27001 | likely benign | 27 |
1537 | ERBB2 | rs950730453 | SNP | missense variant | R/Q | 103 | 1 | 0 | 1001 | probably damaging | 1 | 31001 | likely deleterious | 31 |
1538 | ERBB2 | rs1348253156 | SNP | missense variant | T/I | 105 | 51 | 0.05 | 896 | possibly damaging | 0.895 | 23001 | likely benign | 23 |
1539 | ERBB2 | rs1395467940 | SNP | missense variant | Q/E | 106 | 671 | 0.67 | 534 | possibly damaging | 0.533 | 22001 | likely benign | 22 |
1540 | ERBB2 | rs1416951791 | SNP | missense variant | Q/H | 106 | 121 | 0.12 | 926 | probably damaging | 0.925 | 23001 | likely benign | 23 |
1541 | ERBB2 | rs749711404 | SNP | missense variant | D/G | 110 | 671 | 0.67 | 4 | benign | 0.003 | 22001 | likely benign | 22 |
1542 | ERBB2 | rs749711404 | SNP | missense variant | D/V | 110 | 11 | 0.01 | 322 | benign | 0.321 | 24001 | likely benign | 24 |
1543 | ERBB2 | rs1340287026 | SNP | missense variant | N/S | 111 | 631 | 0.63 | 1 | benign | 0 | 1 | likely benign | 0 |
1544 | ERBB2 | rs1253654469 | SNP | missense variant | Y/C | 112 | 1 | 0 | 985 | probably damaging | 0.984 | 24001 | likely benign | 24 |
1545 | ERBB2 | rs1272695341 | SNP | missense variant | A/T | 115 | 91 | 0.09 | 258 | benign | 0.257 | 23001 | likely benign | 23 |
1546 | ERBB2 | rs748301823 | SNP | missense variant | A/V | 115 | 51 | 0.05 | 36 | benign | 0.035 | 22001 | likely benign | 22 |
1547 | ERBB2 | rs1256572460 | SNP | missense variant | V/M | 116 | 1 | 0 | 993 | probably damaging | 0.992 | 27001 | likely benign | 27 |
1548 | ERBB2 | rs1423090731 | SNP | missense variant | V/A | 116 | 41 | 0.04 | 859 | possibly damaging | 0.858 | 26001 | likely benign | 26 |
1549 | ERBB2 | rs769775277 | SNP | missense variant | D/N | 121 | 501 | 0.5 | 7 | benign | 0.006 | 19001 | likely benign | 19 |
1550 | ERBB2 | rs141135746 | SNP | missense variant | P/A | 122 | 741 | 0.74 | 1 | benign | 0 | 7001 | likely benign | 7 |
1551 | ERBB2 | rs370959592 | SNP | missense variant | P/L | 122 | 351 | 0.35 | 1 | benign | 0 | 6001 | likely benign | 6 |
1552 | ERBB2 | rs1283546661 | SNP | missense variant | N/Y | 124 | 141 | 0.14 | 291 | benign | 0.29 | 17001 | likely benign | 17 |
1553 | ERBB2 | rs970583285 | SNP | missense variant | T/P | 127 | 131 | 0.13 | 13 | benign | 0.012 | 11001 | likely benign | 11 |
1554 | ERBB2 | rs761564667 | SNP | missense variant | P/A | 128 | 371 | 0.37 | 1 | benign | 0 | 1001 | likely benign | 1 |
1555 | ERBB2 | rs373824622 | SNP | missense variant | P/R | 128 | 231 | 0.23 | 125 | benign | 0.124 | 12001 | likely benign | 12 |
1556 | ERBB2 | rs766949725 | SNP | missense variant | V/F | 129 | 681 | 0.68 | 79 | benign | 0.078 | 11001 | likely benign | 11 |
1557 | ERBB2 | rs754295165 | SNP | missense variant | P/S | 134 | 781 | 0.78 | 4 | benign | 0.003 | 8001 | likely benign | 8 |
1558 | ERBB2 | rs865925114 | SNP | missense variant | P/Q | 134 | 601 | 0.6 | 4 | benign | 0.003 | 11001 | likely benign | 11 |
1559 | ERBB2 | rs755427616 | SNP | missense variant | G/S | 136 | 1 | 0 | 996 | probably damaging | 0.995 | 27001 | likely benign | 27 |
1560 | ERBB2 | rs200208742 | SNP | missense variant | L/Q | 137 | 1 | 0 | 998 | probably damaging | 0.997 | 27001 | likely benign | 27 |
1561 | ERBB2 | rs200208742 | SNP | missense variant | L/P | 137 | 1 | 0 | 1000 | probably damaging | 0.999 | 28001 | likely benign | 28 |
1562 | ERBB2 | rs200208742 | SNP | missense variant | L/R | 137 | 1 | 0 | 947 | probably damaging | 0.946 | 27001 | likely benign | 27 |
1563 | ERBB2 | rs779156384 | SNP | missense variant | R/W | 138 | 1 | 0 | 929 | probably damaging | 0.928 | 26001 | likely benign | 26 |
1564 | ERBB2 | rs748476466 | SNP | missense variant | R/Q | 138 | 191 | 0.19 | 59 | benign | 0.058 | 15001 | likely benign | 15 |
1565 | ERBB2 | rs758646541 | SNP | missense variant | E/D | 139 | 11 | 0.01 | 768 | possibly damaging | 0.767 | 24001 | likely benign | 24 |
1566 | ERBB2 | rs1304310205 | SNP | missense variant | L/V | 142 | 1 | 0 | 570 | possibly damaging | 0.569 | 28001 | likely benign | 28 |
1567 | ERBB2 | rs185670819 | SNP | missense variant | R/Q | 143 | 61 | 0.06 | 83 | benign | 0.082 | 22001 | likely benign | 22 |
1568 | ERBB2 | rs185670819 | SNP | missense variant | R/P | 143 | 11 | 0.01 | 907 | possibly damaging | 0.906 | 26001 | likely benign | 26 |
1569 | ERBB2 | rs1187893378 | SNP | missense variant | S/N | 144 | 841 | 0.84 | 4 | benign | 0.003 | 17001 | likely benign | 17 |
1570 | ERBB2 | rs527779103 | SNP | missense variant | L/F | 145 | 1 | 0 | 1000 | probably damaging | 0.999 | 26001 | likely benign | 26 |
1571 | ERBB2 | rs200963868 | SNP | missense variant | G/V | 151 | 1 | 0 | 1001 | probably damaging | 1 | 32001 | likely deleterious | 32 |
1572 | ERBB2 | rs151122410 | SNP | missense variant | G/A | 152 | 181 | 0.18 | 265 | benign | 0.264 | 22001 | likely benign | 22 |
1573 | ERBB2 | rs778041266 | SNP | missense variant | V/L | 153 | 31 | 0.03 | 507 | possibly damaging | 0.506 | 24001 | likely benign | 24 |
1574 | ERBB2 | rs757446217 | SNP | missense variant | L/F | 154 | 651 | 0.65 | 14 | benign | 0.013 | 19001 | likely benign | 19 |
1575 | ERBB2 | rs781137961 | SNP | missense variant | R/W | 157 | 21 | 0.02 | 777 | possibly damaging | 0.776 | 27001 | likely benign | 27 |
1576 | ERBB2 | rs745921471 | SNP | missense variant | R/Q | 157 | 771 | 0.77 | 13 | benign | 0.012 | 22001 | likely benign | 22 |
1577 | ERBB2 | rs768502081 | SNP | missense variant | N/K | 158 | 1 | 0 | 965 | probably damaging | 0.964 | 24001 | likely benign | 24 |
1578 | ERBB2 | rs778888794 | SNP | missense variant | P/T | 159 | 81 | 0.08 | 568 | possibly damaging | 0.567 | 22001 | likely benign | 22 |
1579 | ERBB2 | rs778888794 | SNP | missense variant | P/S | 159 | 11 | 0.01 | 887 | possibly damaging | 0.886 | 24001 | likely benign | 24 |
1580 | ERBB2 | rs1474799396 | SNP | missense variant | P/L | 159 | 31 | 0.03 | 952 | probably damaging | 0.951 | 25001 | likely benign | 25 |
1581 | ERBB2 | rs1327422858 | SNP | missense variant | Q/L | 160 | 651 | 0.65 | 100 | benign | 0.099 | 22001 | likely benign | 22 |
1582 | ERBB2 | rs774604250 | SNP | missense variant | L/V | 161 | 1 | 0 | 994 | probably damaging | 0.993 | 24001 | likely benign | 24 |
1583 | ERBB2 | rs1567899208 | SNP | missense variant | Y/C | 163 | 161 | 0.16 | 871 | possibly damaging | 0.87 | 23001 | likely benign | 23 |
1584 | ERBB2 | rs747995543 | SNP | missense variant | Q/R | 164 | 101 | 0.1 | 987 | probably damaging | 0.986 | 23001 | likely benign | 23 |
1585 | ERBB2 | rs771986239 | SNP | missense variant | D/H | 165 | 31 | 0.03 | 183 | benign | 0.182 | 24001 | likely benign | 24 |
1586 | ERBB2 | rs1227559137 | SNP | missense variant | T/M | 166 | 21 | 0.02 | 389 | benign | 0.388 | 15001 | likely benign | 15 |
1587 | ERBB2 | rs1269105876 | SNP | missense variant | K/Q | 170 | 961 | 0.96 | 1 | benign | 0 | 5001 | likely benign | 5 |
1588 | ERBB2 | rs1269105876 | SNP | missense variant | K/E | 170 | 951 | 0.95 | 1 | benign | 0 | 6001 | likely benign | 6 |
1589 | ERBB2 | rs1222267645 | SNP | missense variant | K/T | 175 | 271 | 0.27 | 10 | benign | 0.009 | 19001 | likely benign | 19 |
1590 | ERBB2 | rs1222267645 | SNP | missense variant | K/R | 175 | 191 | 0.19 | 2 | benign | 0.001 | 19001 | likely benign | 19 |
1591 | ERBB2 | rs776032539 | SNP | missense variant | N/S | 177 | 541 | 0.54 | 1 | benign | 0 | 16001 | likely benign | 16 |
1592 | ERBB2 | rs1053130436 | SNP | missense variant | Q/K | 178 | 951 | 0.95 | 1 | benign | 0 | 5001 | likely benign | 5 |
1593 | ERBB2 | rs1053130436 | SNP | missense variant | Q/E | 178 | 1001 | 1 | 1 | benign | 0 | 3001 | likely benign | 3 |
1594 | ERBB2 | rs1010848650 | SNP | missense variant | L/V | 183 | 511 | 0.51 | 1 | benign | 0 | 1 | likely benign | 0 |
1595 | ERBB2 | rs1416532705 | SNP | missense variant | T/I | 186 | 171 | 0.17 | 11 | benign | 0.01 | 7001 | likely benign | 7 |
1596 | ERBB2 | rs765706190 | SNP | missense variant | R/S | 188 | 911 | 0.91 | 13 | benign | 0.012 | 15001 | likely benign | 15 |
1597 | ERBB2 | rs765706190 | SNP | missense variant | R/C | 188 | 91 | 0.09 | 755 | possibly damaging | 0.754 | 23001 | likely benign | 23 |
1598 | ERBB2 | rs763371007 | SNP | missense variant | R/H | 188 | 391 | 0.39 | 2 | benign | 0.001 | 17001 | likely benign | 17 |
1599 | ERBB2 | rs753419830 | SNP | missense variant | R/W | 190 | 21 | 0.02 | 926 | probably damaging | 0.925 | 23001 | likely benign | 23 |
1600 | ERBB2 | rs531563820 | SNP | missense variant | R/Q | 190 | 581 | 0.58 | 433 | benign | 0.432 | 20001 | likely benign | 20 |
1601 | ERBB2 | rs531563820 | SNP | missense variant | R/P | 190 | 361 | 0.36 | 31 | benign | 0.03 | 19001 | likely benign | 19 |
1602 | ERBB2 | rs769335702 | SNP | missense variant | H/Q | 193 | 1001 | 1 | 1 | benign | 0 | 1 | likely benign | 0 |
1603 | ERBB2 | rs763458661 | SNP | missense variant | P/S | 194 | 241 | 0.24 | 16 | benign | 0.015 | 14001 | likely benign | 14 |
1604 | ERBB2 | rs764545872 | SNP | missense variant | P/L | 194 | 81 | 0.08 | 13 | benign | 0.012 | 16001 | likely benign | 16 |
1605 | ERBB2 | rs1209871684 | SNP | missense variant | C/Y | 195 | 1 | 0 | 994 | probably damaging | 0.993 | 24001 | likely benign | 24 |
1606 | ERBB2 | rs1241783659 | SNP | missense variant | S/F | 196 | 41 | 0.04 | 461 | possibly damaging | 0.46 | 22001 | likely benign | 22 |
1607 | ERBB2 | rs113619125 | SNP | missense variant | P/L | 197 | 31 | 0.03 | 128 | benign | 0.127 | 17001 | likely benign | 17 |
1608 | ERBB2 | rs1451675784 | SNP | missense variant | M/L | 198 | 201 | 0.2 | 1 | benign | 0 | 6001 | likely benign | 6 |
1609 | ERBB2 | rs908142099 | SNP | missense variant | M/T | 198 | 131 | 0.13 | 1 | benign | 0 | 2001 | likely benign | 2 |
1610 | ERBB2 | rs767673890 | SNP | missense variant | M/I | 198 | 81 | 0.08 | 1 | benign | 0 | 2001 | likely benign | 2 |
1611 | ERBB2 | rs750651941 | SNP | missense variant | G/V | 201 | 161 | 0.16 | 4 | benign | 0.003 | 1 | likely benign | 0 |
1612 | ERBB2 | rs1185455152 | SNP | missense variant | S/P | 202 | 121 | 0.12 | 1 | benign | 0 | 3001 | likely benign | 3 |
1613 | ERBB2 | rs1426154971 | SNP | missense variant | S/F | 202 | 1 | 0 | 394 | benign | 0.393 | 18001 | likely benign | 18 |
1614 | ERBB2 | rs971655376 | SNP | missense variant | R/C | 203 | 171 | 0.17 | 128 | benign | 0.127 | 11001 | likely benign | 11 |
1615 | ERBB2 | rs896171398 | SNP | missense variant | R/H | 203 | 721 | 0.72 | 1 | benign | 0 | 4001 | likely benign | 4 |
1616 | ERBB2 | rs896171398 | SNP | missense variant | R/P | 203 | 211 | 0.21 | 48 | benign | 0.047 | 9001 | likely benign | 9 |
1617 | ERBB2 | rs1265935073 | SNP | missense variant | D/Y | 211 | 191 | 0.19 | 30 | benign | 0.029 | 24001 | likely benign | 24 |
1618 | ERBB2 | rs1363819722 | SNP | missense variant | C/W | 212 | 1 | 0 | 1001 | probably damaging | 1 | 25001 | likely benign | 25 |
1619 | ERBB2 | rs753902254 | SNP | missense variant | S/I | 214 | 201 | 0.2 | 2 | benign | 0.001 | 6001 | likely benign | 6 |
1620 | ERBB2 | rs770976272 | SNP | missense variant | T/M | 216 | 1 | 0 | 1001 | probably damaging | 1 | 25001 | likely benign | 25 |
1621 | ERBB2 | rs768151310 | SNP | missense variant | R/C | 217 | 1 | 0 | 917 | probably damaging | 0.916 | 23001 | likely benign | 23 |
1622 | ERBB2 | rs779346332 | SNP | missense variant | R/H | 217 | 51 | 0.05 | 34 | benign | 0.033 | 21001 | likely benign | 21 |
1623 | ERBB2 | rs1473418882 | SNP | missense variant | T/A | 218 | 381 | 0.38 | 8 | benign | 0.007 | 18001 | likely benign | 18 |
1624 | ERBB2 | rs1182661036 | SNP | missense variant | T/I | 218 | 461 | 0.46 | 58 | benign | 0.057 | 14001 | likely benign | 14 |
1625 | ERBB2 | rs1004581055 | SNP | missense variant | V/L | 219 | 541 | 0.54 | 1 | benign | 0 | 3001 | likely benign | 3 |
1626 | ERBB2 | rs772393268 | SNP | missense variant | G/S | 222 | 601 | 0.6 | 2 | benign | 0.001 | 3001 | likely benign | 3 |
1627 | ERBB2 | rs1164981758 | SNP | missense variant | G/D | 222 | 101 | 0.1 | 67 | benign | 0.066 | 16001 | likely benign | 16 |
1628 | ERBB2 | rs1308425150 | SNP | missense variant | G/S | 223 | 171 | 0.17 | 118 | benign | 0.117 | 23001 | likely benign | 23 |
1629 | ERBB2 | rs1390819673 | SNP | missense variant | G/D | 223 | 181 | 0.18 | 646 | possibly damaging | 0.645 | 24001 | likely benign | 24 |
1630 | ERBB2 | rs1404246175 | SNP | missense variant | A/V | 225 | 51 | 0.05 | 118 | benign | 0.117 | 22001 | likely benign | 22 |
1631 | ERBB2 | rs760895559 | SNP | missense variant | R/C | 226 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
1632 | ERBB2 | rs745625627 | SNP | missense variant | R/H | 226 | 1 | 0 | 1000 | probably damaging | 0.999 | 31001 | likely deleterious | 31 |
1633 | ERBB2 | rs981689859 | SNP | missense variant | G/R | 229 | 11 | 0.01 | 998 | probably damaging | 0.997 | 29001 | likely benign | 29 |
1634 | ERBB2 | rs776960538 | SNP | missense variant | P/S | 230 | 151 | 0.15 | 10 | benign | 0.009 | 13001 | likely benign | 13 |
1635 | ERBB2 | rs759753872 | SNP | missense variant | P/T | 232 | 151 | 0.15 | 367 | benign | 0.366 | 14001 | likely benign | 14 |
1636 | ERBB2 | rs1220372519 | SNP | missense variant | C/Y | 235 | 31 | 0.03 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
1637 | ERBB2 | rs1276981083 | SNP | missense variant | H/R | 237 | 1 | 0 | 987 | probably damaging | 0.986 | 26001 | likely benign | 26 |
1638 | ERBB2 | rs752656997 | SNP | missense variant | A/T | 241 | 1 | 0 | 997 | probably damaging | 0.996 | 28001 | likely benign | 28 |
1639 | ERBB2 | rs533090552 | SNP | missense variant | G/S | 243 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
1640 | ERBB2 | rs767309845 | SNP | missense variant | G/V | 243 | 11 | 0.01 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
1641 | ERBB2 | rs1443426897 | SNP | missense variant | C/Y | 244 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
1642 | ERBB2 | rs376183465 | SNP | missense variant | T/M | 245 | 1 | 0 | 999 | probably damaging | 0.998 | 25001 | likely benign | 25 |
1643 | ERBB2 | rs779750598 | SNP | missense variant | S/P | 250 | 1 | 0 | 967 | probably damaging | 0.966 | 27001 | likely benign | 27 |
1644 | ERBB2 | rs777081311 | SNP | missense variant | L/P | 256 | 101 | 0.1 | 836 | possibly damaging | 0.835 | 26001 | likely benign | 26 |
1645 | ERBB2 | rs1567900439 | SNP | missense variant | H/Y | 257 | 11 | 0.01 | 593 | possibly damaging | 0.592 | 24001 | likely benign | 24 |
1646 | ERBB2 | rs769870618 | SNP | missense variant | N/S | 259 | 11 | 0.01 | 670 | possibly damaging | 0.669 | 25001 | likely benign | 25 |
1647 | ERBB2 | rs762919589 | SNP | missense variant | H/Y | 260 | 1 | 0 | 938 | probably damaging | 0.937 | 24001 | likely benign | 24 |
1648 | ERBB2 | rs548076348 | SNP | missense variant | G/D | 262 | 21 | 0.02 | 992 | probably damaging | 0.991 | 27001 | likely benign | 27 |
1649 | ERBB2 | rs750324803 | SNP | missense variant | I/V | 263 | 761 | 0.76 | 1 | benign | 0 | 17001 | likely benign | 17 |
1650 | ERBB2 | rs750324803 | SNP | missense variant | I/F | 263 | 51 | 0.05 | 366 | benign | 0.365 | 23001 | likely benign | 23 |
1651 | ERBB2 | rs773759626 | SNP | missense variant | H/Y | 267 | 41 | 0.04 | 827 | possibly damaging | 0.826 | 25001 | likely benign | 25 |
1652 | ERBB2 | rs200382130 | SNP | missense variant | A/S | 270 | 151 | 0.15 | 8 | benign | 0.007 | 14001 | likely benign | 14 |
1653 | ERBB2 | rs754656388 | SNP | missense variant | A/V | 270 | 31 | 0.03 | 28 | benign | 0.027 | 23001 | likely benign | 23 |
1654 | ERBB2 | rs752295912 | SNP | missense variant | T/I | 273 | 981 | 0.98 | 2 | benign | 0.001 | 12001 | likely benign | 12 |
1655 | ERBB2 | rs757811990 | SNP | missense variant | T/K | 278 | 1 | 0 | 975 | probably damaging | 0.974 | 25001 | likely benign | 25 |
1656 | ERBB2 | rs757811990 | SNP | missense variant | T/M | 278 | 31 | 0.03 | 899 | possibly damaging | 0.898 | 25001 | likely benign | 25 |
1657 | ERBB2 | rs1429013623 | SNP | missense variant | S/Y | 281 | 121 | 0.12 | 970 | probably damaging | 0.969 | 23001 | likely benign | 23 |
1658 | ERBB2 | rs778408285 | SNP | missense variant | M/L | 282 | 361 | 0.36 | 1 | benign | 0 | 15001 | likely benign | 15 |
1659 | ERBB2 | rs1161929692 | SNP | missense variant | M/I | 282 | 231 | 0.23 | 2 | benign | 0.001 | 20001 | likely benign | 20 |
1660 | ERBB2 | rs149210045 | SNP | missense variant | E/K | 286 | 271 | 0.27 | 168 | benign | 0.167 | 22001 | likely benign | 22 |
1661 | ERBB2 | rs149210045 | SNP | missense variant | E/Q | 286 | 251 | 0.25 | 53 | benign | 0.052 | 22001 | likely benign | 22 |
1662 | ERBB2 | rs1387549970 | SNP | missense variant | R/W | 288 | 1 | 0 | 1000 | probably damaging | 0.999 | 31001 | likely deleterious | 31 |
1663 | ERBB2 | rs760205387 | SNP | missense variant | R/Q | 288 | 1 | 0 | 962 | probably damaging | 0.961 | 29001 | likely benign | 29 |
1664 | ERBB2 | rs746190897 | SNP | missense variant | T/A | 290 | 71 | 0.07 | 46 | benign | 0.045 | 23001 | likely benign | 23 |
1665 | ERBB2 | rs775544453 | SNP | missense variant | G/S | 292 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
1666 | ERBB2 | rs1258412021 | SNP | missense variant | A/T | 293 | 1 | 0 | 963 | probably damaging | 0.962 | 27001 | likely benign | 27 |
1667 | ERBB2 | rs866985163 | SNP | missense variant | S/N | 294 | 111 | 0.11 | 512 | possibly damaging | 0.511 | 23001 | likely benign | 23 |
1668 | ERBB2 | rs1191408638 | SNP | missense variant | P/R | 300 | 1 | 0 | 1001 | probably damaging | 1 | 31001 | likely deleterious | 31 |
1669 | ERBB2 | rs1191408638 | SNP | missense variant | P/L | 300 | 1 | 0 | 1001 | probably damaging | 1 | 32001 | likely deleterious | 32 |
1670 | ERBB2 | rs768855063 | SNP | missense variant | N/S | 302 | 1 | 0 | 1001 | probably damaging | 1 | 26001 | likely benign | 26 |
1671 | ERBB2 | rs768855063 | SNP | missense variant | N/I | 302 | 1 | 0 | 1001 | probably damaging | 1 | 25001 | likely benign | 25 |
1672 | ERBB2 | rs1308928763 | SNP | missense variant | T/M | 306 | 171 | 0.17 | 924 | probably damaging | 0.923 | 23001 | likely benign | 23 |
1673 | ERBB2 | rs776515406 | SNP | missense variant | V/M | 308 | 221 | 0.22 | 965 | probably damaging | 0.964 | 23001 | likely benign | 23 |
1674 | ERBB2 | rs1057519787 | SNP | missense variant | G/E | 309 | 1 | 0 | 1001 | probably damaging | 1 | 24001 | likely benign | 24 |
1675 | ERBB2 | rs1057519787 | SNP | missense variant | G/A | 309 | 21 | 0.02 | 998 | probably damaging | 0.997 | 24001 | likely benign | 24 |
1676 | ERBB2 | rs1057519816 | SNP | missense variant | S/Y | 310 | 1 | 0 | 996 | probably damaging | 0.995 | 24001 | likely benign | 24 |
1677 | ERBB2 | rs1057519816 | SNP | missense variant | S/F | 310 | 1 | 0 | 996 | probably damaging | 0.995 | 24001 | likely benign | 24 |
1678 | ERBB2 | rs775294491 | SNP | missense variant | V/I | 314 | 71 | 0.07 | 140 | benign | 0.139 | 18001 | likely benign | 18 |
1679 | ERBB2 | rs762547363 | SNP | missense variant | H/Y | 318 | 11 | 0.01 | 144 | benign | 0.143 | 21001 | likely benign | 21 |
1680 | ERBB2 | rs1396809633 | SNP | missense variant | H/R | 318 | 61 | 0.06 | 2 | benign | 0.001 | 21001 | likely benign | 21 |
1681 | ERBB2 | rs1230152304 | SNP | missense variant | H/Q | 318 | 31 | 0.03 | 51 | benign | 0.05 | 23001 | likely benign | 23 |
1682 | ERBB2 | rs1273270181 | SNP | missense variant | Q/E | 320 | 241 | 0.24 | 324 | benign | 0.323 | 20001 | likely benign | 20 |
1683 | ERBB2 | rs1301941452 | SNP | missense variant | V/A | 322 | 1 | 0 | 982 | probably damaging | 0.981 | 27001 | likely benign | 27 |
1684 | ERBB2 | rs1468532659 | SNP | missense variant | T/S | 323 | 561 | 0.56 | 74 | benign | 0.073 | 18001 | likely benign | 18 |
1685 | ERBB2 | rs1202895125 | SNP | missense variant | E/K | 325 | 91 | 0.09 | 113 | benign | 0.112 | 21001 | likely benign | 21 |
1686 | ERBB2 | rs763793826 | SNP | missense variant | T/K | 328 | 71 | 0.07 | 27 | benign | 0.026 | 20001 | likely benign | 20 |
1687 | ERBB2 | rs763793826 | SNP | missense variant | T/I | 328 | 841 | 0.84 | 19 | benign | 0.018 | 16001 | likely benign | 16 |
1688 | ERBB2 | rs761376658 | SNP | missense variant | R/W | 330 | 1 | 0 | 885 | possibly damaging | 0.884 | 26001 | likely benign | 26 |
1689 | ERBB2 | rs768206712 | SNP | missense variant | R/Q | 330 | 81 | 0.08 | 13 | benign | 0.012 | 23001 | likely benign | 23 |
1690 | ERBB2 | rs564382616 | SNP | missense variant | C/Y | 331 | 1 | 0 | 1001 | probably damaging | 1 | 32001 | likely deleterious | 32 |
1691 | ERBB2 | rs756588194 | SNP | missense variant | E/D | 332 | 161 | 0.16 | 25 | benign | 0.024 | 19001 | likely benign | 19 |
1692 | ERBB2 | rs1409114304 | SNP | missense variant | C/Y | 334 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
1693 | ERBB2 | rs1409114304 | SNP | missense variant | C/F | 334 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
1694 | ERBB2 | rs532077147 | SNP | missense variant | R/Q | 340 | 21 | 0.02 | 4 | benign | 0.003 | 22001 | likely benign | 22 |
1695 | ERBB2 | rs747993530 | SNP | missense variant | Y/C | 343 | 31 | 0.03 | 975 | probably damaging | 0.974 | 29001 | likely benign | 29 |
1696 | ERBB2 | rs758204762 | SNP | missense variant | G/S | 344 | 31 | 0.03 | 984 | probably damaging | 0.983 | 29001 | likely benign | 29 |
1697 | ERBB2 | rs758204762 | SNP | missense variant | G/R | 344 | 1 | 0 | 1000 | probably damaging | 0.999 | 28001 | likely benign | 28 |
1698 | ERBB2 | rs1037129509 | SNP | missense variant | G/D | 344 | 11 | 0.01 | 1000 | probably damaging | 0.999 | 28001 | likely benign | 28 |
1699 | ERBB2 | rs1460443371 | SNP | missense variant | G/S | 346 | 11 | 0.01 | 755 | possibly damaging | 0.754 | 28001 | likely benign | 28 |
1700 | ERBB2 | rs746686273 | SNP | missense variant | M/K | 347 | 81 | 0.08 | 16 | benign | 0.015 | 22001 | likely benign | 22 |
1701 | ERBB2 | rs1263270004 | SNP | missense variant | E/G | 348 | 1001 | 1 | 1 | benign | 0 | 23001 | likely benign | 23 |
1702 | ERBB2 | rs559242250 | SNP | missense variant | L/F | 350 | 191 | 0.19 | 405 | benign | 0.404 | 17001 | likely benign | 17 |
1703 | ERBB2 | rs775972596 | SNP | missense variant | R/Q | 351 | 651 | 0.65 | 6 | benign | 0.005 | 22001 | likely benign | 22 |
1704 | ERBB2 | rs763367024 | SNP | missense variant | E/G | 352 | 971 | 0.97 | 1 | benign | 0 | 21001 | likely benign | 21 |
1705 | ERBB2 | rs769082334 | SNP | missense variant | V/M | 353 | 81 | 0.08 | 351 | benign | 0.35 | 19001 | likely benign | 19 |
1706 | ERBB2 | rs769082334 | SNP | missense variant | V/L | 353 | 121 | 0.12 | 10 | benign | 0.009 | 17001 | likely benign | 17 |
1707 | ERBB2 | rs1197249604 | SNP | missense variant | V/A | 353 | 861 | 0.86 | 4 | benign | 0.003 | 1001 | likely benign | 1 |
1708 | ERBB2 | rs918747921 | SNP | missense variant | R/W | 354 | 21 | 0.02 | 644 | possibly damaging | 0.643 | 25001 | likely benign | 25 |
1709 | ERBB2 | rs1385831939 | SNP | missense variant | T/A | 357 | 1 | 0 | 51 | benign | 0.05 | 23001 | likely benign | 23 |
1710 | ERBB2 | rs373474372 | SNP | missense variant | N/I | 360 | 21 | 0.02 | 897 | possibly damaging | 0.896 | 27001 | likely benign | 27 |
1711 | ERBB2 | rs1324411001 | SNP | missense variant | A/S | 365 | 661 | 0.66 | 6 | benign | 0.005 | 13001 | likely benign | 13 |
1712 | ERBB2 | rs767588058 | SNP | missense variant | G/R | 366 | 11 | 0.01 | 888 | possibly damaging | 0.887 | 28001 | likely benign | 28 |
1713 | ERBB2 | rs1435728387 | SNP | missense variant | G/A | 366 | 11 | 0.01 | 563 | possibly damaging | 0.562 | 25001 | likely benign | 25 |
1714 | ERBB2 | rs1275492389 | SNP | missense variant | I/M | 370 | 1 | 0 | 1000 | probably damaging | 0.999 | 24001 | likely benign | 24 |
1715 | ERBB2 | rs1243660575 | SNP | missense variant | F/C | 371 | 171 | 0.17 | 989 | probably damaging | 0.988 | 25001 | likely benign | 25 |
1716 | ERBB2 | rs149567593 | SNP | missense variant | F/L | 371 | 601 | 0.6 | 565 | possibly damaging | 0.564 | 20001 | likely benign | 20 |
1717 | ERBB2 | rs752664566 | SNP | missense variant | A/T | 375 | 381 | 0.38 | 555 | possibly damaging | 0.554 | 24001 | likely benign | 24 |
1718 | ERBB2 | rs752664566 | SNP | missense variant | A/S | 375 | 521 | 0.52 | 407 | benign | 0.406 | 22001 | likely benign | 22 |
1719 | ERBB2 | rs758210687 | SNP | missense variant | P/L | 378 | 171 | 0.17 | 841 | possibly damaging | 0.84 | 22001 | likely benign | 22 |
1720 | ERBB2 | rs148068883 | SNP | missense variant | S/G | 380 | 501 | 0.5 | 822 | possibly damaging | 0.821 | 24001 | likely benign | 24 |
1721 | ERBB2 | rs1481595696 | SNP | missense variant | D/H | 382 | 271 | 0.27 | 4 | benign | 0.003 | 19001 | likely benign | 19 |
1722 | ERBB2 | rs751270411 | SNP | missense variant | G/E | 383 | 1 | 0 | 999 | probably damaging | 0.998 | 35001 | likely deleterious | 35 |
1723 | ERBB2 | rs753902259 | SNP | missense variant | D/N | 384 | 51 | 0.05 | 237 | benign | 0.236 | 23001 | likely benign | 23 |
1724 | ERBB2 | rs141116145 | SNP | missense variant | A/D | 386 | 141 | 0.14 | 2 | benign | 0.001 | 14001 | likely benign | 14 |
1725 | ERBB2 | rs141116145 | SNP | missense variant | A/G | 386 | 151 | 0.15 | 16 | benign | 0.015 | 14001 | likely benign | 14 |
1726 | ERBB2 | rs780881510 | SNP | missense variant | N/H | 388 | 91 | 0.09 | 54 | benign | 0.053 | 17001 | likely benign | 17 |
1727 | ERBB2 | rs750090147 | SNP | missense variant | N/S | 388 | 141 | 0.14 | 8 | benign | 0.007 | 4001 | likely benign | 4 |
1728 | ERBB2 | rs755701444 | SNP | missense variant | A/T | 390 | 101 | 0.1 | 84 | benign | 0.083 | 11001 | likely benign | 11 |
1729 | ERBB2 | rs587778264 | SNP | missense variant | A/V | 390 | 31 | 0.03 | 19 | benign | 0.018 | 11001 | likely benign | 11 |
1730 | ERBB2 | rs748700504 | SNP | missense variant | P/L | 391 | 11 | 0.01 | 732 | possibly damaging | 0.731 | 22001 | likely benign | 22 |
1731 | ERBB2 | rs772548631 | SNP | missense variant | P/L | 394 | 61 | 0.06 | 218 | benign | 0.217 | 16001 | likely benign | 16 |
1732 | ERBB2 | rs919231881 | SNP | missense variant | E/Q | 395 | 231 | 0.23 | 12 | benign | 0.011 | 15001 | likely benign | 15 |
1733 | ERBB2 | rs773649491 | SNP | missense variant | Q/R | 398 | 391 | 0.39 | 1 | benign | 0 | 1 | likely benign | 0 |
1734 | ERBB2 | rs747239268 | SNP | missense variant | V/M | 399 | 21 | 0.02 | 958 | probably damaging | 0.957 | 23001 | likely benign | 23 |
1735 | ERBB2 | rs377649991 | SNP | missense variant | L/M | 403 | 21 | 0.02 | 991 | probably damaging | 0.99 | 23001 | likely benign | 23 |
1736 | ERBB2 | rs1206146902 | SNP | missense variant | I/T | 406 | 1 | 0 | 997 | probably damaging | 0.996 | 26001 | likely benign | 26 |
1737 | ERBB2 | rs587778265 | SNP | missense variant | Y/D | 411 | 121 | 0.12 | 968 | probably damaging | 0.967 | 25001 | likely benign | 25 |
1738 | ERBB2 | rs758908894 | SNP | missense variant | I/V | 412 | 21 | 0.02 | 967 | probably damaging | 0.966 | 25001 | likely benign | 25 |
1739 | ERBB2 | rs747327229 | SNP | missense variant | P/L | 416 | 1 | 0 | 1000 | probably damaging | 0.999 | 26001 | likely benign | 26 |
1740 | ERBB2 | rs1337551062 | SNP | missense variant | D/H | 417 | 1 | 0 | 619 | possibly damaging | 0.618 | 26001 | likely benign | 26 |
1741 | ERBB2 | rs776714622 | SNP | missense variant | D/A | 417 | 111 | 0.11 | 1 | benign | 0 | 23001 | likely benign | 23 |
1742 | ERBB2 | rs746020984 | SNP | missense variant | L/R | 419 | 311 | 0.31 | 55 | benign | 0.054 | 21001 | likely benign | 21 |
1743 | ERBB2 | rs769778398 | SNP | missense variant | L/I | 422 | 1 | 0 | 994 | probably damaging | 0.993 | 24001 | likely benign | 24 |
1744 | ERBB2 | rs769778398 | SNP | missense variant | L/F | 422 | 111 | 0.11 | 1000 | probably damaging | 0.999 | 23001 | likely benign | 23 |
1745 | ERBB2 | rs199668084 | SNP | missense variant | S/G | 423 | 231 | 0.23 | 70 | benign | 0.069 | 15001 | likely benign | 15 |
1746 | ERBB2 | rs142783371 | SNP | missense variant | V/I | 424 | 101 | 0.1 | 59 | benign | 0.058 | 17001 | likely benign | 17 |
1747 | ERBB2 | rs891454367 | SNP | missense variant | L/V | 428 | 21 | 0.02 | 1001 | probably damaging | 1 | 24001 | likely benign | 24 |
1748 | ERBB2 | rs1322685342 | SNP | missense variant | Q/H | 429 | 161 | 0.16 | 4 | benign | 0.003 | 17001 | likely benign | 17 |
1749 | ERBB2 | rs767398280 | SNP | missense variant | V/I | 430 | 901 | 0.9 | 18 | benign | 0.017 | 15001 | likely benign | 15 |
1750 | ERBB2 | rs367606199 | SNP | missense variant | R/W | 432 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
1751 | ERBB2 | rs1029745309 | SNP | missense variant | R/Q | 432 | 61 | 0.06 | 949 | probably damaging | 0.948 | 26001 | likely benign | 26 |
1752 | ERBB2 | rs1477349434 | SNP | missense variant | G/R | 433 | 21 | 0.02 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
1753 | ERBB2 | rs147382623 | SNP | missense variant | R/Q | 434 | 1 | 0 | 954 | probably damaging | 0.953 | 29001 | likely benign | 29 |
1754 | ERBB2 | rs766083302 | SNP | missense variant | H/Y | 437 | 1001 | 1 | 6 | benign | 0.005 | 14001 | likely benign | 14 |
1755 | ERBB2 | rs756345214 | SNP | missense variant | A/T | 440 | 511 | 0.51 | 28 | benign | 0.027 | 21001 | likely benign | 21 |
1756 | ERBB2 | rs749440298 | SNP | missense variant | S/L | 442 | 481 | 0.48 | 978 | probably damaging | 0.977 | 22001 | likely benign | 22 |
1757 | ERBB2 | rs1351684417 | SNP | missense variant | T/I | 444 | 901 | 0.9 | 212 | benign | 0.211 | 16001 | likely benign | 16 |
1758 | ERBB2 | rs1359828514 | SNP | missense variant | Q/E | 446 | 771 | 0.77 | 8 | benign | 0.007 | 15001 | likely benign | 15 |
1759 | ERBB2 | rs930754368 | SNP | missense variant | G/E | 447 | 361 | 0.36 | 236 | benign | 0.235 | 21001 | likely benign | 21 |
1760 | ERBB2 | rs930754368 | SNP | missense variant | G/A | 447 | 321 | 0.32 | 84 | benign | 0.083 | 20001 | likely benign | 20 |
1761 | ERBB2 | rs1158382665 | SNP | missense variant | G/S | 449 | 531 | 0.53 | 11 | benign | 0.01 | 15001 | likely benign | 15 |
1762 | ERBB2 | rs770857517 | SNP | missense variant | I/V | 450 | 91 | 0.09 | 118 | benign | 0.117 | 19001 | likely benign | 19 |
1763 | ERBB2 | rs1047793418 | SNP | missense variant | S/N | 451 | 311 | 0.31 | 34 | benign | 0.033 | 14001 | likely benign | 14 |
1764 | ERBB2 | rs4252633 | SNP | missense variant | W/C | 452 | 111 | 0.11 | 884 | possibly damaging | 0.883 | 23001 | likely benign | 23 |
1765 | ERBB2 | rs759352819 | SNP | missense variant | L/V | 453 | 1 | 0 | 1001 | probably damaging | 1 | 24001 | likely benign | 24 |
1766 | ERBB2 | rs1410783126 | SNP | missense variant | G/E | 454 | 11 | 0.01 | 1001 | probably damaging | 1 | 26001 | likely benign | 26 |
1767 | ERBB2 | rs200497646 | SNP | missense variant | R/C | 456 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
1768 | ERBB2 | rs1190280142 | SNP | missense variant | E/D | 460 | 11 | 0.01 | 979 | probably damaging | 0.978 | 19001 | likely benign | 19 |
1769 | ERBB2 | rs1457127715 | SNP | missense variant | G/S | 462 | 1001 | 1 | 4 | benign | 0.003 | 14001 | likely benign | 14 |
1770 | ERBB2 | rs1457127715 | SNP | missense variant | G/R | 462 | 1 | 0 | 532 | possibly damaging | 0.531 | 23001 | likely benign | 23 |
1771 | ERBB2 | rs373192991 | SNP | missense variant | G/D | 462 | 21 | 0.02 | 11 | benign | 0.01 | 23001 | likely benign | 23 |
1772 | ERBB2 | rs373192991 | SNP | missense variant | G/V | 462 | 1 | 0 | 449 | possibly damaging | 0.448 | 25001 | likely benign | 25 |
1773 | ERBB2 | rs1399148945 | SNP | missense variant | G/V | 464 | 1 | 0 | 1001 | probably damaging | 1 | 26001 | likely benign | 26 |
1774 | ERBB2 | rs751074421 | SNP | missense variant | A/V | 466 | 1001 | 1 | 1 | benign | 0 | 9001 | likely benign | 9 |
1775 | ERBB2 | rs1328775165 | SNP | missense variant | L/F | 467 | 121 | 0.12 | 629 | possibly damaging | 0.628 | 22001 | likely benign | 22 |
1776 | ERBB2 | rs1374683189 | SNP | missense variant | I/T | 468 | 1 | 0 | 876 | possibly damaging | 0.875 | 24001 | likely benign | 24 |
1777 | ERBB2 | rs201097345 | SNP | missense variant | H/R | 470 | 561 | 0.56 | 1 | benign | 0 | 1001 | likely benign | 1 |
1778 | ERBB2 | rs768049972 | SNP | missense variant | T/I | 472 | 161 | 0.16 | 42 | benign | 0.041 | 6001 | likely benign | 6 |
1779 | ERBB2 | rs756500045 | SNP | missense variant | H/D | 473 | 211 | 0.21 | 4 | benign | 0.003 | 9001 | likely benign | 9 |
1780 | ERBB2 | rs756500045 | SNP | missense variant | H/Y | 473 | 11 | 0.01 | 276 | benign | 0.275 | 14001 | likely benign | 14 |
1781 | ERBB2 | rs1033535912 | SNP | missense variant | L/I | 474 | 1 | 0 | 1001 | probably damaging | 1 | 23001 | likely benign | 23 |
1782 | ERBB2 | rs1033535912 | SNP | missense variant | L/V | 474 | 1 | 0 | 1001 | probably damaging | 1 | 23001 | likely benign | 23 |
1783 | ERBB2 | rs780201941 | SNP | missense variant | F/V | 476 | 11 | 0.01 | 986 | probably damaging | 0.985 | 26001 | likely benign | 26 |
1784 | ERBB2 | rs1025899392 | SNP | missense variant | F/S | 476 | 1 | 0 | 1000 | probably damaging | 0.999 | 27001 | likely benign | 27 |
1785 | ERBB2 | rs755121772 | SNP | missense variant | V/M | 477 | 201 | 0.2 | 235 | benign | 0.234 | 16001 | likely benign | 16 |
1786 | ERBB2 | rs755121772 | SNP | missense variant | V/L | 477 | 671 | 0.67 | 4 | benign | 0.003 | 14001 | likely benign | 14 |
1787 | ERBB2 | rs201021373 | SNP | missense variant | T/M | 479 | 21 | 0.02 | 926 | probably damaging | 0.925 | 24001 | likely benign | 24 |
1788 | ERBB2 | rs370565888 | SNP | missense variant | P/L | 481 | 431 | 0.43 | 945 | probably damaging | 0.944 | 23001 | likely benign | 23 |
1789 | ERBB2 | rs571837012 | SNP | missense variant | D/N | 483 | 471 | 0.47 | 2 | benign | 0.001 | 18001 | likely benign | 18 |
1790 | ERBB2 | rs1160406748 | SNP | missense variant | D/G | 483 | 381 | 0.38 | 6 | benign | 0.005 | 18001 | likely benign | 18 |
1791 | ERBB2 | rs1375073443 | SNP | missense variant | D/E | 483 | 991 | 0.99 | 1 | benign | 0 | 6001 | likely benign | 6 |
1792 | ERBB2 | rs375382055 | SNP | missense variant | R/W | 487 | 41 | 0.04 | 682 | possibly damaging | 0.681 | 25001 | likely benign | 25 |
1793 | ERBB2 | rs371450390 | SNP | missense variant | R/Q | 487 | 211 | 0.21 | 11 | benign | 0.01 | 22001 | likely benign | 22 |
1794 | ERBB2 | rs371450390 | SNP | missense variant | R/P | 487 | 61 | 0.06 | 526 | possibly damaging | 0.525 | 24001 | likely benign | 24 |
1795 | ERBB2 | rs768374532 | SNP | missense variant | N/K | 488 | 91 | 0.09 | 182 | benign | 0.181 | 17001 | likely benign | 17 |
1796 | ERBB2 | rs987507136 | SNP | missense variant | P/S | 489 | 571 | 0.57 | 22 | benign | 0.021 | 17001 | likely benign | 17 |
1797 | ERBB2 | rs142456637 | SNP | missense variant | P/L | 489 | 31 | 0.03 | 541 | possibly damaging | 0.54 | 24001 | likely benign | 24 |
1798 | ERBB2 | rs140670446 | SNP | missense variant | Q/E | 491 | 11 | 0.01 | 970 | probably damaging | 0.969 | 24001 | likely benign | 24 |
1799 | ERBB2 | rs1191789317 | SNP | missense variant | L/V | 493 | 781 | 0.78 | 10 | benign | 0.009 | 15001 | likely benign | 15 |
1800 | ERBB2 | rs879357054 | SNP | missense variant | H/P | 495 | 191 | 0.19 | 104 | benign | 0.103 | 20001 | likely benign | 20 |
1801 | ERBB2 | rs767978749 | SNP | missense variant | T/I | 496 | 251 | 0.25 | 2 | benign | 0.001 | 15001 | likely benign | 15 |
1802 | ERBB2 | rs145762641 | SNP | missense variant | A/T | 497 | 331 | 0.33 | 10 | benign | 0.009 | 21001 | likely benign | 21 |
1803 | ERBB2 | rs1277370521 | SNP | missense variant | N/S | 498 | 1 | 0 | 963 | probably damaging | 0.962 | 25001 | likely benign | 25 |
1804 | ERBB2 | rs199530208 | SNP | missense variant | R/G | 499 | 21 | 0.02 | 233 | benign | 0.232 | 23001 | likely benign | 23 |
1805 | ERBB2 | rs199530208 | SNP | missense variant | R/W | 499 | 1 | 0 | 846 | possibly damaging | 0.845 | 27001 | likely benign | 27 |
1806 | ERBB2 | rs182572604 | SNP | missense variant | R/Q | 499 | 281 | 0.28 | 7 | benign | 0.006 | 21001 | likely benign | 21 |
1807 | ERBB2 | rs182572604 | SNP | missense variant | R/L | 499 | 61 | 0.06 | 11 | benign | 0.01 | 22001 | likely benign | 22 |
1808 | ERBB2 | rs920792523 | SNP | missense variant | P/S | 500 | 521 | 0.52 | 1 | benign | 0 | 19001 | likely benign | 19 |
1809 | ERBB2 | rs1482645941 | SNP | missense variant | E/K | 501 | 351 | 0.35 | 4 | benign | 0.003 | 22001 | likely benign | 22 |
1810 | ERBB2 | rs1482645941 | SNP | missense variant | E/Q | 501 | 341 | 0.34 | 2 | benign | 0.001 | 21001 | likely benign | 21 |
1811 | ERBB2 | rs1198314054 | SNP | missense variant | D/Y | 502 | 11 | 0.01 | 58 | benign | 0.057 | 14001 | likely benign | 14 |
1812 | ERBB2 | rs752759368 | SNP | missense variant | D/E | 502 | 1001 | 1 | 1 | benign | 0 | 1 | likely benign | 0 |
1813 | ERBB2 | rs758497995 | SNP | missense variant | E/K | 503 | 551 | 0.55 | 20 | benign | 0.019 | 22001 | likely benign | 22 |
1814 | ERBB2 | rs983576212 | SNP | missense variant | E/D | 503 | 441 | 0.44 | 1 | benign | 0 | 15001 | likely benign | 15 |
1815 | ERBB2 | rs1358325733 | SNP | missense variant | G/S | 506 | 501 | 0.5 | 1 | benign | 0 | 10001 | likely benign | 10 |
1816 | ERBB2 | rs1293998208 | SNP | missense variant | E/K | 507 | 201 | 0.2 | 1 | benign | 0 | 9001 | likely benign | 9 |
1817 | ERBB2 | rs1377085949 | SNP | missense variant | H/Y | 512 | 581 | 0.58 | 1 | benign | 0 | 1 | likely benign | 0 |
1818 | ERBB2 | rs1238891256 | SNP | missense variant | Q/H | 513 | 311 | 0.31 | 1 | benign | 0 | 1 | likely benign | 0 |
1819 | ERBB2 | rs371623072 | SNP | missense variant | A/T | 516 | 261 | 0.26 | 10 | benign | 0.009 | 17001 | likely benign | 17 |
1820 | ERBB2 | rs759579850 | SNP | missense variant | R/Q | 517 | 481 | 0.48 | 1 | benign | 0 | 14001 | likely benign | 14 |
1821 | ERBB2 | rs759579850 | SNP | missense variant | R/P | 517 | 261 | 0.26 | 1 | benign | 0 | 16001 | likely benign | 16 |
1822 | ERBB2 | rs561322621 | SNP | missense variant | G/D | 522 | 1 | 0 | 1001 | probably damaging | 1 | 28001 | likely benign | 28 |
1823 | ERBB2 | rs561322621 | SNP | missense variant | G/V | 522 | 11 | 0.01 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
1824 | ERBB2 | rs202202058 | SNP | missense variant | P/S | 523 | 51 | 0.05 | 801 | possibly damaging | 0.8 | 25001 | likely benign | 25 |
1825 | ERBB2 | rs1176949914 | SNP | missense variant | G/E | 524 | 91 | 0.09 | 893 | possibly damaging | 0.892 | 24001 | likely benign | 24 |
1826 | ERBB2 | rs1317541157 | SNP | missense variant | Q/H | 527 | 91 | 0.09 | 83 | benign | 0.082 | 22001 | likely benign | 22 |
1827 | ERBB2 | rs747838206 | SNP | missense variant | V/I | 529 | 71 | 0.07 | 7 | benign | 0.006 | 20001 | likely benign | 20 |
1828 | ERBB2 | rs771580372 | SNP | missense variant | N/S | 530 | 1001 | 1 | 1 | benign | 0 | 15001 | likely benign | 15 |
1829 | ERBB2 | rs140711914 | SNP | missense variant | C/R | 531 | 1 | 0 | 1001 | probably damaging | 1 | 29001 | likely benign | 29 |
1830 | ERBB2 | rs777363214 | SNP | missense variant | S/R | 532 | 1001 | 1 | 2 | benign | 0.001 | 13001 | likely benign | 13 |
1831 | ERBB2 | rs746476368 | SNP | missense variant | L/F | 535 | 711 | 0.71 | 584 | possibly damaging | 0.583 | 23001 | likely benign | 23 |
1832 | ERBB2 | rs140980495 | SNP | missense variant | R/Q | 536 | 1 | 0 | 998 | probably damaging | 0.997 | 32001 | likely deleterious | 32 |
1833 | ERBB2 | rs866163885 | SNP | missense variant | G/S | 537 | 41 | 0.04 | 303 | benign | 0.302 | 24001 | likely benign | 24 |
1834 | ERBB2 | rs866163885 | SNP | missense variant | G/R | 537 | 81 | 0.08 | 414 | benign | 0.413 | 23001 | likely benign | 23 |
1835 | ERBB2 | rs777116958 | SNP | missense variant | Q/H | 538 | 151 | 0.15 | 2 | benign | 0.001 | 16001 | likely benign | 16 |
1836 | ERBB2 | rs1415101808 | SNP | missense variant | V/M | 541 | 11 | 0.01 | 905 | possibly damaging | 0.904 | 27001 | likely benign | 27 |
1837 | ERBB2 | rs150203173 | SNP | missense variant | R/Q | 545 | 1 | 0 | 40 | benign | 0.039 | 24001 | likely benign | 24 |
1838 | ERBB2 | rs565582943 | SNP | missense variant | Q/K | 548 | 221 | 0.22 | 1 | benign | 0 | 19001 | likely benign | 19 |
1839 | ERBB2 | rs532713027 | SNP | missense variant | G/W | 549 | 1 | 0 | 1000 | probably damaging | 0.999 | 14001 | likely benign | 14 |
1840 | ERBB2 | rs1224275634 | SNP | missense variant | L/V | 550 | 271 | 0.27 | 2 | benign | 0.001 | 11001 | likely benign | 11 |
1841 | ERBB2 | rs1430713880 | SNP | missense variant | A/V | 557 | 1 | 0 | 8 | benign | 0.007 | 16001 | likely benign | 16 |
1842 | ERBB2 | rs767713671 | SNP | missense variant | H/Q | 559 | 341 | 0.34 | 1 | benign | 0 | 12001 | likely benign | 12 |
1843 | ERBB2 | rs201470725 | SNP | missense variant | P/L | 562 | 151 | 0.15 | 4 | benign | 0.003 | 16001 | likely benign | 16 |
1844 | ERBB2 | rs1299172694 | SNP | missense variant | P/R | 565 | 1 | 0 | 373 | benign | 0.372 | 22001 | likely benign | 22 |
1845 | ERBB2 | rs1398622638 | SNP | missense variant | C/R | 567 | 1 | 0 | 1000 | probably damaging | 0.999 | 27001 | likely benign | 27 |
1846 | ERBB2 | rs1285769371 | SNP | missense variant | Q/E | 568 | 251 | 0.25 | 6 | benign | 0.005 | 17001 | likely benign | 17 |
1847 | ERBB2 | rs763863372 | SNP | missense variant | P/L | 569 | 141 | 0.14 | 63 | benign | 0.062 | 22001 | likely benign | 22 |
1848 | ERBB2 | rs1218756471 | SNP | missense variant | Q/E | 570 | 481 | 0.48 | 821 | possibly damaging | 0.82 | 22001 | likely benign | 22 |
1849 | ERBB2 | rs756836001 | SNP | missense variant | G/V | 572 | 21 | 0.02 | 277 | benign | 0.276 | 22001 | likely benign | 22 |
1850 | ERBB2 | rs1195763693 | SNP | missense variant | V/M | 574 | 121 | 0.12 | 74 | benign | 0.073 | 19001 | likely benign | 19 |
1851 | ERBB2 | rs778479390 | SNP | missense variant | F/C | 577 | 181 | 0.18 | 269 | benign | 0.268 | 13001 | likely benign | 13 |
1852 | ERBB2 | rs1252848592 | SNP | missense variant | G/E | 578 | 1 | 0 | 999 | probably damaging | 0.998 | 25001 | likely benign | 25 |
1853 | ERBB2 | rs756686824 | SNP | missense variant | P/L | 579 | 41 | 0.04 | 8 | benign | 0.007 | 23001 | likely benign | 23 |
1854 | ERBB2 | rs1287673125 | SNP | missense variant | V/E | 585 | 161 | 0.16 | 1 | benign | 0 | 19001 | likely benign | 19 |
1855 | ERBB2 | rs1237088846 | SNP | missense variant | H/Y | 589 | 1 | 0 | 967 | probably damaging | 0.966 | 24001 | likely benign | 24 |
1856 | ERBB2 | rs767216520 | SNP | missense variant | K/M | 591 | 61 | 0.06 | 67 | benign | 0.066 | 22001 | likely benign | 22 |
1857 | ERBB2 | rs931758036 | SNP | missense variant | D/E | 592 | 1 | 0 | 1000 | probably damaging | 0.999 | 19001 | likely benign | 19 |
1858 | ERBB2 | rs750092447 | SNP | missense variant | P/L | 593 | 1 | 0 | 29 | benign | 0.028 | 18001 | likely benign | 18 |
1859 | ERBB2 | rs760310908 | SNP | missense variant | P/H | 594 | 11 | 0.01 | 560 | possibly damaging | 0.559 | 22001 | likely benign | 22 |
1860 | ERBB2 | rs755483857 | SNP | missense variant | V/M | 597 | 1 | 0 | 997 | probably damaging | 0.996 | 27001 | likely benign | 27 |
1861 | ERBB2 | rs145409713 | SNP | missense variant | A/D | 598 | 231 | 0.23 | 6 | benign | 0.005 | 19001 | likely benign | 19 |
1862 | ERBB2 | rs145409713 | SNP | missense variant | A/G | 598 | 91 | 0.09 | 47 | benign | 0.046 | 19001 | likely benign | 19 |
1863 | ERBB2 | rs369903296 | SNP | missense variant | R/C | 599 | 1 | 0 | 891 | possibly damaging | 0.89 | 25001 | likely benign | 25 |
1864 | ERBB2 | rs758820578 | SNP | missense variant | R/H | 599 | 261 | 0.26 | 11 | benign | 0.01 | 18001 | likely benign | 18 |
1865 | ERBB2 | rs747200104 | SNP | missense variant | S/R | 602 | 121 | 0.12 | 677 | possibly damaging | 0.676 | 14001 | likely benign | 14 |
1866 | ERBB2 | rs771145294 | SNP | missense variant | G/S | 603 | 11 | 0.01 | 999 | probably damaging | 0.998 | 28001 | likely benign | 28 |
1867 | ERBB2 | rs781179380 | SNP | missense variant | G/D | 603 | 1 | 0 | 999 | probably damaging | 0.998 | 27001 | likely benign | 27 |
1868 | ERBB2 | rs1282253805 | SNP | missense variant | K/T | 605 | 151 | 0.15 | 598 | possibly damaging | 0.597 | 24001 | likely benign | 24 |
1869 | ERBB2 | rs1282253805 | SNP | missense variant | K/R | 605 | 451 | 0.45 | 328 | benign | 0.327 | 22001 | likely benign | 22 |
1870 | ERBB2 | rs1219238007 | SNP | missense variant | D/N | 607 | 131 | 0.13 | 36 | benign | 0.035 | 23001 | likely benign | 23 |
1871 | ERBB2 | rs1256869007 | SNP | missense variant | D/G | 607 | 241 | 0.24 | 386 | benign | 0.385 | 23001 | likely benign | 23 |
1872 | ERBB2 | rs1304926892 | SNP | missense variant | S/F | 609 | 1 | 0 | 37 | benign | 0.036 | 23001 | likely benign | 23 |
1873 | ERBB2 | rs774261411 | SNP | missense variant | Y/H | 610 | 561 | 0.56 | 128 | benign | 0.127 | 22001 | likely benign | 22 |
1874 | ERBB2 | rs377370642 | SNP | missense variant | M/V | 611 | 441 | 0.44 | 1 | benign | 0 | 19001 | likely benign | 19 |
1875 | ERBB2 | rs1312573525 | SNP | missense variant | K/R | 615 | 1 | 0 | 991 | probably damaging | 0.99 | 28001 | likely benign | 28 |
1876 | ERBB2 | rs1413869243 | SNP | missense variant | F/L | 616 | 1 | 0 | 29 | benign | 0.028 | 21001 | likely benign | 21 |
1877 | ERBB2 | rs766029214 | SNP | missense variant | A/T | 622 | 471 | 0.47 | 1 | benign | 0 | 12001 | likely benign | 12 |
1878 | ERBB2 | rs759078493 | SNP | missense variant | P/L | 625 | 311 | 0.31 | 2 | benign | 0.001 | 14001 | likely benign | 14 |
1879 | ERBB2 | rs1173337736 | SNP | missense variant | P/S | 627 | 111 | 0.11 | 109 | benign | 0.108 | 22001 | likely benign | 22 |
1880 | ERBB2 | rs1412157429 | SNP | missense variant | I/L | 628 | 321 | 0.32 | 8 | benign | 0.007 | 22001 | likely benign | 22 |
1881 | ERBB2 | rs753267835 | SNP | missense variant | N/D | 629 | 1 | 0 | 923 | probably damaging | 0.922 | 27001 | likely benign | 27 |
1882 | ERBB2 | rs758907167 | SNP | missense variant | N/T | 629 | 21 | 0.02 | 666 | possibly damaging | 0.665 | 26001 | likely benign | 26 |
1883 | ERBB2 | rs1258745095 | SNP | missense variant | T/S | 631 | 101 | 0.1 | 186 | benign | 0.185 | 21001 | likely benign | 21 |
1884 | ERBB2 | rs778312796 | SNP | missense variant | H/Y | 632 | 1001 | 1 | 12 | benign | 0.011 | 18001 | likely benign | 18 |
1885 | ERBB2 | rs199726056 | SNP | missense variant | S/F | 633 | 1 | 0 | 556 | possibly damaging | 0.555 | 25001 | likely benign | 25 |
1886 | ERBB2 | rs367599823 | SNP | missense variant | P/R | 643 | 61 | 0.06 | 249 | benign | 0.248 | 23001 | likely benign | 23 |
1887 | ERBB2 | rs750665964 | SNP | missense variant | A/T | 644 | 431 | 0.43 | 12 | benign | 0.011 | 22001 | likely benign | 22 |
1888 | ERBB2 | rs370514427 | SNP | missense variant | E/K | 645 | 761 | 0.76 | 12 | benign | 0.011 | 23001 | likely benign | 23 |
1889 | ERBB2 | rs201784472 | SNP | missense variant | R/K | 647 | 851 | 0.85 | 1 | benign | 0 | 22001 | likely benign | 22 |
1890 | ERBB2 | rs201784472 | SNP | missense variant | R/T | 647 | 391 | 0.39 | 46 | benign | 0.045 | 22001 | likely benign | 22 |
1891 | ERBB2 | rs777759226 | SNP | missense variant | A/T | 648 | 741 | 0.74 | 13 | benign | 0.012 | 20001 | likely benign | 20 |
1892 | ERBB2 | rs1332779143 | SNP | missense variant | P/S | 650 | 181 | 0.18 | 4 | benign | 0.003 | 22001 | likely benign | 22 |
1893 | ERBB2 | rs778798172 | SNP | missense variant | P/L | 650 | 111 | 0.11 | 1 | benign | 0 | 22001 | likely benign | 22 |
1894 | ERBB2 | rs1801201 | SNP | missense variant | I/L | 654 | 221 | 0.22 | 86 | benign | 0.085 | 22001 | likely benign | 22 |
1895 | ERBB2 | rs1801201 | SNP | missense variant | I/V | 654 | 171 | 0.17 | 86 | benign | 0.085 | 22001 | likely benign | 22 |
1896 | ERBB2 | rs1136201 | SNP | missense variant | I/V | 655 | 751 | 0.75 | 109 | benign | 0.108 | 19001 | likely benign | 19 |
1897 | ERBB2 | rs1136201 | SNP | missense variant | I/F | 655 | 41 | 0.04 | 734 | possibly damaging | 0.733 | 26001 | likely benign | 26 |
1898 | ERBB2 | rs1317387900 | SNP | missense variant | G/S | 660 | 61 | 0.06 | 865 | possibly damaging | 0.864 | 27001 | likely benign | 27 |
1899 | ERBB2 | rs1196929947 | SNP | missense variant | G/D | 660 | 1 | 0 | 992 | probably damaging | 0.991 | 27001 | likely benign | 27 |
1900 | ERBB2 | rs762407538 | SNP | missense variant | I/V | 661 | 941 | 0.94 | 1 | benign | 0 | 1 | likely benign | 0 |
1901 | ERBB2 | rs1483724551 | SNP | missense variant | L/V | 662 | 181 | 0.18 | 409 | benign | 0.408 | 18001 | likely benign | 18 |
1902 | ERBB2 | rs1567911318 | SNP | missense variant | V/M | 665 | 61 | 0.06 | 43 | benign | 0.042 | 2001 | likely benign | 2 |
1903 | ERBB2 | rs372616729 | SNP | missense variant | G/R | 668 | 101 | 0.1 | 106 | benign | 0.105 | 15001 | likely benign | 15 |
1904 | ERBB2 | rs372616729 | SNP | missense variant | G/R | 668 | 101 | 0.1 | 106 | benign | 0.105 | 15001 | likely benign | 15 |
1905 | ERBB2 | rs900792840 | SNP | missense variant | V/M | 669 | 31 | 0.03 | 58 | benign | 0.057 | 6001 | likely benign | 6 |
1906 | ERBB2 | rs1312937127 | SNP | missense variant | V/G | 670 | 481 | 0.48 | 105 | benign | 0.104 | 15001 | likely benign | 15 |
1907 | ERBB2 | rs1168496712 | SNP | missense variant | F/L | 671 | 1001 | 1 | 1 | benign | 0 | 1 | likely benign | 0 |
1908 | ERBB2 | rs1423654581 | SNP | missense variant | I/N | 673 | 1 | 0 | 43 | benign | 0.042 | 20001 | likely benign | 20 |
1909 | ERBB2 | rs996814735 | SNP | missense variant | I/V | 675 | 771 | 0.77 | 7 | benign | 0.006 | 4001 | likely benign | 4 |
1910 | ERBB2 | rs1418604945 | SNP | missense variant | K/M | 676 | 131 | 0.13 | 8 | benign | 0.007 | 22001 | likely benign | 22 |
1911 | ERBB2 | rs1167835335 | SNP | missense variant | R/Q | 677 | 1 | 0 | 1000 | probably damaging | 0.999 | 29001 | likely benign | 29 |
1912 | ERBB2 | rs1377979176 | SNP | missense variant | R/W | 678 | 1 | 0 | 119 | benign | 0.118 | 17001 | likely benign | 17 |
1913 | ERBB2 | rs1057519862 | SNP | missense variant | R/Q | 678 | 191 | 0.19 | 104 | benign | 0.103 | 23001 | likely benign | 23 |
1914 | ERBB2 | rs759608479 | SNP | missense variant | Q/E | 679 | 21 | 0.02 | 1 | benign | 0 | 19001 | likely benign | 19 |
1915 | ERBB2 | rs765387989 | SNP | missense variant | R/Q | 683 | 1 | 0 | 939 | probably damaging | 0.938 | 31001 | likely deleterious | 31 |
1916 | ERBB2 | rs765387989 | SNP | missense variant | R/P | 683 | 1 | 0 | 986 | probably damaging | 0.985 | 32001 | likely deleterious | 32 |
1917 | ERBB2 | rs1302627802 | SNP | missense variant | K/R | 684 | 81 | 0.08 | 832 | possibly damaging | 0.831 | 26001 | likely benign | 26 |
1918 | ERBB2 | rs752669313 | SNP | missense variant | Y/H | 685 | 161 | 0.16 | 1 | benign | 0 | 23001 | likely benign | 23 |
1919 | ERBB2 | rs1190122730 | SNP | missense variant | T/M | 686 | 1 | 0 | 997 | probably damaging | 0.996 | 26001 | likely benign | 26 |
1920 | ERBB2 | rs1402335179 | SNP | missense variant | M/L | 687 | 1001 | 1 | 20 | benign | 0.019 | 19001 | likely benign | 19 |
1921 | ERBB2 | rs867851148 | SNP | missense variant | Q/K | 692 | 61 | 0.06 | 984 | probably damaging | 0.983 | 24001 | likely benign | 24 |
1922 | ERBB2 | rs1192572638 | SNP | missense variant | P/T | 699 | 1 | 0 | 1001 | probably damaging | 1 | 26001 | likely benign | 26 |
1923 | ERBB2 | rs1441217225 | SNP | missense variant | T/I | 701 | 1 | 0 | 993 | probably damaging | 0.992 | 27001 | likely benign | 27 |
1924 | ERBB2 | rs34602395 | SNP | missense variant | S/I | 703 | 1 | 0 | 1001 | probably damaging | 1 | 27001 | likely benign | 27 |
1925 | ERBB2 | rs868026167 | SNP | missense variant | G/R | 704 | 1 | 0 | 1001 | probably damaging | 1 | 31001 | likely deleterious | 31 |
1926 | ERBB2 | rs1265427684 | SNP | missense variant | N/K | 708 | 1 | 0 | 990 | probably damaging | 0.989 | 24001 | likely benign | 24 |
1927 | ERBB2 | rs959346230 | SNP | missense variant | Q/K | 709 | 31 | 0.03 | 998 | probably damaging | 0.997 | 25001 | likely benign | 25 |
1928 | ERBB2 | rs991114244 | SNP | missense variant | M/L | 712 | 1001 | 1 | 8 | benign | 0.007 | 19001 | likely benign | 19 |
1929 | ERBB2 | rs756073738 | SNP | missense variant | M/R | 712 | 1 | 0 | 886 | possibly damaging | 0.885 | 28001 | likely benign | 28 |
1930 | ERBB2 | rs779034594 | SNP | missense variant | R/Q | 713 | 1 | 0 | 999 | probably damaging | 0.998 | 32001 | likely deleterious | 32 |
1931 | ERBB2 | rs967815855 | SNP | missense variant | E/K | 719 | 1 | 0 | 953 | probably damaging | 0.952 | 29001 | likely benign | 29 |
1932 | ERBB2 | rs977818812 | SNP | missense variant | E/V | 719 | 1 | 0 | 991 | probably damaging | 0.99 | 31001 | likely deleterious | 31 |
1933 | ERBB2 | rs1221984925 | SNP | missense variant | V/M | 723 | 41 | 0.04 | 63 | benign | 0.062 | 23001 | likely benign | 23 |
1934 | ERBB2 | rs1452141491 | SNP | missense variant | A/T | 730 | 1 | 0 | 1001 | probably damaging | 1 | 31001 | likely deleterious | 31 |
19 |